BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 12477049)

  • 41. DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
    Saiki Y; Yoshino Y; Fujimura H; Manabe T; Kudo Y; Shimada M; Mano N; Nakano T; Lee Y; Shimizu S; Oba S; Fujiwara S; Shimizu H; Chen N; Nezhad ZK; Jin G; Fukushige S; Sunamura M; Ishida M; Motoi F; Egawa S; Unno M; Horii A
    Biochem Biophys Res Commun; 2012 Apr; 421(1):98-104. PubMed ID: 22490663
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Quantitative Targeted Proteomics of Pancreatic Cancer: Deoxycytidine Kinase Protein Level Correlates to Progression-Free Survival of Patients Receiving Gemcitabine Treatment.
    Ohmine K; Kawaguchi K; Ohtsuki S; Motoi F; Ohtsuka H; Kamiie J; Abe T; Unno M; Terasaki T
    Mol Pharm; 2015 Sep; 12(9):3282-91. PubMed ID: 26280109
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer.
    Ohhashi S; Ohuchida K; Mizumoto K; Fujita H; Egami T; Yu J; Toma H; Sadatomi S; Nagai E; Tanaka M
    Anticancer Res; 2008; 28(4B):2205-12. PubMed ID: 18751396
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Gene therapy based on gemcitabine chemosensitization suppresses pancreatic tumor growth.
    Vernejoul F; Ghénassia L; Souque A; Lulka H; Drocourt D; Cordelier P; Pradayrol L; Pyronnet S; Buscail L; Tiraby G
    Mol Ther; 2006 Dec; 14(6):758-67. PubMed ID: 17000136
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer.
    Sigmond J; Honeywell RJ; Postma TJ; Dirven CM; de Lange SM; van der Born K; Laan AC; Baayen JC; Van Groeningen CJ; Bergman AM; Giaccone G; Peters GJ
    Ann Oncol; 2009 Jan; 20(1):182-7. PubMed ID: 18701427
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants.
    Lamba JK; Crews K; Pounds S; Schuetz EG; Gresham J; Gandhi V; Plunkett W; Rubnitz J; Ribeiro R
    J Pharmacol Exp Ther; 2007 Dec; 323(3):935-45. PubMed ID: 17855478
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.
    Giovannetti E; Del Tacca M; Mey V; Funel N; Nannizzi S; Ricci S; Orlandini C; Boggi U; Campani D; Del Chiaro M; Iannopollo M; Bevilacqua G; Mosca F; Danesi R
    Cancer Res; 2006 Apr; 66(7):3928-35. PubMed ID: 16585222
    [TBL] [Abstract][Full Text] [Related]  

  • 48. pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs.
    Williams TK; Costantino CL; Bildzukewicz NA; Richards NG; Rittenhouse DW; Einstein L; Cozzitorto JA; Keen JC; Dasgupta A; Gorospe M; Gonye GE; Yeo CJ; Witkiewicz AK; Brody JR
    PLoS One; 2010 Nov; 5(11):e15455. PubMed ID: 21152064
    [TBL] [Abstract][Full Text] [Related]  

  • 49. The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.
    Costantino CL; Witkiewicz AK; Kuwano Y; Cozzitorto JA; Kennedy EP; Dasgupta A; Keen JC; Yeo CJ; Gorospe M; Brody JR
    Cancer Res; 2009 Jun; 69(11):4567-72. PubMed ID: 19487279
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase.
    Sigmond J; Bergman AM; Leon LG; Loves WJ; Hoebe EK; Peters GJ
    Anticancer Drugs; 2010 Jul; 21(6):591-9. PubMed ID: 20436341
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Study of apoptosis induction and deoxycytidine kinase/cytidine deaminase modulation in the synergistic interaction of a novel ceramide analog and gemcitabine in pancreatic cancer cells.
    Giovannetti E; Leon LG; Bertini S; Macchia M; Minutolo F; Funel N; Alecci C; Giancola F; Danesi R; Peters GJ
    Nucleosides Nucleotides Nucleic Acids; 2010 Jun; 29(4-6):419-26. PubMed ID: 20544530
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.
    Kocabas NA; Aksoy P; Pelleymounter LL; Moon I; Ryu JS; Gilbert JA; Salavaggione OE; Eckloff BW; Wieben ED; Yee V; Weinshilboum RM; Ames MM
    Drug Metab Dispos; 2008 Sep; 36(9):1951-9. PubMed ID: 18556440
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Ribonucleotide reductase subunit M1 assessed by quantitative double-fluorescence immunohistochemistry predicts the efficacy of gemcitabine in biliary tract carcinoma.
    Nakamura J; Kohya N; Kai K; Ohtaka K; Hashiguchi K; Hiraki M; Kitajima Y; Tokunaga O; Noshiro H; Miyazaki K
    Int J Oncol; 2010 Oct; 37(4):845-52. PubMed ID: 20811706
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Roles for hENT1 and dCK in gemcitabine sensitivity and malignancy of meningioma.
    Yamamoto M; Sanomachi T; Suzuki S; Uchida H; Yonezawa H; Higa N; Takajo T; Yamada Y; Sugai A; Togashi K; Seino S; Okada M; Sonoda Y; Hirano H; Yoshimoto K; Kitanaka C
    Neuro Oncol; 2021 Jun; 23(6):945-954. PubMed ID: 33556172
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity.
    Ge Y; Jensen TL; Matherly LH; Taub JW
    J Biol Chem; 2003 Dec; 278(50):49901-10. PubMed ID: 14514691
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK.
    Nakano T; Saiki Y; Kudo C; Hirayama A; Mizuguchi Y; Fujiwara S; Soga T; Sunamura M; Matsumura N; Motoi F; Unno M; Horii A
    Biochem Biophys Res Commun; 2015 Sep; 464(4):1084-1089. PubMed ID: 26196746
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Evaluation of a UCMK/dCK fusion enzyme for gemcitabine-mediated cytotoxicity.
    Johnson AJ; Brown MN; Black ME
    Biochem Biophys Res Commun; 2011 Dec; 416(1-2):199-204. PubMed ID: 22093835
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines.
    Giovannetti E; Mey V; Danesi R; Mosca I; Del Tacca M
    Clin Cancer Res; 2004 May; 10(9):2936-43. PubMed ID: 15131028
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Optimizing pemetrexed-gemcitabine combination in patients with advanced non-small cell lung cancer: a pharmacogenetic approach.
    De Pas TM; Toffalorio F; Giovannetti E; Radice D; Russo F; Angeli I; Calamai G; Spitaleri G; Catania C; Noberasco C; Milani A; Pelosi G; Danesi R; De Braud F
    J Thorac Oncol; 2011 Apr; 6(4):768-73. PubMed ID: 21336182
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Relationship between single nucleotide polymorphisms in the deoxycytidine kinase gene and chemosensitivity of gemcitabine in six pancreatic cancer cell lines.
    Si S; Liao Q; Zhao YP; Hu Y; Zhang Q; You LL
    Chin Med J (Engl); 2011 Feb; 124(3):419-22. PubMed ID: 21362344
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.