BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 12499384)

  • 1. Isolation and characterization of androgen receptor mutant, AR(M749L), with hypersensitivity to 17-beta estradiol treatment.
    Thin TH; Wang L; Kim E; Collins LL; Basavappa R; Chang C
    J Biol Chem; 2003 Feb; 278(9):7699-708. PubMed ID: 12499384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional analysis of androgen receptor N-terminal and ligand binding domain interacting coregulators in prostate cancer.
    Yeh S; Sampson ER; Lee DK; Kim E; Hsu CL; Chen YL; Chang HC; Altuwaijri S; Huang KE; Chang C
    J Formos Med Assoc; 2000 Dec; 99(12):885-94. PubMed ID: 11155740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells.
    Tan J; Sharief Y; Hamil KG; Gregory CW; Zang DY; Sar M; Gumerlock PH; deVere White RW; Pretlow TG; Harris SE; Wilson EM; Mohler JL; French FS
    Mol Endocrinol; 1997 Apr; 11(4):450-9. PubMed ID: 9092797
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation.
    Thin TH; Kim E; Yeh S; Sampson ER; Chen YT; Collins LL; Basavappa R; Chang C
    J Biol Chem; 2002 Sep; 277(39):36499-508. PubMed ID: 12068007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligand- and coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region.
    Wang Q; Lu J; Yong EL
    J Biol Chem; 2001 Mar; 276(10):7493-9. PubMed ID: 11102454
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional in vivo interaction between the amino-terminal, transactivation domain and the ligand binding domain of the androgen receptor.
    Doesburg P; Kuil CW; Berrevoets CA; Steketee K; Faber PW; Mulder E; Brinkmann AO; Trapman J
    Biochemistry; 1997 Feb; 36(5):1052-64. PubMed ID: 9033395
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains.
    Jääskeläinen J; Deeb A; Schwabe JW; Mongan NP; Martin H; Hughes IA
    J Mol Endocrinol; 2006 Apr; 36(2):361-8. PubMed ID: 16595706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth.
    Miyamoto H; Rahman M; Takatera H; Kang HY; Yeh S; Chang HC; Nishimura K; Fujimoto N; Chang C
    J Biol Chem; 2002 Feb; 277(7):4609-17. PubMed ID: 11673464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and characterization of androgen receptor associated coregulators in prostate cancer cells.
    Sampson ER; Yeh SY; Chang HC; Tsai MY; Wang X; Ting HJ; Chang C
    J Biol Regul Homeost Agents; 2001; 15(2):123-9. PubMed ID: 11501969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.
    Buchanan G; Yang M; Harris JM; Nahm HS; Han G; Moore N; Bentel JM; Matusik RJ; Horsfall DJ; Marshall VR; Greenberg NM; Tilley WD
    Mol Endocrinol; 2001 Jan; 15(1):46-56. PubMed ID: 11145738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A naturally occurring mutation in the human androgen receptor of a subject with complete androgen insensitivity confers binding and transactivation by estradiol.
    Bonagura TW; Deng M; Brown TR
    Mol Cell Endocrinol; 2007 Jan; 263(1-2):79-89. PubMed ID: 17011702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor.
    Wang LG; Liu XM; Kreis W; Budman DR
    Biochem Pharmacol; 1998 May; 55(9):1427-33. PubMed ID: 10076535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities.
    Vivat V; Gofflo D; Garcia T; Wurtz JM; Bourguet W; Philibert D; Gronemeyer H
    J Mol Endocrinol; 1997 Apr; 18(2):147-60. PubMed ID: 9134501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Partial androgen insensitivity and correlations with the predicted three dimensional structure of the androgen receptor ligand-binding domain.
    Yong EL; Tut TG; Ghadessy FJ; Prins G; Ratnam SS
    Mol Cell Endocrinol; 1998 Feb; 137(1):41-50. PubMed ID: 9607727
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isolation and characterization of the androgen receptor mutants with divergent transcriptional activity in response to hydroxyflutamide.
    Wang C; Young WJ; Chang C
    Endocrine; 2000 Feb; 12(1):69-76. PubMed ID: 10855693
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human androgen receptor mutation disrupts ternary interactions between ligand, receptor domains, and the coactivator TIF2 (transcription intermediary factor 2).
    Lim J; Ghadessy FJ; Abdullah AA; Pinsky L; Trifiro M; Yong EL
    Mol Endocrinol; 2000 Aug; 14(8):1187-97. PubMed ID: 10935543
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells.
    Lin HK; Altuwaijri S; Lin WJ; Kan PY; Collins LL; Chang C
    J Biol Chem; 2002 Sep; 277(39):36570-6. PubMed ID: 12119296
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Supervillin associates with androgen receptor and modulates its transcriptional activity.
    Ting HJ; Yeh S; Nishimura K; Chang C
    Proc Natl Acad Sci U S A; 2002 Jan; 99(2):661-6. PubMed ID: 11792840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer.
    Gregory CW; Fei X; Ponguta LA; He B; Bill HM; French FS; Wilson EM
    J Biol Chem; 2004 Feb; 279(8):7119-30. PubMed ID: 14662770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor.
    Chen G; Nomura M; Morinaga H; Matsubara E; Okabe T; Goto K; Yanase T; Zheng H; Lu J; Nawata H
    J Biol Chem; 2005 Oct; 280(43):36355-63. PubMed ID: 16120611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.