422 related articles for article (PubMed ID: 12502352)
21. Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.
Tang H; Ning FX; Wei YB; Huang SL; Huang ZS; Chan AS; Gu LQ
Bioorg Med Chem Lett; 2007 Jul; 17(13):3765-8. PubMed ID: 17451950
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.
Huang L; Luo Z; He F; Lu J; Li X
Bioorg Med Chem; 2010 Jun; 18(12):4475-84. PubMed ID: 20471843
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.
Camps P; Formosa X; Muñoz-Torrero D; Petrignet J; Badia A; Clos MV
J Med Chem; 2005 Mar; 48(6):1701-4. PubMed ID: 15771413
[TBL] [Abstract][Full Text] [Related]
24. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.
Huang L; Shi A; He F; Li X
Bioorg Med Chem; 2010 Feb; 18(3):1244-51. PubMed ID: 20056426
[TBL] [Abstract][Full Text] [Related]
25. Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.
Bolognesi ML; Bartolini M; Cavalli A; Andrisano V; Rosini M; Minarini A; Melchiorre C
J Med Chem; 2004 Nov; 47(24):5945-52. PubMed ID: 15537349
[TBL] [Abstract][Full Text] [Related]
26. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Fang L; Kraus B; Lehmann J; Heilmann J; Zhang Y; Decker M
Bioorg Med Chem Lett; 2008 May; 18(9):2905-9. PubMed ID: 18406135
[TBL] [Abstract][Full Text] [Related]
27. Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease.
Bolognesi ML; Cavalli A; Valgimigli L; Bartolini M; Rosini M; Andrisano V; Recanatini M; Melchiorre C
J Med Chem; 2007 Dec; 50(26):6446-9. PubMed ID: 18047264
[TBL] [Abstract][Full Text] [Related]
28. Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge.
Rydberg EH; Brumshtein B; Greenblatt HM; Wong DM; Shaya D; Williams LD; Carlier PR; Pang YP; Silman I; Sussman JL
J Med Chem; 2006 Sep; 49(18):5491-500. PubMed ID: 16942022
[TBL] [Abstract][Full Text] [Related]
29. Bis(7)-tacrine derivatives as multitarget-directed ligands: Focus on anticholinesterase and antiamyloid activities.
Bolognesi ML; Bartolini M; Mancini F; Chiriano G; Ceccarini L; Rosini M; Milelli A; Tumiatti V; Andrisano V; Melchiorre C
ChemMedChem; 2010 Aug; 5(8):1215-20. PubMed ID: 20486153
[No Abstract] [Full Text] [Related]
30. Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands.
Loewenstein Y; Gnatt A; Neville LF; Soreq H
J Mol Biol; 1993 Nov; 234(2):289-96. PubMed ID: 8230213
[TBL] [Abstract][Full Text] [Related]
31. Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism.
Lange JH; Coolen HK; van der Neut MA; Borst AJ; Stork B; Verveer PC; Kruse CG
J Med Chem; 2010 Feb; 53(3):1338-46. PubMed ID: 20047331
[TBL] [Abstract][Full Text] [Related]
32. Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors.
Carolan CG; Dillon GP; Gaynor JM; Reidy S; Ryder SA; Khan D; Marquez JF; Gilmer JF
J Med Chem; 2008 Oct; 51(20):6400-9. PubMed ID: 18817366
[TBL] [Abstract][Full Text] [Related]
33. Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.
Decker M
J Med Chem; 2006 Sep; 49(18):5411-3. PubMed ID: 16942014
[TBL] [Abstract][Full Text] [Related]
34. Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.
Alptüzün V; Prinz M; Hörr V; Scheiber J; Radacki K; Fallarero A; Vuorela P; Engels B; Braunschweig H; Erciyas E; Holzgrabe U
Bioorg Med Chem; 2010 Mar; 18(5):2049-59. PubMed ID: 20149667
[TBL] [Abstract][Full Text] [Related]
35. Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
Korabecny J; Musilek K; Holas O; Binder J; Zemek F; Marek J; Pohanka M; Opletalova V; Dohnal V; Kuca K
Bioorg Med Chem Lett; 2010 Oct; 20(20):6093-5. PubMed ID: 20817518
[TBL] [Abstract][Full Text] [Related]
36. Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
Alonso D; Dorronsoro I; Rubio L; Muñoz P; García-Palomero E; Del Monte M; Bidon-Chanal A; Orozco M; Luque FJ; Castro A; Medina M; Martínez A
Bioorg Med Chem; 2005 Dec; 13(24):6588-97. PubMed ID: 16230018
[TBL] [Abstract][Full Text] [Related]
37. In-situ synthesis of a tacrine-triazole-based inhibitor of acetylcholinesterase: configurational selection imposed by steric interactions.
Senapati S; Cheng Y; McCammon JA
J Med Chem; 2006 Oct; 49(21):6222-30. PubMed ID: 17034128
[TBL] [Abstract][Full Text] [Related]
38. Rational approach to discover multipotent anti-Alzheimer drugs.
Rosini M; Andrisano V; Bartolini M; Bolognesi ML; Hrelia P; Minarini A; Tarozzi A; Melchiorre C
J Med Chem; 2005 Jan; 48(2):360-3. PubMed ID: 15658850
[TBL] [Abstract][Full Text] [Related]
39. Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors.
Shen Q; Peng Q; Shao J; Liu X; Huang Z; Pu X; Ma L; Li YM; Chan AS; Gu L
Eur J Med Chem; 2005 Dec; 40(12):1307-15. PubMed ID: 16182411
[TBL] [Abstract][Full Text] [Related]
40. Synthesis, biological activity, and docking studies of new acetylcholinesterase inhibitors of the bispyridinium type.
Kapková P; Stiefl N; Sürig U; Engels B; Baumann K; Holzgrabe U
Arch Pharm (Weinheim); 2003 Nov; 336(11):523-40. PubMed ID: 14639745
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]