These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

442 related articles for article (PubMed ID: 12514700)

  • 1. Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.
    Yang LB; Lindholm K; Yan R; Citron M; Xia W; Yang XL; Beach T; Sue L; Wong P; Price D; Li R; Shen Y
    Nat Med; 2003 Jan; 9(1):3-4. PubMed ID: 12514700
    [No Abstract]   [Full Text] [Related]  

  • 2. The molecular link between beta- and gamma-secretase activity on the amyloid beta precursor protein.
    Tabaton M; Tamagno E
    Cell Mol Life Sci; 2007 Sep; 64(17):2211-8. PubMed ID: 17604999
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice.
    Zohar O; Pick CG; Cavallaro S; Chapman J; Katzav A; Milman A; Alkon DL
    Neurobiol Aging; 2005; 26(8):1167-75. PubMed ID: 15917100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.
    Zhong Z; Ewers M; Teipel S; Bürger K; Wallin A; Blennow K; He P; McAllister C; Hampel H; Shen Y
    Arch Gen Psychiatry; 2007 Jun; 64(6):718-26. PubMed ID: 17548753
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH; O'Neill C
    Biochem Soc Trans; 2007 Jun; 35(Pt 3):574-6. PubMed ID: 17511655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tracking Alzheimer's.
    Roberts L
    US News World Rep; 1999 Nov; 127(17):73. PubMed ID: 10623301
    [No Abstract]   [Full Text] [Related]  

  • 9. Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain.
    Stockley JH; Ravid R; O'Neill C
    FEBS Lett; 2006 Dec; 580(28-29):6550-60. PubMed ID: 17113083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
    Nawrot B
    Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
    Hook VY; Reisine TD
    J Neurosci Res; 2003 Nov; 74(3):393-405. PubMed ID: 14598316
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
    Holsinger RM; McLean CA; Collins SJ; Masters CL; Evin G
    Ann Neurol; 2004 Jun; 55(6):898-9. PubMed ID: 15174031
    [No Abstract]   [Full Text] [Related]  

  • 13. Four companies announce discovery of beta-secretase gene.
    Phimister B
    Nat Biotechnol; 2000 Jan; 18(1):16. PubMed ID: 10625376
    [No Abstract]   [Full Text] [Related]  

  • 14. Aspartic proteases involved in Alzheimer's disease.
    Schmidt B
    Chembiochem; 2003 May; 4(5):366-78. PubMed ID: 12740808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
    Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H; Tabira T
    Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Decrease in age-adjusted cerebrospinal fluid beta-secretase activity in Alzheimer's subjects.
    Wu G; Sankaranarayanan S; Tugusheva K; Kahana J; Seabrook G; Shi XP; King E; Devanarayan V; Cook JJ; Simon AJ
    Clin Biochem; 2008 Aug; 41(12):986-96. PubMed ID: 18489907
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
    Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
    Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.
    Pollack SJ; Lewis H
    Curr Opin Investig Drugs; 2005 Jan; 6(1):35-47. PubMed ID: 15675602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.