These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 12477776)

  • 1. Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine.
    Kaskas BA; Louis E; Hindorf U; Schaeffeler E; Deflandre J; Graepler F; Schmiegelow K; Gregor M; Zanger UM; Eichelbaum M; Schwab M
    Gut; 2003 Jan; 52(1):140-2. PubMed ID: 12477776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Choice of azathioprine or 6-mercaptopurine dose based on thiopurine methyltransferase (TPMT) activity to avoid myelosuppression. A prospective study.
    Gisbert JP; Luna M; Maté J; González-Guijarro L; Cara C; Pajares JM
    Hepatogastroenterology; 2006; 53(69):399-404. PubMed ID: 16795981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine.
    Dilger K; Schaeffeler E; Lukas M; Strauch U; Herfarth H; Müller R; Schwab M
    Ther Drug Monit; 2007 Feb; 29(1):1-5. PubMed ID: 17304143
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease.
    Regueiro M; Mardini H
    J Clin Gastroenterol; 2002 Sep; 35(3):240-4. PubMed ID: 12192200
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease.
    Hindorf U; Lindqvist M; Peterson C; Söderkvist P; Ström M; Hjortswang H; Pousette A; Almer S
    Gut; 2006 Oct; 55(10):1423-31. PubMed ID: 16543290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.
    Wong DR; Pierik M; Seinen ML; van Bodegraven AA; Gilissen LP; Bus P; Bakker JA; Masclee AA; Neef C; Engels LG; Hooymans PM
    J Crohns Colitis; 2014 Feb; 8(2):120-8. PubMed ID: 23932783
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Initiating azathioprine for Crohn's disease.
    Levesque BG; Loftus EV
    Clin Gastroenterol Hepatol; 2012 May; 10(5):460-5. PubMed ID: 22330233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.
    Coenen MJ; de Jong DJ; van Marrewijk CJ; Derijks LJ; Vermeulen SH; Wong DR; Klungel OH; Verbeek AL; Hooymans PM; Peters WH; te Morsche RH; Newman WG; Scheffer H; Guchelaar HJ; Franke B;
    Gastroenterology; 2015 Oct; 149(4):907-17.e7. PubMed ID: 26072396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thiopurines in the Management of Crohn's Disease: Safety and Efficacy Profile in Patients with Normal TPMT Activity-A Retrospective Study.
    Benmassaoud A; Xie X; AlYafi M; Theoret Y; Bitton A; Afif W; Bessissow T
    Can J Gastroenterol Hepatol; 2016; 2016():1034834. PubMed ID: 27446822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.
    Colombel JF; Ferrari N; Debuysere H; Marteau P; Gendre JP; Bonaz B; Soulé JC; Modigliani R; Touze Y; Catala P; Libersa C; Broly F
    Gastroenterology; 2000 Jun; 118(6):1025-30. PubMed ID: 10833476
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine.
    Dubinsky MC; Reyes E; Ofman J; Chiou CF; Wade S; Sandborn WJ
    Am J Gastroenterol; 2005 Oct; 100(10):2239-47. PubMed ID: 16181376
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis.
    Hibi T; Naganuma M; Kitahora T; Kinjyo F; Shimoyama T
    J Gastroenterol; 2003; 38(8):740-6. PubMed ID: 14505127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Optimising azathioprine treatment: determination of thiopurine methyltransferase activity and thiopurine metabolites].
    Alvarez Beltran M; Infante Pina D; Tormo Carnicé R; Segarra Cantón O; Redecillas Ferreiro S
    An Pediatr (Barc); 2009 Feb; 70(2):126-31. PubMed ID: 19217567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two cases of thiopurine methyltransferase (TPMT) deficiency--a lucky save and a near miss with azathioprine.
    Gardiner SJ; Gearry RB; Barclay ML; Begg EJ
    Br J Clin Pharmacol; 2006 Oct; 62(4):473-6. PubMed ID: 16995868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.
    von Ahsen N; Armstrong VW; Behrens C; von Tirpitz C; Stallmach A; Herfarth H; Stein J; Bias P; Adler G; Shipkova M; Oellerich M; Kruis W; Reinshagen M; Schütz E
    Clin Chem; 2005 Dec; 51(12):2282-8. PubMed ID: 16214825
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TPMT in the treatment of Crohn's disease with azathioprine.
    Lennard L
    Gut; 2002 Aug; 51(2):143-6. PubMed ID: 12117866
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.
    Schwab M; Schäffeler E; Marx C; Fischer C; Lang T; Behrens C; Gregor M; Eichelbaum M; Zanger UM; Kaskas BA
    Pharmacogenetics; 2002 Aug; 12(6):429-36. PubMed ID: 12172211
    [TBL] [Abstract][Full Text] [Related]  

  • 18. How are Azathioprine and 6-mercaptopurine dosed by gastroenterologists? Results of a survey of clinical practice.
    Yip JS; Woodward M; Abreu MT; Sparrow MP
    Inflamm Bowel Dis; 2008 Apr; 14(4):514-8. PubMed ID: 18088072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.
    Evans WE; Hon YY; Bomgaars L; Coutre S; Holdsworth M; Janco R; Kalwinsky D; Keller F; Khatib Z; Margolin J; Murray J; Quinn J; Ravindranath Y; Ritchey K; Roberts W; Rogers ZR; Schiff D; Steuber C; Tucci F; Kornegay N; Krynetski EY; Relling MV
    J Clin Oncol; 2001 Apr; 19(8):2293-301. PubMed ID: 11304783
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Azathioprine-associated acute myeloid leukemia in a patient with Crohn's disease and thiopurine S-methyltransferase deficiency.
    Yenson PR; Forrest D; Schmiegelow K; Dalal BI
    Am J Hematol; 2008 Jan; 83(1):80-3. PubMed ID: 17696202
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.