These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

484 related articles for article (PubMed ID: 12486003)

  • 1. In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.
    Matsuyama A; Shimazu T; Sumida Y; Saito A; Yoshimatsu Y; Seigneurin-Berny D; Osada H; Komatsu Y; Nishino N; Khochbin S; Horinouchi S; Yoshida M
    EMBO J; 2002 Dec; 21(24):6820-31. PubMed ID: 12486003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HDAC6 is a microtubule-associated deacetylase.
    Hubbert C; Guardiola A; Shao R; Kawaguchi Y; Ito A; Nixon A; Yoshida M; Wang XF; Yao TP
    Nature; 2002 May; 417(6887):455-8. PubMed ID: 12024216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cells.
    Asthana J; Kapoor S; Mohan R; Panda D
    J Biol Chem; 2013 Aug; 288(31):22516-26. PubMed ID: 23798680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation.
    Nam HJ; Kang JK; Kim SK; Ahn KJ; Seok H; Park SJ; Chang JS; Pothoulakis C; Lamont JT; Kim H
    J Biol Chem; 2010 Oct; 285(43):32888-32896. PubMed ID: 20696758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase 6 (HDAC6) is an independent deacetylase for alpha-tubulin.
    Zhao Z; Xu H; Gong W
    Protein Pept Lett; 2010 May; 17(5):555-8. PubMed ID: 19961433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microtubule stabilization by Mdp3 is partially attributed to its modulation of HDAC6 in addition to its association with tubulin and microtubules.
    Tala ; Sun X; Chen J; Zhang L; Liu N; Zhou J; Li D; Liu M
    PLoS One; 2014; 9(3):e90932. PubMed ID: 24614595
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation.
    Haggarty SJ; Koeller KM; Wong JC; Grozinger CM; Schreiber SL
    Proc Natl Acad Sci U S A; 2003 Apr; 100(8):4389-94. PubMed ID: 12677000
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation.
    Zhang D; Wu CT; Qi X; Meijering RA; Hoogstra-Berends F; Tadevosyan A; Cubukcuoglu Deniz G; Durdu S; Akar AR; Sibon OC; Nattel S; Henning RH; Brundel BJ
    Circulation; 2014 Jan; 129(3):346-58. PubMed ID: 24146251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function.
    Shepard BD; Joseph RA; Kannarkat GT; Rutledge TM; Tuma DJ; Tuma PL
    Hepatology; 2008 Nov; 48(5):1671-9. PubMed ID: 18697214
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6.
    Skoge RH; Ziegler M
    J Cell Sci; 2016 Aug; 129(15):2972-82. PubMed ID: 27311481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes.
    Noack M; Leyk J; Richter-Landsberg C
    Glia; 2014 Apr; 62(4):535-47. PubMed ID: 24464872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
    Zilberman Y; Ballestrem C; Carramusa L; Mazitschek R; Khochbin S; Bershadsky A
    J Cell Sci; 2009 Oct; 122(Pt 19):3531-41. PubMed ID: 19737819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally.
    Zhang Y; Kwon S; Yamaguchi T; Cubizolles F; Rousseaux S; Kneissel M; Cao C; Li N; Cheng HL; Chua K; Lombard D; Mizeracki A; Matthias G; Alt FW; Khochbin S; Matthias P
    Mol Cell Biol; 2008 Mar; 28(5):1688-701. PubMed ID: 18180281
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases.
    Brush MH; Guardiola A; Connor JH; Yao TP; Shenolikar S
    J Biol Chem; 2004 Feb; 279(9):7685-91. PubMed ID: 14670976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dysferlin interacts with histone deacetylase 6 and increases alpha-tubulin acetylation.
    Di Fulvio S; Azakir BA; Therrien C; Sinnreich M
    PLoS One; 2011; 6(12):e28563. PubMed ID: 22174839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural insights into HDAC6 tubulin deacetylation and its selective inhibition.
    Miyake Y; Keusch JJ; Wang L; Saito M; Hess D; Wang X; Melancon BJ; Helquist P; Gut H; Matthias P
    Nat Chem Biol; 2016 Sep; 12(9):748-54. PubMed ID: 27454931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MeCP2 deficiency is associated with reduced levels of tubulin acetylation and can be restored using HDAC6 inhibitors.
    Gold WA; Lacina TA; Cantrill LC; Christodoulou J
    J Mol Med (Berl); 2015 Jan; 93(1):63-72. PubMed ID: 25209898
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry.
    Liu N; Xiong Y; Li S; Ren Y; He Q; Gao S; Zhou J; Shui W
    Sci Rep; 2015 Nov; 5():16869. PubMed ID: 26581825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules.
    Skultetyova L; Ustinova K; Kutil Z; Novakova Z; Pavlicek J; Mikesova J; Trapl D; Baranova P; Havlinova B; Hubalek M; Lansky Z; Barinka C
    Sci Rep; 2017 Sep; 7(1):11547. PubMed ID: 28912522
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction.
    Wattanathamsan O; Chantaravisoot N; Wongkongkathep P; Kungsukool S; Chetprayoon P; Chanvorachote P; Vinayanuwattikun C; Pongrakhananon V
    J Biomed Sci; 2023 Jan; 30(1):4. PubMed ID: 36639650
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.