BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 12505988)

  • 1. Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis.
    Egli D; Selvaraj A; Yepiskoposyan H; Zhang B; Hafen E; Georgiev O; Schaffner W
    EMBO J; 2003 Jan; 22(1):100-8. PubMed ID: 12505988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification.
    Egli D; Domènech J; Selvaraj A; Balamurugan K; Hua H; Capdevila M; Georgiev O; Schaffner W; Atrian S
    Genes Cells; 2006 Jun; 11(6):647-58. PubMed ID: 16716195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals.
    Zhang B; Egli D; Georgiev O; Schaffner W
    Mol Cell Biol; 2001 Jul; 21(14):4505-14. PubMed ID: 11416130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.
    Egli D; Yepiskoposyan H; Selvaraj A; Balamurugan K; Rajaram R; Simons A; Multhaup G; Mettler S; Vardanyan A; Georgiev O; Schaffner W
    Mol Cell Biol; 2006 Mar; 26(6):2286-96. PubMed ID: 16508004
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissection of Drosophila MTF-1 reveals a domain for differential target gene activation upon copper overload vs. copper starvation.
    Günther V; Waldvogel D; Nosswitz M; Georgiev O; Schaffner W
    Int J Biochem Cell Biol; 2012 Feb; 44(2):404-11. PubMed ID: 22138226
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparison.
    Balamurugan K; Egli D; Selvaraj A; Zhang B; Georgiev O; Schaffner W
    Biol Chem; 2004 Jul; 385(7):597-603. PubMed ID: 15318808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc.
    Yepiskoposyan H; Egli D; Fergestad T; Selvaraj A; Treiber C; Multhaup G; Georgiev O; Schaffner W
    Nucleic Acids Res; 2006; 34(17):4866-77. PubMed ID: 16973896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of MtnE, the fifth metallothionein member in Drosophila.
    Atanesyan L; Günther V; Celniker SE; Georgiev O; Schaffner W
    J Biol Inorg Chem; 2011 Oct; 16(7):1047-56. PubMed ID: 21870250
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.
    Heuchel R; Radtke F; Georgiev O; Stark G; Aguet M; Schaffner W
    EMBO J; 1994 Jun; 13(12):2870-5. PubMed ID: 8026472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver.
    Wang Y; Wimmer U; Lichtlen P; Inderbitzin D; Stieger B; Meier PJ; Hunziker L; Stallmach T; Forrer R; Rülicke T; Georgiev O; Schaffner W
    FASEB J; 2004 Jul; 18(10):1071-9. PubMed ID: 15226267
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein.
    Zhang B; Georgiev O; Hagmann M; Günes C; Cramer M; Faller P; Vasák M; Schaffner W
    Mol Cell Biol; 2003 Dec; 23(23):8471-85. PubMed ID: 14612393
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1).
    Saini N; Georgiev O; Schaffner W
    Mol Cell Biol; 2011 May; 31(10):2151-61. PubMed ID: 21383066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of metallothionein gene expression by oxidative stress and metal ions.
    Andrews GK
    Biochem Pharmacol; 2000 Jan; 59(1):95-104. PubMed ID: 10605938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The taste of heavy metals: gene regulation by MTF-1.
    Günther V; Lindert U; Schaffner W
    Biochim Biophys Acta; 2012 Sep; 1823(9):1416-25. PubMed ID: 22289350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Target gene search for the metal-responsive transcription factor MTF-1.
    Lichtlen P; Wang Y; Belser T; Georgiev O; Certa U; Sack R; Schaffner W
    Nucleic Acids Res; 2001 Apr; 29(7):1514-23. PubMed ID: 11266553
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.
    Lichtlen P; Schaffner W
    Bioessays; 2001 Nov; 23(11):1010-7. PubMed ID: 11746217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter.
    Jiang H; Daniels PJ; Andrews GK
    J Biol Chem; 2003 Aug; 278(32):30394-402. PubMed ID: 12764133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activation.
    Sims HI; Chirn GW; Marr MT
    Proc Natl Acad Sci U S A; 2012 Oct; 109(41):16516-21. PubMed ID: 23012419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel cysteine cluster in human metal-responsive transcription factor 1 is required for heavy metal-induced transcriptional activation in vivo.
    Chen X; Zhang B; Harmon PM; Schaffner W; Peterson DO; Giedroc DP
    J Biol Chem; 2004 Feb; 279(6):4515-22. PubMed ID: 14610091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene.
    Langmade SJ; Ravindra R; Daniels PJ; Andrews GK
    J Biol Chem; 2000 Nov; 275(44):34803-9. PubMed ID: 10952993
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.