121 related articles for article (PubMed ID: 12503185)
1. Roles of DNA repair methyltransferase in mutagenesis and carcinogenesis.
Sekiguchi M; Sakumi K
Jpn J Hum Genet; 1997 Sep; 42(3):389-99. PubMed ID: 12503185
[TBL] [Abstract][Full Text] [Related]
2. [Role of O6-methylguanine-DNA methyltransferase in repair of DNA damaged by alkylating agents].
Sekiguchi M; Hayakawa H; Kodama K; Ishizaki K; Ikenaga M
Gan To Kagaku Ryoho; 1989 Mar; 16(3 Pt 2):466-72. PubMed ID: 2495773
[TBL] [Abstract][Full Text] [Related]
3. DNA-repair methyltransferase as a molecular device for preventing mutation and cancer.
Sekiguchi M; Nakabeppu Y; Sakumi K; Tuzuki T
J Cancer Res Clin Oncol; 1996; 122(4):199-206. PubMed ID: 8601571
[TBL] [Abstract][Full Text] [Related]
4. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
Dosch J; Kaina B
Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
[TBL] [Abstract][Full Text] [Related]
5. Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent.
Tsuzuki T; Sakumi K; Shiraishi A; Kawate H; Igarashi H; Iwakuma T; Tominaga Y; Zhang S; Shimizu S; Ishikawa T et AL
Carcinogenesis; 1996 Jun; 17(6):1215-20. PubMed ID: 8681434
[TBL] [Abstract][Full Text] [Related]
6. Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
Allay E; Veigl M; Gerson SL
Oncogene; 1999 Jun; 18(25):3783-7. PubMed ID: 10391687
[TBL] [Abstract][Full Text] [Related]
7. Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis.
Becker K; Dosch J; Gregel CM; Martin BA; Kaina B
Cancer Res; 1996 Jul; 56(14):3244-9. PubMed ID: 8764116
[TBL] [Abstract][Full Text] [Related]
8. Transgenic cancer resistant mice carrying the E. coli O6-alkylguanine-DNA alkyltransferase gene, ada.
Rajewsky MF
Jpn J Cancer Res; 1993 Apr; 84(4):inside front cover. PubMed ID: 8514602
[No Abstract] [Full Text] [Related]
9. Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
Dumenco LL; Arce C; Norton K; Yun J; Wagner T; Gerson SL
Cancer Res; 1991 Jul; 51(13):3391-8. PubMed ID: 2054779
[TBL] [Abstract][Full Text] [Related]
10. The DNA repair protein O6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea.
Becker K; Gregel CM; Kaina B
Cancer Res; 1997 Aug; 57(16):3335-8. PubMed ID: 9269990
[TBL] [Abstract][Full Text] [Related]
11. Analysis of N-methyl-N-nitrosourea-induced mutations in a shuttle vector plasmid propagated in mouse O6-methylguanine-DNA methyltransferase-deficient cells in comparison with proficient cells.
Moriwaki S; Yagi T; Nishigori C; Imamura S; Takebe H
Cancer Res; 1991 Dec; 51(23 Pt 1):6219-23. PubMed ID: 1834328
[TBL] [Abstract][Full Text] [Related]
12. Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice.
Sakumi K; Shiraishi A; Shimizu S; Tsuzuki T; Ishikawa T; Sekiguchi M
Cancer Res; 1997 Jun; 57(12):2415-8. PubMed ID: 9192819
[TBL] [Abstract][Full Text] [Related]
13. Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.
Liu L; Allay E; Dumenco LL; Gerson SL
Cancer Res; 1994 Sep; 54(17):4648-52. PubMed ID: 8062258
[TBL] [Abstract][Full Text] [Related]
14. Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes.
Kawate H; Sakumi K; Tsuzuki T; Nakatsuru Y; Ishikawa T; Takahashi S; Takano H; Noda T; Sekiguchi M
Proc Natl Acad Sci U S A; 1998 Apr; 95(9):5116-20. PubMed ID: 9560238
[TBL] [Abstract][Full Text] [Related]
15. Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.
Hazra TK; Roy R; Biswas T; Grabowski DT; Pegg AE; Mitra S
Biochemistry; 1997 May; 36(19):5769-76. PubMed ID: 9153417
[TBL] [Abstract][Full Text] [Related]
16. Nitrosamine-induced cancer: selective repair and conformational differences between O6-methylguanine residues in different positions in and around codon 12 of rat H-ras.
Georgiadis P; Smith CA; Swann PF
Cancer Res; 1991 Nov; 51(21):5843-50. PubMed ID: 1933853
[TBL] [Abstract][Full Text] [Related]
17. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
18. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
[TBL] [Abstract][Full Text] [Related]
19. Alkylation carcinogenesis in mice with altered levels of DNA repair methyltransferase.
Sekiguchi M; Sanada M
Prog Exp Tumor Res; 1999; 35():25-36. PubMed ID: 10377749
[No Abstract] [Full Text] [Related]
20. Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine.
Bentivegna SS; Bresnick E
Cancer Res; 1994 Jan; 54(2):327-9. PubMed ID: 8275462
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
