BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 12499636)

  • 1. Humanization of the mouse anti-Fas antibody HFE7A and crystal structure of the humanized HFE7A Fab fragment.
    Haruyama H; Ito S; Miyadai K; Takahashi T; Kawaida R; Takayama T; Hanzawa H; Hata T; Yamaguchi J; Yoshida-Kato H; Ichikawa K; Ohsumi J; Yonehara S; Serizawa N
    Biol Pharm Bull; 2002 Dec; 25(12):1537-45. PubMed ID: 12499636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of the antigen-binding fragment of apoptosis-inducing mouse anti-human Fas monoclonal antibody HFE7A.
    Ito S; Takayama T; Hanzawa H; Ichikawa K; Ohsumi J; Serizawa N; Hata T; Haruyama H
    J Biochem; 2002 Jan; 131(1):137-43. PubMed ID: 11754745
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallization and preliminary X-ray crystallographic studies on a Fab fragment of the mouse anti-human Fas monoclonal antibody HFE7A.
    Ito S; Takayama T; Hanzawa H; Ichikawa K; Ohsumi J; Serizawa N; Haruyama H; Hata T
    Acta Crystallogr D Biol Crystallogr; 2001 Nov; 57(Pt 11):1700-2. PubMed ID: 11679750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning and expression of a novel murine anti-human Fas antibody.
    Yoshida-Kato H; Ichikawa K; Yamaguchi J; Watanabe K; Ohsumi J; Yonehara S; Serizawa N
    Biosci Biotechnol Biochem; 2000 Sep; 64(9):1903-8. PubMed ID: 11055394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystallization and preliminary x-ray studies of the Fab fragment from a humanized version of the mouse anti-human fas antibody HFE7a.
    Ito S; Takayama T; Hanzawa H; Takahashi T; Miyadai K; Serizawa N; Haruyama H; Hata T
    Protein Pept Lett; 2002 Jun; 9(3):259-63. PubMed ID: 12144523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antirheumatic effects of humanized anti-Fas monoclonal antibody in human rheumatoid arthritis/SCID mouse chimera.
    Matsuno H; Yudoh K; Nakazawa F; Sawai T; Uzuki M; Nishioka K; Yonehara S; Nakayama J; Ohtsuki M; Kimura T
    J Rheumatol; 2002 Aug; 29(8):1609-14. PubMed ID: 12180717
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework.
    Hanf KJ; Arndt JW; Chen LL; Jarpe M; Boriack-Sjodin PA; Li Y; van Vlijmen HW; Pepinsky RB; Simon KJ; Lugovskoy A
    Methods; 2014 Jan; 65(1):68-76. PubMed ID: 23816785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
    Li Y; Li H; Smith-Gill SJ; Mariuzza RA
    Biochemistry; 2000 May; 39(21):6296-309. PubMed ID: 10828942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human-engineered monoclonal antibodies retain full specific binding activity by preserving non-CDR complementarity-modulating residues.
    Studnicka GM; Soares S; Better M; Williams RE; Nadell R; Horwitz AH
    Protein Eng; 1994 Jun; 7(6):805-14. PubMed ID: 7937712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H; Nie Y; Huse WD; Watkins JD
    J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and humanization of a rat monoclonal Fab to human interleukin-5.
    Cook WJ; Walter LJ; Murgolo NJ; Chou CC; Petro M; Zavodny PJ; Narula SK; Ramanathan L; Trotta PP; Nagabhushan TL
    Protein Eng; 1996 Jul; 9(7):623-8. PubMed ID: 8844835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing.
    Roguska MA; Pedersen JT; Henry AH; Searle SM; Roja CM; Avery B; Hoffee M; Cook S; Lambert JM; Blättler WA; Rees AR; Guild BC
    Protein Eng; 1996 Oct; 9(10):895-904. PubMed ID: 8931129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
    Chen Y; Wiesmann C; Fuh G; Li B; Christinger HW; McKay P; de Vos AM; Lowman HB
    J Mol Biol; 1999 Nov; 293(4):865-81. PubMed ID: 10543973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC; Shan L; Goldsteen BZ; Guddat LW; Thakur A; Landolfi NF; Co MS; Vasquez M; Queen C; Ramsland PA; Edmundson AB
    J Mol Recognit; 1999; 12(1):19-32. PubMed ID: 10398393
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528.
    Makabe K; Nakanishi T; Tsumoto K; Tanaka Y; Kondo H; Umetsu M; Sone Y; Asano R; Kumagai I
    J Biol Chem; 2008 Jan; 283(2):1156-66. PubMed ID: 17947238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation.
    Kettleborough CA; Saldanha J; Heath VJ; Morrison CJ; Bendig MM
    Protein Eng; 1991 Oct; 4(7):773-83. PubMed ID: 1798701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
    Mylvaganam SE; Paterson Y; Getzoff ED
    J Mol Biol; 1998 Aug; 281(2):301-22. PubMed ID: 9698550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity.
    Ichikawa K; Yoshida-Kato H; Ohtsuki M; Ohsumi J; Yamaguchi J; Takahashi S; Tani Y; Watanabe M; Shiraishi A; Nishioka K; Yonehara S; Serizawa N
    Int Immunol; 2000 Apr; 12(4):555-62. PubMed ID: 10744657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of IgE-dependent histamine release from human peripheral blood basophils by humanized Fab fragments that recognize the membrane proximal domain of the human Fc epsilon RI alpha-chain.
    Takai T; Yuuki T; Ra C
    Int Arch Allergy Immunol; 2000 Dec; 123(4):308-18. PubMed ID: 11146388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies.
    Poulas K; Eliopoulos E; Vatzaki E; Navaza J; Kontou M; Oikonomakos N; Acharya KR; Tzartos SJ
    Eur J Biochem; 2001 Jul; 268(13):3685-93. PubMed ID: 11432734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.