These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 12486085)

  • 1. Evaluation of thymidylate synthase protein expression by Western blotting and immunohistochemistry on human colon carcinoma xenografts in nude mice.
    Derenzini M; Montanaro L; Chillà A; Tosti E; Ceccarelli C; Dall'Olio F; Ofner D; Treré D
    J Histochem Cytochem; 2002 Dec; 50(12):1633-40. PubMed ID: 12486085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue.
    Johnston PG; Liang CM; Henry S; Chabner BA; Allegra CJ
    Cancer Res; 1991 Dec; 51(24):6668-76. PubMed ID: 1720706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.
    Johnston PG; Drake JC; Trepel J; Allegra CJ
    Cancer Res; 1992 Aug; 52(16):4306-12. PubMed ID: 1643628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
    Houghton PJ; Rahman A; Will CL; Dolnick BJ; Houghton JA
    Cancer Res; 1992 Feb; 52(3):558-65. PubMed ID: 1732043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization and drug sensitivity of four newly established colon adenocarcinoma cell lines to antifolate inhibitors of thymidylate synthase.
    Longo GS; Izzo J; Gorlick R; Banerjee D; Jhanwar SC; Bertino JR
    Oncol Res; 2001; 12(8):309-14. PubMed ID: 11589301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epitope analysis and utility of monoclonal antibodies to native and recombinant human thymidylate synthase.
    Okabe H; Koizumi K; Tsujimoto H; Fukushima M
    Int J Mol Med; 2000 Feb; 5(2):133-8. PubMed ID: 10639590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site.
    Lenz HJ; Danenberg KD; Leichman CG; Florentine B; Johnston PG; Groshen S; Zhou L; Xiong YP; Danenberg PV; Leichman LP
    Clin Cancer Res; 1998 May; 4(5):1227-34. PubMed ID: 9607581
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thymidylate synthase genotyping is more predictive for therapy response than immunohistochemistry in patients with colon cancer.
    Gosens MJ; Moerland E; Lemmens VP; Rutten HT; Tan-Go I; van den Brule AJ
    Int J Cancer; 2008 Oct; 123(8):1941-9. PubMed ID: 18661526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
    Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
    Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.
    Kadota K; Huang CL; Liu D; Yokomise H; Haba R; Wada H
    Int J Oncol; 2011 Feb; 38(2):355-63. PubMed ID: 21174056
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation.
    Saga Y; Suzuki M; Mizukami H; Urabe M; Fukushima M; Ozawa K; Sato I
    Oncology; 2002; 63(2):185-91. PubMed ID: 12239455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
    Yawata A; Kim SR; Miyajima A; Kubo T; Ishida S; Saito Y; Nakajima Y; Katori N; Matsumoto Y; Fukuoka M; Ohno Y; Ozawa S; Sawada J
    Cancer Chemother Pharmacol; 2005 Nov; 56(5):465-72. PubMed ID: 15918040
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dihydropyrimidine dehydrogenase activity and messenger RNA level may be related to the antitumor effect of 5-fluorouracil on human tumor xenografts in nude mice.
    Ishikawa Y; Kubota T; Otani Y; Watanabe M; Teramoto T; Kumai K; Kitajima M; Takechi T; Okabe H; Fukushima M
    Clin Cancer Res; 1999 Apr; 5(4):883-9. PubMed ID: 10213225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of cepharanthine alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice.
    Harada K; Ferdous T; Itashiki Y; Takii M; Mano T; Mori Y; Ueyama Y
    Anticancer Res; 2009 Apr; 29(4):1263-70. PubMed ID: 19414373
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.
    Houghton PJ; Germain GS; Hazelton BJ; Pennington JW; Houghton JA
    Proc Natl Acad Sci U S A; 1989 Feb; 86(4):1377-81. PubMed ID: 2537495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody.
    Van Triest B; Loftus BM; Pinedo HM; Backus HH; Schoenmakers P; Telleman F; Tadema T; Aherne GW; Van Groeningen CJ; Zoetmulder FA; Taal BG; Johnston PG; Peters GJ
    J Histochem Cytochem; 2000 Jun; 48(6):755-60. PubMed ID: 10820149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines.
    McGinn CJ; Pestalozzi BC; Drake JC; Glennon MC; Kunugi K; Otterson G; Allegra CJ; Johnston PG; Kinsella TJ
    Cancer J; 2000; 6(4):234-42. PubMed ID: 11038143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [The correlation between thymidylate synthase expression and cytotoxicity of 5-fluorouracil in human cancer cell lines: study using polyclonal antibody against recombinant human thymidylate synthase].
    Okabe H; Tsujimoto H; Fukushima M
    Gan To Kagaku Ryoho; 1997 Apr; 24(6):705-12. PubMed ID: 9126308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of thymidylate synthase, orotate phosphoribosyltransferase and dihydropyrimidine dehydrogenase in thymic epithelial tumors.
    Kaira K; Serizawa M; Koh Y; Miura S; Kaira R; Abe M; Nakagawa K; Ohde Y; Okumura T; Murakami H; Tsuya A; Nakamura Y; Naito T; Takahashi T; Kondo H; Nakajima T; Endo M; Yamamoto N
    Lung Cancer; 2011 Dec; 74(3):419-25. PubMed ID: 21550686
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.