BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

556 related articles for article (PubMed ID: 12527714)

  • 1. Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
    Venesio T; Balsamo A; Scordamaglia A; Bertolaso M; Arrigoni A; Sprujevnik T; Rossini FP; Risio M
    Mod Pathol; 2003 Jan; 16(1):57-65. PubMed ID: 12527714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H; Sutter C; Kadmon M; Otto HF; Von Knebel-Doeberitz M; Gebert J; Helmke BM
    Genes Chromosomes Cancer; 2004 Oct; 41(2):93-8. PubMed ID: 15287021
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
    Crabtree M; Sieber OM; Lipton L; Hodgson SV; Lamlum H; Thomas HJ; Neale K; Phillips RK; Heinimann K; Tomlinson IP
    Oncogene; 2003 Jul; 22(27):4257-65. PubMed ID: 12833148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.
    Hao X; Frayling IM; Willcocks TC; Han W; Tomlinson IP; Pignatelli MN; Pretlow TP; Talbot IC
    Virchows Arch; 2002 Apr; 440(4):362-6. PubMed ID: 11956815
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatic mutations in familial adenomatous polyps. Nuclear translocation of beta-catenin requires more than biallelic APC inactivation.
    Bläker H; Scholten M; Sutter C; Otto HF; Penzel R
    Am J Clin Pathol; 2003 Sep; 120(3):418-23. PubMed ID: 14502807
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients.
    Müller O; Nimmrich I; Finke U; Friedl W; Hoffmann I
    Genes Chromosomes Cancer; 1998 May; 22(1):37-41. PubMed ID: 9591632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of Wnt target genes in adenomas of familial adenomatous polyposis patients.
    D'Orazio D; Muller PY; Heinimann K; Albrecht C; Bendik I; Herzog U; Tondelli P; Bauerfeind P; Müller H; Dobbie Z
    Anticancer Res; 2002; 22(6A):3409-14. PubMed ID: 12530096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
    Sparks AB; Morin PJ; Vogelstein B; Kinzler KW
    Cancer Res; 1998 Mar; 58(6):1130-4. PubMed ID: 9515795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis.
    Ficari F; Cama A; Valanzano R; Curia MC; Palmirotta R; Aceto G; Esposito DL; Crognale S; Lombardi A; Messerini L; Mariani-Costantini R; Tonelli F; Battista P
    Br J Cancer; 2000 Jan; 82(2):348-53. PubMed ID: 10646887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of APC/beta-catenin genes mutations and Wnt signalling pathway in desmoid-type fibromatosis.
    Jilong Y; Jian W; Xiaoyan Z; Xiaoqiu L; Xiongzeng Z
    Pathology; 2007 Jun; 39(3):319-25. PubMed ID: 17558858
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Expression and significance of APC, beta-catenin, C-myc, and Cyclin D1 proteins in colorectal carcinoma].
    Dai WB; Ren ZP; Chen WL; DU J; Shi Z; Tang DY
    Ai Zheng; 2007 Sep; 26(9):963-6. PubMed ID: 17927853
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis.
    Keller JJ; Offerhaus GJ; Drillenburg P; Caspers E; Musler A; Ristimäki A; Giardiello FM
    Clin Cancer Res; 2001 Dec; 7(12):4000-7. PubMed ID: 11751493
    [TBL] [Abstract][Full Text] [Related]  

  • 13. APC haploinsufficiency, but not CTNNB1 or CDH1 gene mutations, accounts for a fraction of familial adenomatous polyposis patients without APC truncating mutations.
    Venesio T; Balsamo A; Rondo-Spaudo M; Varesco L; Risio M; Ranzani GN
    Lab Invest; 2003 Dec; 83(12):1859-66. PubMed ID: 14691304
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional characterization of the novel APC N1026S variant associated with attenuated familial adenomatous polyposis.
    Menéndez M; González S; Obrador-Hevia A; Domínguez A; Pujol MJ; Valls J; Canela N; Blanco I; Torres A; Pineda-Lucena A; Moreno V; Bachs O; Capellá G
    Gastroenterology; 2008 Jan; 134(1):56-64. PubMed ID: 18166348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The expression of E-cadherin and catenins in colorectal tumours from familial adenomatous polyposis patients.
    El-Bahrawy MA; Talbot IC; Poulsom R; Jeffery R; Alison MR
    J Pathol; 2002 Sep; 198(1):69-76. PubMed ID: 12210065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing beta-catenin.
    Wang HL; Wang J; Xiao SY; Haydon R; Stoiber D; He TC; Bissonnette M; Hart J
    Int J Cancer; 2002 Oct; 101(4):301-10. PubMed ID: 12209953
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Frequent alterations of the beta-catenin and TCF-4 genes, but not of the APC gene, in colon cancers with high-frequency microsatellite instability.
    Fukushima H; Yamamoto H; Itoh F; Horiuchi S; Min Y; Iku S; Imai K
    J Exp Clin Cancer Res; 2001 Dec; 20(4):553-9. PubMed ID: 11876551
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
    Groves C; Lamlum H; Crabtree M; Williamson J; Taylor C; Bass S; Cuthbert-Heavens D; Hodgson S; Phillips R; Tomlinson I
    Am J Pathol; 2002 Jun; 160(6):2055-61. PubMed ID: 12057910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A; Kullmann F
    Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors).
    Alman BA; Li C; Pajerski ME; Diaz-Cano S; Wolfe HJ
    Am J Pathol; 1997 Aug; 151(2):329-34. PubMed ID: 9250146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.