130 related articles for article (PubMed ID: 12477052)
1. CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
Yoon JT; Palazzo AF; Xiao D; Delohery TM; Warburton PE; Bruce JN; Thompson WJ; Sperl G; Whitehead C; Fetter J; Pamukcu R; Gundersen GG; Weinstein IB
Mol Cancer Ther; 2002 Apr; 1(6):393-404. PubMed ID: 12477052
[TBL] [Abstract][Full Text] [Related]
2. The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization.
Xiao D; Deguchi A; Gundersen GG; Oehlen B; Arnold L; Weinstein IB
Mol Cancer Ther; 2006 Jan; 5(1):60-7. PubMed ID: 16432163
[TBL] [Abstract][Full Text] [Related]
3. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
Piazza GA; Thompson WJ; Pamukcu R; Alila HW; Whitehead CM; Liu L; Fetter JR; Gresh WE; Klein-Szanto AJ; Farnell DR; Eto I; Grubbs CJ
Cancer Res; 2001 May; 61(10):3961-8. PubMed ID: 11358813
[TBL] [Abstract][Full Text] [Related]
4. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
Liu L; Li H; Underwood T; Lloyd M; David M; Sperl G; Pamukcu R; Thompson WJ
J Pharmacol Exp Ther; 2001 Nov; 299(2):583-92. PubMed ID: 11602670
[TBL] [Abstract][Full Text] [Related]
5. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G.
Deguchi A; Soh JW; Li H; Pamukcu R; Thompson WJ; Weinstein IB
Mol Cancer Ther; 2002 Aug; 1(10):803-9. PubMed ID: 12492113
[TBL] [Abstract][Full Text] [Related]
6. Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines.
Lim JT; Piazza GA; Han EK; Delohery TM; Li H; Finn TS; Buttyan R; Yamamoto H; Sperl GJ; Brendel K; Gross PH; Pamukcu R; Weinstein IB
Biochem Pharmacol; 1999 Oct; 58(7):1097-107. PubMed ID: 10484067
[TBL] [Abstract][Full Text] [Related]
7. Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
Moon EY; Lerner A
Cancer Res; 2002 Oct; 62(20):5711-9. PubMed ID: 12384529
[TBL] [Abstract][Full Text] [Related]
8. Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous carcinoma cells.
Joe AK; Liu H; Xiao D; Soh JW; Pinto JT; Beer DG; Piazza GA; Thompson WJ; Weinstein IB
J Exp Ther Oncol; 2003; 3(2):83-94. PubMed ID: 12822514
[TBL] [Abstract][Full Text] [Related]
9. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation.
Li H; Liu L; David ML; Whitehead CM; Chen M; Fetter JR; Sperl GJ; Pamukcu R; Thompson WJ
Biochem Pharmacol; 2002 Nov; 64(9):1325-36. PubMed ID: 12392815
[TBL] [Abstract][Full Text] [Related]
10. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
Soh JW; Mao Y; Kim MG; Pamukcu R; Li H; Piazza GA; Thompson WJ; Weinstein IB
Clin Cancer Res; 2000 Oct; 6(10):4136-41. PubMed ID: 11051267
[TBL] [Abstract][Full Text] [Related]
11. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
Cancer Res; 2000 Jul; 60(13):3338-42. PubMed ID: 10910034
[TBL] [Abstract][Full Text] [Related]
12. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.
Tinsley HN; Gary BD; Keeton AB; Zhang W; Abadi AH; Reynolds RC; Piazza GA
Mol Cancer Ther; 2009 Dec; 8(12):3331-40. PubMed ID: 19996273
[TBL] [Abstract][Full Text] [Related]
13. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Pitari GM; Li T; Baksh RI; Waldman SA
Mol Cancer Ther; 2006 May; 5(5):1190-6. PubMed ID: 16731751
[TBL] [Abstract][Full Text] [Related]
14. Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.
Lim JT; Piazza GA; Pamukcu R; Thompson WJ; Weinstein IB
Clin Cancer Res; 2003 Oct; 9(13):4972-82. PubMed ID: 14581372
[TBL] [Abstract][Full Text] [Related]
15. Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships.
Ko WC; Shih CM; Lai YH; Chen JH; Huang HL
Biochem Pharmacol; 2004 Nov; 68(10):2087-94. PubMed ID: 15476679
[TBL] [Abstract][Full Text] [Related]
16. Induction of cyclic AMP and cyclic GMP 3':5'-cyclic nucleotide phosphodiesterase activities in neuroblastoma lines under differentiating conditions.
Giorgi M; Giordano D; Caniglia C; Biagioni S; Augusti-Tocco G
Int J Dev Neurosci; 1997 Jun; 15(3):309-19. PubMed ID: 9253655
[TBL] [Abstract][Full Text] [Related]
17. Multiplicity within cyclic nucleotide phosphodiesterases.
Rybalkin SD; Beavo JA
Biochem Soc Trans; 1996 Nov; 24(4):1005-9. PubMed ID: 8968501
[No Abstract] [Full Text] [Related]
18. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
Deguchi A; Xing SW; Shureiqi I; Yang P; Newman RA; Lippman SM; Feinmark SJ; Oehlen B; Weinstein IB
Cancer Res; 2005 Sep; 65(18):8442-7. PubMed ID: 16166323
[TBL] [Abstract][Full Text] [Related]
19. Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines.
Rahman MA; Dhar DK; Masunaga R; Yamanoi A; Kohno H; Nagasue N
Cancer Res; 2000 Apr; 60(8):2085-9. PubMed ID: 10786664
[TBL] [Abstract][Full Text] [Related]
20. Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.
Whitehead CM; Earle KA; Fetter J; Xu S; Hartman T; Chan DC; Zhao TL; Piazza G; Klein-Szanto AJ; Pamukcu R; Alila H; Bunn PA; Thompson WJ
Mol Cancer Ther; 2003 May; 2(5):479-88. PubMed ID: 12748310
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
