BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 12512385)

  • 1. Clinical development of mammalian target of rapamycin inhibitors.
    Dancey JE
    Hematol Oncol Clin North Am; 2002 Oct; 16(5):1101-14. PubMed ID: 12512385
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Therapeutic potential of target of rapamycin inhibitors.
    Easton JB; Houghton PJ
    Expert Opin Ther Targets; 2004 Dec; 8(6):551-64. PubMed ID: 15584862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin's resurrection: a new way to target the cancer cell cycle.
    Garber K
    J Natl Cancer Inst; 2001 Oct; 93(20):1517-9. PubMed ID: 11604470
    [No Abstract]   [Full Text] [Related]  

  • 4. Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway.
    Smolewski P
    Anticancer Drugs; 2006 Jun; 17(5):487-94. PubMed ID: 16702804
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.
    Hidalgo M; Rowinsky EK
    Oncogene; 2000 Dec; 19(56):6680-6. PubMed ID: 11426655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR pathway inhibitors in cancer therapy: moving past rapamycin.
    Wacheck V
    Pharmacogenomics; 2010 Sep; 11(9):1189-91. PubMed ID: 20860456
    [No Abstract]   [Full Text] [Related]  

  • 7. Current development of mTOR inhibitors as anticancer agents.
    Faivre S; Kroemer G; Raymond E
    Nat Rev Drug Discov; 2006 Aug; 5(8):671-88. PubMed ID: 16883305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
    Mourani PM; Garl PJ; Wenzlau JM; Carpenter TC; Stenmark KR; Weiser-Evans MC
    Circulation; 2004 Mar; 109(10):1299-306. PubMed ID: 14993145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T; Nishioka C; Bandobashi K; Yang Y; Kuwayama Y; Adachi Y; Takeuchi T; Koeffler HP; Taguchi H
    Leuk Res; 2007 May; 31(5):673-82. PubMed ID: 17007924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of PI3K inhibitors: lessons learned from early clinical trials.
    Rodon J; Dienstmann R; Serra V; Tabernero J
    Nat Rev Clin Oncol; 2013 Mar; 10(3):143-53. PubMed ID: 23400000
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo.
    Ren H; Chen M; Yue P; Tao H; Owonikoko TK; Ramalingam SS; Khuri FR; Sun SY
    Cancer Lett; 2012 Dec; 325(2):139-46. PubMed ID: 22781393
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Current status and challenges associated with targeting mTOR for cancer therapy.
    Dowling RJ; Pollak M; Sonenberg N
    BioDrugs; 2009; 23(2):77-91. PubMed ID: 19489650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT; Heydrick SJ; Fox HL; Kimball SR; Jefferson LS; Lynch CJ
    J Cell Biochem; 2000 Sep; 79(3):427-41. PubMed ID: 10972980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mammalian target of rapamycin inhibition induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab.
    Wanner K; Hipp S; Oelsner M; Ringshausen I; Bogner C; Peschel C; Decker T
    Br J Haematol; 2006 Sep; 134(5):475-84. PubMed ID: 16856892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin.
    Meric-Bernstam F; Mills GB
    Semin Oncol; 2004 Dec; 31(6 Suppl 16):10-7; discussion 33. PubMed ID: 15799239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.
    Yu J; Henske EP
    Cancer Res; 2006 Oct; 66(19):9461-6. PubMed ID: 17018601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.
    Huang S; Houghton PJ
    Curr Opin Investig Drugs; 2002 Feb; 3(2):295-304. PubMed ID: 12020063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling.
    Ikezoe T; Nishioka C; Tasaka T; Yang Y; Komatsu N; Togitani K; Koeffler HP; Taguchi H
    Mol Cancer Ther; 2006 Oct; 5(10):2522-30. PubMed ID: 17041096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of translation initiation by FRAP/mTOR.
    Gingras AC; Raught B; Sonenberg N
    Genes Dev; 2001 Apr; 15(7):807-26. PubMed ID: 11297505
    [No Abstract]   [Full Text] [Related]  

  • 20. Therapeutic targets: MTOR and related pathways.
    Dancey JE
    Cancer Biol Ther; 2006 Sep; 5(9):1065-73. PubMed ID: 16969122
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.