353 related articles for article (PubMed ID: 12503076)
1. DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors.
Yin D; Xie D; Hofmann WK; Zhang W; Asotra K; Wong R; Black KL; Koeffler HP
Mol Carcinog; 2003 Jan; 36(1):23-31. PubMed ID: 12503076
[TBL] [Abstract][Full Text] [Related]
2. Hypermethylation of the DNA repair gene MGMT: association with TP53 G:C to A:T transitions in a series of 469 nervous system tumors.
Bello MJ; Alonso ME; Amiñoso C; Anselmo NP; Arjona D; Gonzalez-Gomez P; Lopez-Marin I; de Campos JM; Gutierrez M; Isla A; Kusak ME; Lassaletta L; Sarasa JL; Vaquero J; Casartelli C; Rey JA
Mutat Res; 2004 Oct; 554(1-2):23-32. PubMed ID: 15450401
[TBL] [Abstract][Full Text] [Related]
3. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
Esteller M; Risques RA; Toyota M; Capella G; Moreno V; Peinado MA; Baylin SB; Herman JG
Cancer Res; 2001 Jun; 61(12):4689-92. PubMed ID: 11406538
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma.
Zhang L; Lu W; Miao X; Xing D; Tan W; Lin D
Carcinogenesis; 2003 Jun; 24(6):1039-44. PubMed ID: 12807758
[TBL] [Abstract][Full Text] [Related]
5. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado MA; Watkins DN; Issa JP; Sidransky D; Baylin SB; Herman JG
Cancer Res; 2000 May; 60(9):2368-71. PubMed ID: 10811111
[TBL] [Abstract][Full Text] [Related]
6. O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
Wolf P; Hu YC; Doffek K; Sidransky D; Ahrendt SA
Cancer Res; 2001 Nov; 61(22):8113-7. PubMed ID: 11719438
[TBL] [Abstract][Full Text] [Related]
7. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
Esteller M; Hamilton SR; Burger PC; Baylin SB; Herman JG
Cancer Res; 1999 Feb; 59(4):793-7. PubMed ID: 10029064
[TBL] [Abstract][Full Text] [Related]
8. O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma.
Zuo C; Ai L; Ratliff P; Suen JY; Hanna E; Brent TP; Fan CY
Cancer Epidemiol Biomarkers Prev; 2004 Jun; 13(6):967-75. PubMed ID: 15184253
[TBL] [Abstract][Full Text] [Related]
9. Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer.
Esteller M; Herman JG
Oncogene; 2004 Jan; 23(1):1-8. PubMed ID: 14712205
[TBL] [Abstract][Full Text] [Related]
10. Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status.
Wu JY; Wang J; Lai JC; Cheng YW; Yeh KT; Wu TC; Chen CY; Lee H
Ann Surg Oncol; 2008 Nov; 15(11):3272-7. PubMed ID: 18712569
[TBL] [Abstract][Full Text] [Related]
11. Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations.
Kim JI; Suh JT; Choi KU; Kang HJ; Shin DH; Lee IS; Moon TY; Kim WT
Hum Pathol; 2009 Jul; 40(7):934-41. PubMed ID: 19356788
[TBL] [Abstract][Full Text] [Related]
12. A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis.
Hattermann K; Mehdorn HM; Mentlein R; Schultka S; Held-Feindt J
Anal Biochem; 2008 Jun; 377(1):62-71. PubMed ID: 18384736
[TBL] [Abstract][Full Text] [Related]
13. [Promoter hypermethylation of DNA repair gene O6-methylguanine DNA methyltransferase in laryngeal squamous cell carcinoma].
Zhang S; Kong WJ; Liu Z
Zhonghua Er Bi Yan Hou Ke Za Zhi; 2004 Mar; 39(3):152-6. PubMed ID: 15283294
[TBL] [Abstract][Full Text] [Related]
14. Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.
Hermes M; Geisler H; Osswald H; Riehle R; Kloor D
Biochem Pharmacol; 2008 Jun; 75(11):2100-11. PubMed ID: 18395186
[TBL] [Abstract][Full Text] [Related]
15. Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma.
Shamsara J; Sharif S; Afsharnezhad S; Lotfi M; Raziee HR; Ghaffarzadegan K; Moradi A; Rahighi S; Behravan J
Cancer Invest; 2009 Oct; 27(8):825-9. PubMed ID: 19544111
[TBL] [Abstract][Full Text] [Related]
16. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
Lai JC; Cheng YW; Goan YG; Chang JT; Wu TC; Chen CY; Lee H
DNA Repair (Amst); 2008 Aug; 7(8):1352-63. PubMed ID: 18555750
[TBL] [Abstract][Full Text] [Related]
17. Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas.
Brell M; Tortosa A; Verger E; Gil JM; Viñolas N; Villá S; Acebes JJ; Caral L; Pujol T; Ferrer I; Ribalta T; Graus F
Clin Cancer Res; 2005 Jul; 11(14):5167-74. PubMed ID: 16033832
[TBL] [Abstract][Full Text] [Related]
18. MGMT hypermethylation: a prognostic foe, a predictive friend.
Jacinto FV; Esteller M
DNA Repair (Amst); 2007 Aug; 6(8):1155-60. PubMed ID: 17482895
[TBL] [Abstract][Full Text] [Related]
19. Promoter methylation and polymorphisms of the MGMT gene in glioblastomas: a population-based study.
Zawlik I; Vaccarella S; Kita D; Mittelbronn M; Franceschi S; Ohgaki H
Neuroepidemiology; 2009; 32(1):21-9. PubMed ID: 18997474
[TBL] [Abstract][Full Text] [Related]
20. CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
Bhakat KK; Mitra S
Carcinogenesis; 2003 Aug; 24(8):1337-45. PubMed ID: 12807730
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]