BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 12521992)

  • 1. Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype.
    Oury C; Kuijpers MJ; Toth-Zsamboki E; Bonnefoy A; Danloy S; Vreys I; Feijge MA; De Vos R; Vermylen J; Heemskerk JW; Hoylaerts MF
    Blood; 2003 May; 101(10):3969-76. PubMed ID: 12521992
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen.
    Oury C; Toth-Zsamboki E; Vermylen J; Hoylaerts MF
    Blood; 2002 Oct; 100(7):2499-505. PubMed ID: 12239162
    [TBL] [Abstract][Full Text] [Related]  

  • 3. P2X1-mediated ERK2 activation amplifies the collagen-induced platelet secretion by enhancing myosin light chain kinase activation.
    Toth-Zsamboki E; Oury C; Cornelissen H; De Vos R; Vermylen J; Hoylaerts MF
    J Biol Chem; 2003 Nov; 278(47):46661-7. PubMed ID: 14500714
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen.
    Oury C; Toth-Zsamboki E; Thys C; Tytgat J; Vermylen J; Hoylaerts MF
    Thromb Haemost; 2001 Nov; 86(5):1264-71. PubMed ID: 11816716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of ADP receptors in platelet function.
    Murugappa S; Kunapuli SP
    Front Biosci; 2006 May; 11():1977-86. PubMed ID: 16368572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt].
    Hechler B; Magnenat S; Zighetti ML; Kassack MU; Ullmann H; Cazenave JP; Evans R; Cattaneo M; Gachet C
    J Pharmacol Exp Ther; 2005 Jul; 314(1):232-43. PubMed ID: 15792995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis.
    Vial C; Pitt SJ; Roberts J; Rolf MG; Mahaut-Smith MP; Evans RJ
    Blood; 2003 Nov; 102(10):3646-51. PubMed ID: 12907444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Emerging roles for P2X1 receptors in platelet activation.
    Mahaut-Smith MP; Tolhurst G; Evans RJ
    Platelets; 2004 May; 15(3):131-44. PubMed ID: 15203715
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.
    Grenegård M; Vretenbrant-Oberg K; Nylander M; Désilets S; Lindström EG; Larsson A; Ramström I; Ramström S; Lindahl TL
    J Biol Chem; 2008 Jul; 283(27):18493-504. PubMed ID: 18480058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice.
    Hechler B; Zhang Y; Eckly A; Cazenave JP; Gachet C; Ravid K
    J Thromb Haemost; 2003 Jan; 1(1):155-63. PubMed ID: 12871553
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ERK2 activation in arteriolar and venular murine thrombosis: platelet receptor GPIb vs. P2X.
    Oury C; Daenens K; Hu H; Toth-Zsamboki E; Bryckaert M; Hoylaerts MF
    J Thromb Haemost; 2006 Feb; 4(2):443-52. PubMed ID: 16420578
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets.
    Fälker K; Lange D; Presek P
    Thromb Haemost; 2004 Jul; 92(1):114-23. PubMed ID: 15213852
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors.
    Vial C; Rolf MG; Mahaut-Smith MP; Evans RJ
    Br J Pharmacol; 2002 Jan; 135(2):363-72. PubMed ID: 11815371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
    Tolhurst G; Vial C; Léon C; Gachet C; Evans RJ; Mahaut-Smith MP
    Blood; 2005 Sep; 106(5):1644-51. PubMed ID: 15914557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo.
    Hechler B; Lenain N; Marchese P; Vial C; Heim V; Freund M; Cazenave JP; Cattaneo M; Ruggeri ZM; Evans R; Gachet C
    J Exp Med; 2003 Aug; 198(4):661-7. PubMed ID: 12913094
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platelet hypersensitivity in cholesterol-fed rabbits: enhancement of thromboxane A2-dependent and thrombin-induced, thromboxane A2-independent platelet responses.
    Gross PL; Rand ML; Barrow DV; Packham MA
    Atherosclerosis; 1991 May; 88(1):77-86. PubMed ID: 1878012
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of enhanced P2X1 receptor Ca2+ influx on functional responses in human platelets.
    Rolf MG; Mahaut-Smith MP
    Thromb Haemost; 2002 Sep; 88(3):495-502. PubMed ID: 12353081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.
    Roger S; Pawlowski M; Habib A; Jandrot-Perrus M; Rosa JP; Bryckaert M
    FEBS Lett; 2004 Jan; 556(1-3):227-35. PubMed ID: 14706855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extracellular ATP inhibits agonist-induced mobilization of internal calcium in human platelets.
    Soslau G; McKenzie RJ; Brodsky I; Devlin TM
    Biochim Biophys Acta; 1995 Jul; 1268(1):73-80. PubMed ID: 7626665
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Platelet ADP receptors contribute to the initiation of intravascular coagulation.
    Leon C; Alex M; Klocke A; Morgenstern E; Moosbauer C; Eckly A; Spannagl M; Gachet C; Engelmann B
    Blood; 2004 Jan; 103(2):594-600. PubMed ID: 12969982
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.