BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 12486127)

  • 1. Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity.
    Tong J; Elowe S; Nash P; Pawson T
    J Biol Chem; 2003 Feb; 278(8):6111-9. PubMed ID: 12486127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction.
    Elowe S; Holland SJ; Kulkarni S; Pawson T
    Mol Cell Biol; 2001 Nov; 21(21):7429-41. PubMed ID: 11585923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.
    Holland SJ; Gale NW; Gish GD; Roth RA; Songyang Z; Cantley LC; Henkemeyer M; Yancopoulos GD; Pawson T
    EMBO J; 1997 Jul; 16(13):3877-88. PubMed ID: 9233798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2.
    Wagner MJ; Hsiung MS; Gish GD; Bagshaw RD; Doodnauth SA; Soliman MA; Jørgensen C; Tucholska M; Rottapel R
    J Biol Chem; 2020 Mar; 295(12):3932-3944. PubMed ID: 32060095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses.
    Zisch AH; Pazzagli C; Freeman AL; Schneller M; Hadman M; Smith JW; Ruoslahti E; Pasquale EB
    Oncogene; 2000 Jan; 19(2):177-87. PubMed ID: 10644995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor.
    Yu HH; Zisch AH; Dodelet VC; Pasquale EB
    Oncogene; 2001 Jul; 20(30):3995-4006. PubMed ID: 11494128
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.
    Zisch AH; Kalo MS; Chong LD; Pasquale EB
    Oncogene; 1998 May; 16(20):2657-70. PubMed ID: 9632142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.
    Himanen JP; Chumley MJ; Lackmann M; Li C; Barton WA; Jeffrey PD; Vearing C; Geleick D; Feldheim DA; Boyd AW; Henkemeyer M; Nikolov DB
    Nat Neurosci; 2004 May; 7(5):501-9. PubMed ID: 15107857
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple in vivo tyrosine phosphorylation sites in EphB receptors.
    Kalo MS; Pasquale EB
    Biochemistry; 1999 Oct; 38(43):14396-408. PubMed ID: 10572014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway.
    Poliakov A; Cotrina ML; Pasini A; Wilkinson DG
    J Cell Biol; 2008 Dec; 183(5):933-47. PubMed ID: 19047466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB; Royer AR; Middlemas DS
    J Neurochem; 2006 May; 97(3):834-45. PubMed ID: 16573649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases.
    Honma M; Higuchi O; Shirakata M; Yasuda T; Shibuya H; Iemura S; Natsume T; Yamanashi Y
    Genes Cells; 2006 Feb; 11(2):143-51. PubMed ID: 16436051
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.
    Wybenga-Groot LE; Baskin B; Ong SH; Tong J; Pawson T; Sicheri F
    Cell; 2001 Sep; 106(6):745-57. PubMed ID: 11572780
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue.
    Kalo MS; Yu HH; Pasquale EB
    J Biol Chem; 2001 Oct; 276(42):38940-8. PubMed ID: 11466320
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling.
    Li S; Couvillon AD; Brasher BB; Van Etten RA
    EMBO J; 2001 Dec; 20(23):6793-804. PubMed ID: 11726515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation.
    Jones N; Dumont DJ
    Curr Biol; 1999 Sep; 9(18):1057-60. PubMed ID: 10508618
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells.
    Kim I; Ryu YS; Kwak HJ; Ahn SY; Oh JL; Yancopoulos GD; Gale NW; Koh GY
    FASEB J; 2002 Jul; 16(9):1126-8. PubMed ID: 12039842
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation.
    Montagner A; Yart A; Dance M; Perret B; Salles JP; Raynal P
    J Biol Chem; 2005 Feb; 280(7):5350-60. PubMed ID: 15574420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.
    Hock B; Böhme B; Karn T; Yamamoto T; Kaibuchi K; Holtrich U; Holland S; Pawson T; Rübsamen-Waigmann H; Strebhardt K
    Proc Natl Acad Sci U S A; 1998 Aug; 95(17):9779-84. PubMed ID: 9707552
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
    Xu Y; Robev D; Saha N; Wang B; Dalva MB; Xu K; Himanen JP; Nikolov DB
    Int J Mol Sci; 2021 Sep; 22(19):. PubMed ID: 34638814
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.