637 related articles for article (PubMed ID: 12520087)
1. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
Annerén C; Welsh M
Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
[TBL] [Abstract][Full Text] [Related]
2. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
Welsh N; Makeeva N; Welsh M
Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
[TBL] [Abstract][Full Text] [Related]
3. Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK.
Annerén C; Welsh M
Mol Med; 2001 May; 7(5):301-10. PubMed ID: 11474576
[TBL] [Abstract][Full Text] [Related]
4. nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1.
Tejedo JR; Cahuana GM; Ramírez R; Esbert M; Jiménez J; Sobrino F; Bedoya FJ
Endocrinology; 2004 May; 145(5):2319-27. PubMed ID: 14764634
[TBL] [Abstract][Full Text] [Related]
5. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
Lingohr MK; Dickson LM; McCuaig JF; Hugl SR; Twardzik DR; Rhodes CJ
Diabetes; 2002 Apr; 51(4):966-76. PubMed ID: 11916914
[TBL] [Abstract][Full Text] [Related]
6. Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin.
Annerén C
J Endocrinol; 2002 Jan; 172(1):145-53. PubMed ID: 11786382
[TBL] [Abstract][Full Text] [Related]
7. Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.
Laviola L; Belsanti G; Davalli AM; Napoli R; Perrini S; Weir GC; Giorgino R; Giorgino F
Diabetes; 2001 Dec; 50(12):2709-20. PubMed ID: 11723053
[TBL] [Abstract][Full Text] [Related]
8. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
Cousin SP; Hügl SR; Myers MG; White MF; Reifel-Miller A; Rhodes CJ
Biochem J; 1999 Dec; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
[TBL] [Abstract][Full Text] [Related]
9. IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.
Telting D; van der Zon GC; Dorrestijn J; Maassen JA
Arch Physiol Biochem; 2001 Feb; 109(1):52-62. PubMed ID: 11471071
[TBL] [Abstract][Full Text] [Related]
10. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
Andreozzi F; Laratta E; Sciacqua A; Perticone F; Sesti G
Circ Res; 2004 May; 94(9):1211-8. PubMed ID: 15044323
[TBL] [Abstract][Full Text] [Related]
11. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
Mur C; Valverde AM; Kahn CR; Benito M
Diabetes; 2002 Mar; 51(3):743-54. PubMed ID: 11872675
[TBL] [Abstract][Full Text] [Related]
12. The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation.
Annerén C; Lindholm CK; Kriz V; Welsh M
Curr Mol Med; 2003 Jun; 3(4):313-24. PubMed ID: 12776987
[TBL] [Abstract][Full Text] [Related]
13. Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.
Conejo R; Lorenzo M
J Cell Physiol; 2001 Apr; 187(1):96-108. PubMed ID: 11241354
[TBL] [Abstract][Full Text] [Related]
14. Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway.
del Rincón SV; Rousseau C; Samanta R; Miller WH
Oncogene; 2003 May; 22(22):3353-60. PubMed ID: 12776186
[TBL] [Abstract][Full Text] [Related]
15. Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
Welsh M; Christmansson L; Karlsson T; Sandler S; Welsh N
Mol Med; 1999 Mar; 5(3):169-80. PubMed ID: 10404514
[TBL] [Abstract][Full Text] [Related]
16. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Andreozzi F; D'Alessandris C; Federici M; Laratta E; Del Guerra S; Del Prato S; Marchetti P; Lauro R; Perticone F; Sesti G
Endocrinology; 2004 Jun; 145(6):2845-57. PubMed ID: 15001544
[TBL] [Abstract][Full Text] [Related]
17. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.
Annerén C; Reedquist KA; Bos JL; Welsh M
J Biol Chem; 2000 Sep; 275(37):29153-61. PubMed ID: 10878015
[TBL] [Abstract][Full Text] [Related]
18. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
Bartucci M; Morelli C; Mauro L; Andò S; Surmacz E
Cancer Res; 2001 Sep; 61(18):6747-54. PubMed ID: 11559546
[TBL] [Abstract][Full Text] [Related]
19. Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.
Hennige AM; Lammers R; Arlt D; Höppner W; Strack V; Niederfellner G; Seif FJ; Häring HU; Kellerer M
Mol Cell Endocrinol; 2000 Sep; 167(1-2):69-76. PubMed ID: 11000521
[TBL] [Abstract][Full Text] [Related]
20. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
Kurihara S; Hakuno F; Takahashi S
Endocr J; 2000 Dec; 47(6):739-51. PubMed ID: 11228049
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
