BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 12515830)

  • 1. Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators.
    Sato M; Markiewicz M; Yamanaka M; Bielawska A; Mao C; Obeid LM; Hannun YA; Trojanowska M
    J Biol Chem; 2003 Mar; 278(11):9276-82. PubMed ID: 12515830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
    Yamanaka M; Shegogue D; Pei H; Bu S; Bielawska A; Bielawski J; Pettus B; Hannun YA; Obeid L; Trojanowska M
    J Biol Chem; 2004 Dec; 279(52):53994-4001. PubMed ID: 15485866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
    Poncelet AC; de Caestecker MP; Schnaper HW
    Kidney Int; 1999 Oct; 56(4):1354-65. PubMed ID: 10504488
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells.
    Poncelet AC; Schnaper HW
    J Biol Chem; 2001 Mar; 276(10):6983-92. PubMed ID: 11114293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling.
    Qiao B; Padilla SR; Benya PD
    J Biol Chem; 2005 Apr; 280(17):17562-71. PubMed ID: 15743758
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The tumor suppressor p53 abrogates Smad-dependent collagen gene induction in mesenchymal cells.
    Ghosh AK; Bhattacharyya S; Varga J
    J Biol Chem; 2004 Nov; 279(46):47455-63. PubMed ID: 15345715
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1.
    Runyan CE; Schnaper HW; Poncelet AC
    J Biol Chem; 2004 Jan; 279(4):2632-9. PubMed ID: 14610066
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3.
    Higashi K; Inagaki Y; Fujimori K; Nakao A; Kaneko H; Nakatsuka I
    J Biol Chem; 2003 Oct; 278(44):43470-9. PubMed ID: 12917425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.
    Ghosh AK; Yuan W; Mori Y; Varga J
    Oncogene; 2000 Jul; 19(31):3546-55. PubMed ID: 10918613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidylinositol 3-kinase is involved in alpha2(I) collagen gene expression in normal and scleroderma fibroblasts.
    Asano Y; Ihn H; Yamane K; Jinnin M; Mimura Y; Tamaki K
    J Immunol; 2004 Jun; 172(11):7123-35. PubMed ID: 15153536
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of smad3 with a proximal smad-binding element of the human alpha2(I) procollagen gene promoter required for transcriptional activation by TGF-beta.
    Chen SJ; Yuan W; Lo S; Trojanowska M; Varga J
    J Cell Physiol; 2000 Jun; 183(3):381-92. PubMed ID: 10797313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3.
    Yuan W; Varga J
    J Biol Chem; 2001 Oct; 276(42):38502-10. PubMed ID: 11502752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner.
    Browne JA; Liu X; Schnaper HW; Hayashida T
    Exp Cell Res; 2013 Nov; 319(19):2928-37. PubMed ID: 24080014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription.
    Zhang W; Ou J; Inagaki Y; Greenwel P; Ramirez F
    J Biol Chem; 2000 Dec; 275(50):39237-45. PubMed ID: 11007770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-beta: involvement of Smad 3.
    Chen SJ; Yuan W; Mori Y; Levenson A; Trojanowska M; Varga J
    J Invest Dermatol; 1999 Jan; 112(1):49-57. PubMed ID: 9886263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways.
    Lei S; Dubeykovskiy A; Chakladar A; Wojtukiewicz L; Wang TC
    J Biol Chem; 2004 Oct; 279(41):42492-502. PubMed ID: 15292219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression.
    Chen SJ; Ning H; Ishida W; Sodin-Semrl S; Takagawa S; Mori Y; Varga J
    J Biol Chem; 2006 Jul; 281(30):21183-21197. PubMed ID: 16702209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factor-beta repression of the sodium/iodide symporter gene.
    Costamagna E; García B; Santisteban P
    J Biol Chem; 2004 Jan; 279(5):3439-46. PubMed ID: 14623893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Abrogation of transforming growth factor-beta signaling by SMAD7 inhibits collagen gel contraction of human dermal fibroblasts.
    Kopp J; Preis E; Said H; Hafemann B; Wickert L; Gressner AM; Pallua N; Dooley S
    J Biol Chem; 2005 Jun; 280(22):21570-6. PubMed ID: 15788410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.