BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 12515506)

  • 1. DNA interchain cross-links formed by acrolein and crotonaldehyde.
    Kozekov ID; Nechev LV; Moseley MS; Harris CM; Rizzo CJ; Stone MP; Harris TM
    J Am Chem Soc; 2003 Jan; 125(1):50-61. PubMed ID: 12515506
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.
    Cho YJ; Kim HY; Huang H; Slutsky A; Minko IG; Wang H; Nechev LV; Kozekov ID; Kozekova A; Tamura P; Jacob J; Voehler M; Harris TM; Lloyd RS; Rizzo CJ; Stone MP
    J Am Chem Soc; 2005 Dec; 127(50):17686-96. PubMed ID: 16351098
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interchain cross-linking of DNA mediated by the principal adduct of acrolein.
    Kozekov ID; Nechev LV; Sanchez A; Harris CM; Lloyd RS; Harris TM
    Chem Res Toxicol; 2001 Nov; 14(11):1482-5. PubMed ID: 11712904
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence.
    Cho YJ; Wang H; Kozekov ID; Kurtz AJ; Jacob J; Voehler M; Smith J; Harris TM; Lloyd RS; Rizzo CJ; Stone MP
    Chem Res Toxicol; 2006 Feb; 19(2):195-208. PubMed ID: 16485895
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.
    Huang H; Kim HY; Kozekov ID; Cho YJ; Wang H; Kozekova A; Harris TM; Rizzo CJ; Stone MP
    J Am Chem Soc; 2009 Jun; 131(24):8416-24. PubMed ID: 19530727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence.
    Cho YJ; Wang H; Kozekov ID; Kozekova A; Kurtz AJ; Jacob J; Voehler M; Smith J; Harris TM; Rizzo CJ; Lloyd RS; Stone MP
    Chem Res Toxicol; 2006 Aug; 19(8):1019-29. PubMed ID: 16918240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde.
    Chung FL; Young R; Hecht SS
    Cancer Res; 1984 Mar; 44(3):990-5. PubMed ID: 6318992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.
    Minko IG; Kozekov ID; Harris TM; Rizzo CJ; Lloyd RS; Stone MP
    Chem Res Toxicol; 2009 May; 22(5):759-78. PubMed ID: 19397281
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA.
    Huang H; Wang H; Qi N; Kozekova A; Rizzo CJ; Stone MP
    J Am Chem Soc; 2008 Aug; 130(33):10898-906. PubMed ID: 18661996
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links.
    Cheng G; Shi Y; Sturla SJ; Jalas JR; McIntee EJ; Villalta PW; Wang M; Hecht SS
    Chem Res Toxicol; 2003 Feb; 16(2):145-52. PubMed ID: 12588185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,N2-deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage.
    Kurtz AJ; Lloyd RS
    J Biol Chem; 2003 Feb; 278(8):5970-6. PubMed ID: 12502710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Detection of an interchain carbinolamine cross-link formed in a CpG sequence by the acrolein DNA adduct gamma-OH-1,N( 2)-propano-2'-deoxyguanosine.
    Kim HY; Voehler M; Harris TM; Stone MP
    J Am Chem Soc; 2002 Aug; 124(32):9324-5. PubMed ID: 12166998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
    Huang H; Wang H; Qi N; Lloyd RS; Rizzo CJ; Stone MP
    Biochemistry; 2008 Nov; 47(44):11457-72. PubMed ID: 18847226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts.
    Sanchez AM; Minko IG; Kurtz AJ; Kanuri M; Moriya M; Lloyd RS
    Chem Res Toxicol; 2003 Aug; 16(8):1019-28. PubMed ID: 12924930
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.
    Stone MP; Cho YJ; Huang H; Kim HY; Kozekov ID; Kozekova A; Wang H; Minko IG; Lloyd RS; Harris TM; Rizzo CJ
    Acc Chem Res; 2008 Jul; 41(7):793-804. PubMed ID: 18500830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct.
    Huang H; Wang H; Kozekova A; Rizzo CJ; Stone MP
    J Am Chem Soc; 2011 Oct; 133(40):16101-10. PubMed ID: 21916419
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine.
    Nechev LV; Kozekov ID; Brock AK; Rizzo CJ; Harris TM
    Chem Res Toxicol; 2002 May; 15(5):607-13. PubMed ID: 12018980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexenal and trans-4-hydroxy-2-nonenal in vitro.
    Winter CK; Segall HJ; Haddon WF
    Cancer Res; 1986 Nov; 46(11):5682-6. PubMed ID: 3756915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of DNA adducts of acetaldehyde.
    Wang M; McIntee EJ; Cheng G; Shi Y; Villalta PW; Hecht SS
    Chem Res Toxicol; 2000 Nov; 13(11):1149-57. PubMed ID: 11087437
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.
    Kozekov ID; Turesky RJ; Alas GR; Harris CM; Harris TM; Rizzo CJ
    Chem Res Toxicol; 2010 Nov; 23(11):1701-13. PubMed ID: 20964440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.