BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 12477357)

  • 1. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-D-Phe-Arg-Trp-NH2 at the mouse melanocortin receptors. 4. Modifications at the Trp position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    J Med Chem; 2002 Dec; 45(26):5736-44. PubMed ID: 12477357
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jul; 45(14):3073-81. PubMed ID: 12086493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. Part 3: modifications at the Arg position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    Peptides; 2003 Jan; 24(1):73-82. PubMed ID: 12576087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jun; 45(13):2801-10. PubMed ID: 12061882
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of aliphatic, cyclic, and aromatic N-terminally "capped" His-D-Phe-Arg-Trp-NH2 tetrapeptides at the melanocortin receptors.
    Holder JR; Marques FF; Xiang Z; Bauzo RM; Haskell-Luevano C
    Eur J Pharmacol; 2003 Feb; 462(1-3):41-52. PubMed ID: 12591094
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.
    Todorovic A; Holder JR; Bauzo RM; Scott JW; Kavanagh R; Abdel-Malek Z; Haskell-Luevano C
    J Med Chem; 2005 May; 48(9):3328-36. PubMed ID: 15857138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.
    Wilczynski A; Wilson KR; Scott JW; Edison AS; Haskell-Luevano C
    J Med Chem; 2005 Apr; 48(8):3060-75. PubMed ID: 15828845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
    Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD
    J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors.
    Haskell-Luevano C; Holder JR; Monck EK; Bauzo RM
    J Med Chem; 2001 Jun; 44(13):2247-52. PubMed ID: 11405661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity.
    Joseph CG; Wilczynski A; Holder JR; Xiang Z; Bauzo RM; Scott JW; Haskell-Luevano C
    Peptides; 2003 Dec; 24(12):1899-908. PubMed ID: 15127941
    [TBL] [Abstract][Full Text] [Related]  

  • 12. D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity.
    Grieco P; Balse PM; Weinberg D; MacNeil T; Hruby VJ
    J Med Chem; 2000 Dec; 43(26):4998-5002. PubMed ID: 11150170
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
    Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
    J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and activity of the melanocortin Xaa-d-Phe-Arg-Trp-NH tetrapeptides with amide bond modifications.
    Todorovic A; Holder JR; Scott JW; Haskell-Luevano C
    J Pept Res; 2004 Mar; 63(3):270-8. PubMed ID: 15049839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aza-scanning of the potent melanocortin receptor agonist Ac-His-D-Phe-Arg-Trp-NH.
    Boeglin D; Xiang Z; Sorenson NB; Wood MS; Haskell-Luevano C; Lubell WD
    Chem Biol Drug Des; 2006 Apr; 67(4):275-83. PubMed ID: 16629825
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions.
    Haskell-Luevano C; Lim S; Yuan W; Cone RD; Hruby VJ
    Peptides; 2000 Jan; 21(1):49-57. PubMed ID: 10704719
    [TBL] [Abstract][Full Text] [Related]  

  • 17. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
    Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ
    J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
    J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His-dPhe-Arg-Trp-NH
    Todorovic A; Lensing CJ; Holder JR; Scott JW; Sorensen NB; Haskell-Luevano C
    ACS Chem Neurosci; 2018 Nov; 9(11):2753-2766. PubMed ID: 29783840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
    Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
    J Med Chem; 2003 Aug; 46(17):3728-33. PubMed ID: 12904077
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.