BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

488 related articles for article (PubMed ID: 12478472)

  • 1. Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.
    Gatti L; Supino R; Perego P; Pavesi R; Caserini C; Carenini N; Righetti SC; Zuco V; Zunino F
    Cell Death Differ; 2002 Dec; 9(12):1352-9. PubMed ID: 12478472
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL; Schornagel QC; Tente R; Macpherson JS; Aird RE; Guichard S; Habtemariam A; Sadler P; Jodrell DI
    Cancer Chemother Pharmacol; 2005 Jun; 55(6):577-83. PubMed ID: 15726367
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells.
    Benassi MS; Chiechi A; Ponticelli F; Pazzaglia L; Gamberi G; Zanella L; Manara MC; Perego P; Ferrari S; Picci P
    Cancer Lett; 2007 Jun; 250(2):194-205. PubMed ID: 17113707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV).
    Hagopian GS; Mills GB; Khokhar AR; Bast RC; Siddik ZH
    Clin Cancer Res; 1999 Mar; 5(3):655-63. PubMed ID: 10100719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
    Denko NC; Green SL; Edwards D; Giaccia AJ
    Exp Cell Res; 2000 Jul; 258(1):82-91. PubMed ID: 10912790
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation.
    Shono T; Tofilon PJ; Schaefer TS; Parikh D; Liu TJ; Lang FF
    Cancer Res; 2002 Feb; 62(4):1069-76. PubMed ID: 11861384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation of nuclear Bax/p53 complexes is associated with chemotherapy induced apoptosis.
    Raffo AJ; Kim AL; Fine RL
    Oncogene; 2000 Dec; 19(54):6216-28. PubMed ID: 11175336
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Levels of p53 in Epstein-Barr virus-infected cells determine cell fate: apoptosis, cell cycle arrest at the G1/S boundary without apoptosis, cell cycle arrest at the G2/M boundary without apoptosis, or unrestricted proliferation.
    Chen W; Huang S; Cooper NR
    Virology; 1998 Nov; 251(2):217-26. PubMed ID: 9837785
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
    Hsu YL; Cho CY; Kuo PL; Huang YT; Lin CC
    J Pharmacol Exp Ther; 2006 Aug; 318(2):484-94. PubMed ID: 16632641
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis.
    Janson W; Brandner G; Siegel J
    Oncogene; 1997 Sep; 15(12):1395-406. PubMed ID: 9333015
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells.
    Baptiste N; Friedlander P; Chen X; Prives C
    Oncogene; 2002 Jan; 21(1):9-21. PubMed ID: 11791172
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-181a and miR-630 regulate cisplatin-induced cancer cell death.
    Galluzzi L; Morselli E; Vitale I; Kepp O; Senovilla L; Criollo A; Servant N; Paccard C; Hupé P; Robert T; Ripoche H; Lazar V; Harel-Bellan A; Dessen P; Barillot E; Kroemer G
    Cancer Res; 2010 Mar; 70(5):1793-803. PubMed ID: 20145152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.
    Di Stefano V; Soddu S; Sacchi A; D'Orazi G
    Oncogene; 2005 Aug; 24(35):5431-42. PubMed ID: 15897882
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
    Hill R; Leidal AM; Madureira PA; Gillis LD; Cochrane HK; Waisman DM; Chiu A; Lee PW
    DNA Repair (Amst); 2008 Feb; 7(2):239-52. PubMed ID: 18024214
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog.
    Mujoo K; Watanabe M; Khokhar AR; Siddik ZH
    Prostate; 2005 Jan; 62(1):91-100. PubMed ID: 15389812
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin.
    O'Neill CF; Koberle B; Masters JR; Kelland LR
    Br J Cancer; 1999 Dec; 81(8):1294-303. PubMed ID: 10604725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells.
    Zhou M; Gu L; Li F; Zhu Y; Woods WG; Findley HW
    J Pharmacol Exp Ther; 2002 Oct; 303(1):124-31. PubMed ID: 12235242
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human bladder cancer cells undergo cisplatin-induced apoptosis that is associated with p53-dependent and p53-independent responses.
    Konstantakou EG; Voutsinas GE; Karkoulis PK; Aravantinos G; Margaritis LH; Stravopodis DJ
    Int J Oncol; 2009 Aug; 35(2):401-16. PubMed ID: 19578756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Caffeine induces G2/M arrest and apoptosis via a novel p53-dependent pathway in NB4 promyelocytic leukemia cells.
    Ito K; Nakazato T; Miyakawa Y; Yamato K; Ikeda Y; Kizaki M
    J Cell Physiol; 2003 Aug; 196(2):276-83. PubMed ID: 12811820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress.
    Li J; Tan J; Zhuang L; Banerjee B; Yang X; Chau JF; Lee PL; Hande MP; Li B; Yu Q
    Cancer Res; 2007 Dec; 67(23):11317-26. PubMed ID: 18056458
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.