These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 12488357)

  • 1. Trafficking of mutant carboxypeptidase E to secretory granules in a beta-cell line derived from Cpe(fat)/Cpe(fat) mice.
    Cawley NX; Rodriguez YM; Maldonado A; Loh YP
    Endocrinology; 2003 Jan; 144(1):292-8. PubMed ID: 12488357
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing.
    Varlamov O; Fricker LD; Furukawa H; Steiner DF; Langley SH; Leiter EH
    Endocrinology; 1997 Nov; 138(11):4883-92. PubMed ID: 9348219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The sorting of proglucagon to secretory granules is mediated by carboxypeptidase E and intrinsic sorting signals.
    McGirr R; Guizzetti L; Dhanvantari S
    J Endocrinol; 2013 May; 217(2):229-40. PubMed ID: 23418362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Depletion of carboxypeptidase E, a regulated secretory pathway sorting receptor, causes misrouting and constitutive secretion of proinsulin and proenkephalin, but not chromogranin A.
    Normant E; Loh YP
    Endocrinology; 1998 Apr; 139(4):2137-45. PubMed ID: 9529003
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Processing of procarboxypeptidase E into carboxypeptidase E occurs in secretory vesicles.
    Song L; Fricker L
    J Neurochem; 1995 Jul; 65(1):444-53. PubMed ID: 7790890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induced and spontaneous mutations at Ser202 of carboxypeptidase E. Effect on enzyme expression, activity, and intracellular routing.
    Varlamov O; Leiter EH; Fricker L
    J Biol Chem; 1996 Jun; 271(24):13981-6. PubMed ID: 8662840
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
    Naggert JK; Fricker LD; Varlamov O; Nishina PM; Rouille Y; Steiner DF; Carroll RJ; Paigen BJ; Leiter EH
    Nat Genet; 1995 Jun; 10(2):135-42. PubMed ID: 7663508
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular heterogeneity and cellular localization of carboxypeptidase H in the islets of Langerhans.
    Guest PC; Ravazzola M; Davidson HW; Orci L; Hutton JC
    Endocrinology; 1991 Aug; 129(2):734-40. PubMed ID: 1855471
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a novel prohormone sorting signal-binding site on carboxypeptidase E, a regulated secretory pathway-sorting receptor.
    Zhang CF; Snell CR; Loh YP
    Mol Endocrinol; 1999 Apr; 13(4):527-36. PubMed ID: 10194759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice.
    Berman Y; Mzhavia N; Polonskaia A; Devi LA
    J Biol Chem; 2001 Jan; 276(2):1466-73. PubMed ID: 11038363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Posttranslational processing of carboxypeptidase E, a neuropeptide-processing enzyme, in AtT-20 cells and bovine pituitary secretory granules.
    Fricker LD; Devi L
    J Neurochem; 1993 Oct; 61(4):1404-15. PubMed ID: 8376994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts.
    Zhang CF; Dhanvantari S; Lou H; Loh YP
    Biochem J; 2003 Feb; 369(Pt 3):453-60. PubMed ID: 12403651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells.
    Chu KY; Briggs MJ; Albrecht T; Drain PF; Johnson JD
    Islets; 2011; 3(4):155-65. PubMed ID: 21628999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice.
    Cool DR; Normant E; Shen F; Chen HC; Pannell L; Zhang Y; Loh YP
    Cell; 1997 Jan; 88(1):73-83. PubMed ID: 9019408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice.
    Irminger JC; Verchere CB; Meyer K; Halban PA
    J Biol Chem; 1997 Oct; 272(44):27532-4. PubMed ID: 9346885
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The pro region is not required for the expression or intracellular routeing of carboxypeptidase E.
    Song L; Fricker LD
    Biochem J; 1997 Apr; 323 ( Pt 1)(Pt 1):265-71. PubMed ID: 9173892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glu300 of rat carboxypeptidase E is essential for enzymatic activity but not substrate binding or routing to the regulated secretory pathway.
    Qian Y; Varlamov O; Fricker LD
    J Biol Chem; 1999 Apr; 274(17):11582-6. PubMed ID: 10206965
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cholecystokinin (CCK) levels are greatly reduced in the brains but not the duodenums of Cpe(fat)/Cpe(fat) mice: a regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing.
    Cain BM; Wang W; Beinfeld MC
    Endocrinology; 1997 Sep; 138(9):4034-7. PubMed ID: 9275097
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.
    Marzban L; Soukhatcheva G; Verchere CB
    Endocrinology; 2005 Apr; 146(4):1808-17. PubMed ID: 15618358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered neuropeptide processing in prefrontal cortex of Cpe (fat/fat) mice: implications for neuropeptide discovery.
    Lim J; Berezniuk I; Che FY; Parikh R; Biswas R; Pan H; Fricker LD
    J Neurochem; 2006 Feb; 96(4):1169-81. PubMed ID: 16417576
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.