307 related articles for article (PubMed ID: 12506132)
1. Metabolism of Cisplatin to a nephrotoxin in proximal tubule cells.
Townsend DM; Deng M; Zhang L; Lapus MG; Hanigan MH
J Am Soc Nephrol; 2003 Jan; 14(1):1-10. PubMed ID: 12506132
[TBL] [Abstract][Full Text] [Related]
2. Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin.
Zhang L; Hanigan MH
J Pharmacol Exp Ther; 2003 Sep; 306(3):988-94. PubMed ID: 12750429
[TBL] [Abstract][Full Text] [Related]
3. High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of Cisplatin.
Townsend DM; Marto JA; Deng M; Macdonald TJ; Hanigan MH
Drug Metab Dispos; 2003 Jun; 31(6):705-13. PubMed ID: 12756201
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice.
Townsend DM; Hanigan MH
J Pharmacol Exp Ther; 2002 Jan; 300(1):142-8. PubMed ID: 11752109
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity.
Hanigan MH; Gallagher BC; Taylor PT; Large MK
Cancer Res; 1994 Nov; 54(22):5925-9. PubMed ID: 7954424
[TBL] [Abstract][Full Text] [Related]
6. Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells.
Zhang L; Cooper AJ; Krasnikov BF; Xu H; Bubber P; Pinto JT; Gibson GE; Hanigan MH
Biochemistry; 2006 Jul; 45(29):8959-71. PubMed ID: 16846239
[TBL] [Abstract][Full Text] [Related]
7. The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.
Stevens J; Hayden P; Taylor G
J Biol Chem; 1986 Mar; 261(7):3325-32. PubMed ID: 3753976
[TBL] [Abstract][Full Text] [Related]
8. gamma-Glutamyl transpeptidase catalyses the extracellular detoxification of cisplatin in a human cell line derived from the proximal convoluted tubule of the kidney.
Paolicchi A; Sotiropuolou M; Perego P; Daubeuf S; Visvikis A; Lorenzini E; Franzini M; Romiti N; Chieli E; Leone R; Apostoli P; Colangelo D; Zunino F; Pompella A
Eur J Cancer; 2003 May; 39(7):996-1003. PubMed ID: 12706370
[TBL] [Abstract][Full Text] [Related]
9. Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines.
Rooseboom M; Schaaf G; Commandeur JN; Vermeulen NP; Fink-Gremmels J
J Pharmacol Exp Ther; 2002 Jun; 301(3):884-92. PubMed ID: 12023515
[TBL] [Abstract][Full Text] [Related]
10. Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity.
Townsend DM; Tew KD; He L; King JB; Hanigan MH
Biomed Pharmacother; 2009 Feb; 63(2):79-85. PubMed ID: 18819770
[TBL] [Abstract][Full Text] [Related]
11. Controversial role of gamma-glutamyl transferase activity in cisplatin nephrotoxicity.
Fliedl L; Wieser M; Manhart G; Gerstl MP; Khan A; Grillari J; Grillari-Voglauer R
ALTEX; 2014; 31(3):269-78. PubMed ID: 24664430
[TBL] [Abstract][Full Text] [Related]
12. Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats.
Kharasch ED; Hoffman GM; Thorning D; Hankins DC; Kilty CG
Anesthesiology; 1998 Jun; 88(6):1624-33. PubMed ID: 9637657
[TBL] [Abstract][Full Text] [Related]
13. Cisplatin nephrotoxicity is mediated by gamma glutamyltranspeptidase, not via a C-S lyase governed biotransformation pathway.
Wainford RD; Weaver RJ; Stewart KN; Brown P; Hawksworth GM
Toxicology; 2008 Jul; 249(2-3):184-93. PubMed ID: 18583013
[TBL] [Abstract][Full Text] [Related]
14. Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase.
Hausheer FH; Shanmugarajah D; Leverett BD; Chen X; Huang Q; Kochat H; Petluru PN; Parker AR
Cancer Chemother Pharmacol; 2010 Apr; 65(5):941-51. PubMed ID: 19714332
[TBL] [Abstract][Full Text] [Related]
15. Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
Chen JC; Stevens JL; Trifillis AL; Jones TW
Toxicol Appl Pharmacol; 1990 May; 103(3):463-73. PubMed ID: 2339419
[TBL] [Abstract][Full Text] [Related]
16. Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo.
Hanigan MH; Gallagher BC; Townsend DM; Gabarra V
Carcinogenesis; 1999 Apr; 20(4):553-9. PubMed ID: 10223181
[TBL] [Abstract][Full Text] [Related]
17. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
McGoldrick TA; Lock EA; Rodilla V; Hawksworth GM
Arch Toxicol; 2003 Jul; 77(7):365-70. PubMed ID: 12700887
[TBL] [Abstract][Full Text] [Related]
18. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
[TBL] [Abstract][Full Text] [Related]
19. Fibrate prevents cisplatin-induced proximal tubule cell death.
Nagothu KK; Bhatt R; Kaushal GP; Portilla D
Kidney Int; 2005 Dec; 68(6):2680-93. PubMed ID: 16316343
[TBL] [Abstract][Full Text] [Related]
20. In vivo nephrotoxic action of an isomeric mixture of S-(1-phenyl-2-hydroxyethyl)glutathione and S-(2-phenyl-2-hydroxyethyl)glutathione in Fischer-344 rats.
Chakrabarti S; Malick MA
Toxicology; 1991 Mar; 67(1):15-27. PubMed ID: 1673268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
