BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

547 related articles for article (PubMed ID: 12490139)

  • 1. T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD.
    Kerkvliet NI; Shepherd DM; Baecher-Steppan L
    Toxicol Appl Pharmacol; 2002 Dec; 185(2):146-52. PubMed ID: 12490139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of constitutively-active aryl hydrocarbon receptor in T-cells enhances the down-regulation of CD62L, but does not alter expression of CD25 or suppress the allogeneic CTL response.
    Funatake CJ; Ao K; Suzuki T; Murai H; Yamamoto M; Fujii-Kuriyama Y; Kerkvliet NI; Nohara K
    J Immunotoxicol; 2009 Sep; 6(3):194-203. PubMed ID: 19635034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Kerkvliet NI; Baecher-Steppan L; Shepherd DM; Oughton JA; Vorderstrasse BA; DeKrey GK
    J Immunol; 1996 Sep; 157(6):2310-9. PubMed ID: 8805628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T cells toward a regulatory T cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T cells.
    Funatake CJ; Marshall NB; Kerkvliet NI
    J Immunotoxicol; 2008 Jan; 5(1):81-91. PubMed ID: 18382861
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the aryl hydrocarbon receptor diminishes the memory response to homotypic influenza virus infection but does not impair host resistance.
    Lawrence BP; Vorderstrasse BA
    Toxicol Sci; 2004 Jun; 79(2):304-14. PubMed ID: 14976337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hydrocarbon receptor activation in hemopoietic cells.
    Staples JE; Murante FG; Fiore NC; Gasiewicz TA; Silverstone AE
    J Immunol; 1998 Apr; 160(8):3844-54. PubMed ID: 9558089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Marshall NB; Vorachek WR; Steppan LB; Mourich DV; Kerkvliet NI
    J Immunol; 2008 Aug; 181(4):2382-91. PubMed ID: 18684927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway.
    Rohlman D; Punj S; Pennington J; Bradford S; Kerkvliet NI
    Toxicol Sci; 2013 Sep; 135(1):81-90. PubMed ID: 23798565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the aryl hydrocarbon receptor reduces the number of precursor and effector T cells, but preserves thymic CD4+CD25+Foxp3+ regulatory T cells.
    Schulz VJ; Smit JJ; Bol-Schoenmakers M; van Duursen MB; van den Berg M; Pieters RH
    Toxicol Lett; 2012 Nov; 215(2):100-9. PubMed ID: 23041608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2,3,7,8-Tetrachlorodibenzo-p-dioxin prompted differentiation to CD4
    Cho MK; Park JG; Iwata H; Kim EY
    Ecotoxicol Environ Saf; 2021 Mar; 211():111947. PubMed ID: 33503546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of altered B7 expression in dioxin immunotoxicity: B7 transfection restores the CTL but not the autoantibody response to the P815 mastocytoma.
    Prell RA; Kerkvliet NI
    J Immunol; 1997 Mar; 158(6):2695-703. PubMed ID: 9058803
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CTL hyporesponsiveness induced by 2,3,7, 8-tetrachlorodibenzo-p-dioxin: role of cytokines and apoptosis.
    Prell RA; Dearstyne E; Steppan LG; Vella AT; Kerkvliet NI
    Toxicol Appl Pharmacol; 2000 Aug; 166(3):214-21. PubMed ID: 10906285
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells.
    Funatake CJ; Marshall NB; Steppan LB; Mourich DV; Kerkvliet NI
    J Immunol; 2005 Oct; 175(7):4184-8. PubMed ID: 16177056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sensitivity to suppression of cytotoxic T cell generation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the Ah genotype of the murine host.
    Nagarkatti PS; Sweeney GD; Gauldie J; Clark DA
    Toxicol Appl Pharmacol; 1984 Jan; 72(1):169-76. PubMed ID: 6608808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The immunotoxic effects of dual exposure to PCP and TCDD.
    Chen HM; Lee YH; Chen RJ; Chiu HW; Wang BJ; Wang YJ
    Chem Biol Interact; 2013 Nov; 206(2):166-74. PubMed ID: 24051191
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung.
    Lawrence BP; Roberts AD; Neumiller JJ; Cundiff JA; Woodland DL
    J Immunol; 2006 Nov; 177(9):5819-28. PubMed ID: 17056506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse uterus: critical role of the aryl hydrocarbon receptor in stromal tissue.
    Buchanan DL; Sato T; Peterson RE; Cooke PS
    Toxicol Sci; 2000 Oct; 57(2):302-11. PubMed ID: 11006360
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional alterations in CD11b(+)Gr-1(+) cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Choi JY; Oughton JA; Kerkvliet NI
    Int Immunopharmacol; 2003 Apr; 3(4):553-70. PubMed ID: 12689660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of cytotoxic T lymphocyte activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin occurs in vivo, but not in vitro, and is independent of corticosterone elevation.
    De Krey GK; Kerkvliet NI
    Toxicology; 1995 Mar; 97(1-3):105-12. PubMed ID: 7716775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Generation of alphabeta T-cell receptor+ CD4- CD8+ cells in major histocompatibility complex class I-deficient mice upon activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Kronenberg S; Lai Z; Esser C
    Immunology; 2000 Jun; 100(2):185-93. PubMed ID: 10886394
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.