BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

610 related articles for article (PubMed ID: 12499918)

  • 21. HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis.
    Fang J; Yan L; Shing Y; Moses MA
    Cancer Res; 2001 Aug; 61(15):5731-5. PubMed ID: 11479208
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells.
    El Awad B; Kreft B; Wolber EM; Hellwig-Bürgel T; Metzen E; Fandrey J; Jelkmann W
    Kidney Int; 2000 Jul; 58(1):43-50. PubMed ID: 10886548
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors.
    Tsuzuki Y; Fukumura D; Oosthuyse B; Koike C; Carmeliet P; Jain RK
    Cancer Res; 2000 Nov; 60(22):6248-52. PubMed ID: 11103778
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines.
    Blancher C; Moore JW; Talks KL; Houlbrook S; Harris AL
    Cancer Res; 2000 Dec; 60(24):7106-13. PubMed ID: 11156418
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bcl-2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF-1-mediated transcriptional activity.
    Iervolino A; Trisciuoglio D; Ribatti D; Candiloro A; Biroccio A; Zupi G; Del Bufalo D
    FASEB J; 2002 Sep; 16(11):1453-5. PubMed ID: 12205045
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.
    Görlach A; Diebold I; Schini-Kerth VB; Berchner-Pfannschmidt U; Roth U; Brandes RP; Kietzmann T; Busse R
    Circ Res; 2001 Jul; 89(1):47-54. PubMed ID: 11440977
    [TBL] [Abstract][Full Text] [Related]  

  • 27. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
    Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
    Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line.
    Liu XH; Kirschenbaum A; Lu M; Yao S; Dosoretz A; Holland JF; Levine AC
    J Biol Chem; 2002 Dec; 277(51):50081-6. PubMed ID: 12401798
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.
    Fukuda R; Kelly B; Semenza GL
    Cancer Res; 2003 May; 63(9):2330-4. PubMed ID: 12727858
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1.
    Liu LX; Lu H; Luo Y; Date T; Belanger AJ; Vincent KA; Akita GY; Goldberg M; Cheng SH; Gregory RJ; Jiang C
    Biochem Biophys Res Commun; 2002 Mar; 291(4):908-14. PubMed ID: 11866451
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.
    Hui EP; Chan AT; Pezzella F; Turley H; To KF; Poon TC; Zee B; Mo F; Teo PM; Huang DP; Gatter KC; Johnson PJ; Harris AL
    Clin Cancer Res; 2002 Aug; 8(8):2595-604. PubMed ID: 12171890
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A mycobacterial iron chelator, desferri-exochelin, induces hypoxia-inducible factors 1 and 2, NIP3, and vascular endothelial growth factor in cancer cell lines.
    Chong TW; Horwitz LD; Moore JW; Sowter HM; Harris AL
    Cancer Res; 2002 Dec; 62(23):6924-7. PubMed ID: 12460908
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death.
    Kotch LE; Iyer NV; Laughner E; Semenza GL
    Dev Biol; 1999 May; 209(2):254-67. PubMed ID: 10328919
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A radicicol derivative, KF58333, inhibits expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor, angiogenesis and growth of human breast cancer xenografts.
    Kurebayashi J; Otsuki T; Kurosumi M; Soga S; Akinaga S; Sonoo H
    Jpn J Cancer Res; 2001 Dec; 92(12):1342-51. PubMed ID: 11749701
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Protein kinases and the hypoxia-inducible factor-1, two switches in angiogenesis.
    Mazure NM; Brahimi-Horn MC; Pouysségur J
    Curr Pharm Des; 2003; 9(7):531-41. PubMed ID: 12570801
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression.
    Sánchez-Elsner T; Botella LM; Velasco B; Corbí A; Attisano L; Bernabéu C
    J Biol Chem; 2001 Oct; 276(42):38527-35. PubMed ID: 11486006
    [TBL] [Abstract][Full Text] [Related]  

  • 38. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.
    Mayerhofer M; Valent P; Sperr WR; Griffin JD; Sillaber C
    Blood; 2002 Nov; 100(10):3767-75. PubMed ID: 12393646
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Role of AP-1 and HIF-1 transcription factors in TGF-beta activation of VEGF expression.
    Shih SC; Claffey KP
    Growth Factors; 2001; 19(1):19-34. PubMed ID: 11678207
    [TBL] [Abstract][Full Text] [Related]  

  • 40. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
    Gray MJ; Zhang J; Ellis LM; Semenza GL; Evans DB; Watowich SS; Gallick GE
    Oncogene; 2005 Apr; 24(19):3110-20. PubMed ID: 15735682
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 31.