BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 12473184)

  • 1. Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death.
    Altman A; Villalba M
    J Biochem; 2002 Dec; 132(6):841-6. PubMed ID: 12473184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C(theta) in T cell activation.
    Isakov N; Altman A
    Annu Rev Immunol; 2002; 20():761-94. PubMed ID: 11861617
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells.
    Hehner SP; Li-Weber M; Giaisi M; Dröge W; Krammer PH; Schmitz ML
    J Immunol; 2000 Apr; 164(7):3829-36. PubMed ID: 10725744
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.
    Villalba M; Bi K; Hu J; Altman Y; Bushway P; Reits E; Neefjes J; Baier G; Abraham RT; Altman A
    J Cell Biol; 2002 Apr; 157(2):253-63. PubMed ID: 11956228
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.
    Lin X; O'Mahony A; Mu Y; Geleziunas R; Greene WC
    Mol Cell Biol; 2000 Apr; 20(8):2933-40. PubMed ID: 10733597
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.
    Herndon TM; Shan XC; Tsokos GC; Wange RL
    J Immunol; 2001 May; 166(9):5654-64. PubMed ID: 11313406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase C-theta (PKCtheta): it's all about location, location, location.
    Altman A; Villalba M
    Immunol Rev; 2003 Apr; 192():53-63. PubMed ID: 12670395
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aplotaxene blocks T cell activation by modulation of protein kinase C-θ-dependent pathway.
    Na BR; Kim HR; Kwon MS; Lee HS; Piragyte I; Choi EJ; Choi HK; Han WC; Lee SH; Jun CD
    Food Chem Toxicol; 2013 Dec; 62():23-31. PubMed ID: 23941771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.
    Dienz O; Möller A; Strecker A; Stephan N; Krammer PH; Dröge W; Schmitz ML
    J Immunol; 2003 Jan; 170(1):365-72. PubMed ID: 12496421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.
    Qiao G; Li Z; Molinero L; Alegre ML; Ying H; Sun Z; Penninger JM; Zhang J
    Mol Cell Biol; 2008 Apr; 28(7):2470-80. PubMed ID: 18227156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein kinase Ctheta: a new essential superstar on the T-cell stage.
    Altman A; Isakov N; Baier G
    Immunol Today; 2000 Nov; 21(11):567-73. PubMed ID: 11094261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28.
    Kong KF; Yokosuka T; Canonigo-Balancio AJ; Isakov N; Saito T; Altman A
    Nat Immunol; 2011 Oct; 12(11):1105-12. PubMed ID: 21964608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes.
    Sun Z; Arendt CW; Ellmeier W; Schaeffer EM; Sunshine MJ; Gandhi L; Annes J; Petrzilka D; Kupfer A; Schwartzberg PL; Littman DR
    Nature; 2000 Mar; 404(6776):402-7. PubMed ID: 10746729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein kinase C-theta inhibitors: a novel therapy for inflammatory disorders.
    Chand S; Mehta N; Bahia MS; Dixit A; Silakari O
    Curr Pharm Des; 2012; 18(30):4725-46. PubMed ID: 22830352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Signals and sequences that control CD28 localization to the central region of the immunological synapse.
    Sanchez-Lockhart M; Graf B; Miller J
    J Immunol; 2008 Dec; 181(11):7639-48. PubMed ID: 19017952
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation.
    Bi K; Tanaka Y; Coudronniere N; Sugie K; Hong S; van Stipdonk MJ; Altman A
    Nat Immunol; 2001 Jun; 2(6):556-63. PubMed ID: 11376344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.
    Khoshnan A; Bae D; Tindell CA; Nel AE
    J Immunol; 2000 Dec; 165(12):6933-40. PubMed ID: 11120819
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.
    Villalba M; Coudronniere N; Deckert M; Teixeiro E; Mas P; Altman A
    Immunity; 2000 Feb; 12(2):151-60. PubMed ID: 10714681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation.
    Wang XD; Gong Y; Chen ZL; Gong BN; Xie JJ; Zhong CQ; Wang QL; Diao LH; Xu A; Han J; Altman A; Li Y
    Nat Immunol; 2015 Nov; 16(11):1195-203. PubMed ID: 26390157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Filamin A is required for T cell activation mediated by protein kinase C-theta.
    Hayashi K; Altman A
    J Immunol; 2006 Aug; 177(3):1721-8. PubMed ID: 16849481
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.