These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
410 related articles for article (PubMed ID: 12482990)
1. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Itahana K; Zou Y; Itahana Y; Martinez JL; Beausejour C; Jacobs JJ; Van Lohuizen M; Band V; Campisi J; Dimri GP Mol Cell Biol; 2003 Jan; 23(1):389-401. PubMed ID: 12482990 [TBL] [Abstract][Full Text] [Related]
2. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Rheinwald JG; Hahn WC; Ramsey MR; Wu JY; Guo Z; Tsao H; De Luca M; Catricalà C; O'Toole KM Mol Cell Biol; 2002 Jul; 22(14):5157-72. PubMed ID: 12077343 [TBL] [Abstract][Full Text] [Related]
3. Expression profiles of p53-, p16(INK4a)-, and telomere-regulating genes in replicative senescent primary human, mouse, and chicken fibroblast cells. Kim H; You S; Farris J; Kong BW; Christman SA; Foster LK; Foster DN Exp Cell Res; 2002 Jan; 272(2):199-208. PubMed ID: 11777345 [TBL] [Abstract][Full Text] [Related]
4. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms. Davis T; Singhrao SK; Wyllie FS; Haughton MF; Smith PJ; Wiltshire M; Wynford-Thomas D; Jones CJ; Faragher RG; Kipling D J Cell Sci; 2003 Apr; 116(Pt 7):1349-57. PubMed ID: 12615976 [TBL] [Abstract][Full Text] [Related]
5. Contribution of p16(INK4a) to replicative senescence of human fibroblasts. Brookes S; Rowe J; Gutierrez Del Arroyo A; Bond J; Peters G Exp Cell Res; 2004 Aug; 298(2):549-59. PubMed ID: 15265701 [TBL] [Abstract][Full Text] [Related]
6. Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS. Klimova TA; Bell EL; Shroff EH; Weinberg FD; Snyder CM; Dimri GP; Schumacker PT; Budinger GR; Chandel NS FASEB J; 2009 Mar; 23(3):783-94. PubMed ID: 18948382 [TBL] [Abstract][Full Text] [Related]
7. Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT. Haga K; Ohno S; Yugawa T; Narisawa-Saito M; Fujita M; Sakamoto M; Galloway DA; Kiyono T Cancer Sci; 2007 Feb; 98(2):147-54. PubMed ID: 17233832 [TBL] [Abstract][Full Text] [Related]
9. Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence. Agherbi H; Gaussmann-Wenger A; Verthuy C; Chasson L; Serrano M; Djabali M PLoS One; 2009 May; 4(5):e5622. PubMed ID: 19462008 [TBL] [Abstract][Full Text] [Related]
10. Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. Wei W; Herbig U; Wei S; Dutriaux A; Sedivy JM EMBO Rep; 2003 Nov; 4(11):1061-6. PubMed ID: 14566323 [TBL] [Abstract][Full Text] [Related]
11. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Dickson MA; Hahn WC; Ino Y; Ronfard V; Wu JY; Weinberg RA; Louis DN; Li FP; Rheinwald JG Mol Cell Biol; 2000 Feb; 20(4):1436-47. PubMed ID: 10648628 [TBL] [Abstract][Full Text] [Related]
13. Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock. Munro J; Barr NI; Ireland H; Morrison V; Parkinson EK Exp Cell Res; 2004 May; 295(2):525-38. PubMed ID: 15093749 [TBL] [Abstract][Full Text] [Related]
14. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1. Negishi M; Saraya A; Mochizuki S; Helin K; Koseki H; Iwama A PLoS One; 2010 Aug; 5(8):e12373. PubMed ID: 20808772 [TBL] [Abstract][Full Text] [Related]
15. Polycomb CBX7 has a unifying role in cellular lifespan. Gil J; Bernard D; Martínez D; Beach D Nat Cell Biol; 2004 Jan; 6(1):67-72. PubMed ID: 14647293 [TBL] [Abstract][Full Text] [Related]
16. E2FBP1 antagonizes the p16(INK4A)-Rb tumor suppressor machinery for growth suppression and cellular senescence by regulating promyelocytic leukemia protein stability. Fukuyo Y; Takahashi A; Hara E; Horikoshi N; Pandita TK; Nakajima T Int J Oral Sci; 2011 Oct; 3(4):200-8. PubMed ID: 22010578 [TBL] [Abstract][Full Text] [Related]
17. Retinoic acid extends the in vitro life span of normal human oral keratinocytes by decreasing p16(INK4A) expression and maintaining telomerase activity. You YO; Lee G; Min BM Biochem Biophys Res Commun; 2000 Feb; 268(2):268-74. PubMed ID: 10679192 [TBL] [Abstract][Full Text] [Related]
18. Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF. Kranc KR; Bamforth SD; Bragança J; Norbury C; van Lohuizen M; Bhattacharya S Mol Cell Biol; 2003 Nov; 23(21):7658-66. PubMed ID: 14560011 [TBL] [Abstract][Full Text] [Related]
19. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. Gorbunova V; Seluanov A; Pereira-Smith OM J Biol Chem; 2002 Oct; 277(41):38540-9. PubMed ID: 12140282 [TBL] [Abstract][Full Text] [Related]
20. Mechanisms of cellular senescence in human and mouse cells. Itahana K; Campisi J; Dimri GP Biogerontology; 2004; 5(1):1-10. PubMed ID: 15138376 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]