BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 12529967)

  • 1. Phenoxodiol (2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl)), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex.
    Constantinou AI; Husband A
    Anticancer Res; 2002; 22(5):2581-5. PubMed ID: 12529967
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topoisomerase I/II selectivity among derivatives of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).
    Bridewell DJ; Finlay GJ; Baguley BC
    Anticancer Drug Des; 2001 Dec; 16(6):317-24. PubMed ID: 12375884
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
    Kim SA; Kwon Y; Kim JH; Muller MT; Chung IK
    Biochemistry; 1998 Nov; 37(46):16316-24. PubMed ID: 9819224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187.
    Wang L; Eastmond DA
    Environ Mol Mutagen; 2002; 39(4):348-56. PubMed ID: 12112387
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.
    Constantinou A; Stoner GD; Mehta R; Rao K; Runyan C; Moon R
    Nutr Cancer; 1995; 23(2):121-30. PubMed ID: 7644381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative and qualitative aspects of topoisomerase I and II alpha and beta in untreated and platinum/cyclophosphamide treated malignant ovarian tumors.
    van der Zee AG; de Jong S; Keith WN; Hollema H; Boonstra H; de Vries EG
    Cancer Res; 1994 Feb; 54(3):749-55. PubMed ID: 8306337
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II.
    Kawiak A; Piosik J; Stasilojc G; Gwizdek-Wisniewska A; Marczak L; Stobiecki M; Bigda J; Lojkowska E
    Toxicol Appl Pharmacol; 2007 Sep; 223(3):267-76. PubMed ID: 17618663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BN80927: a novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo.
    Demarquay D; Huchet M; Coulomb H; Lesueur-Ginot L; Lavergne O; Camara J; Kasprzyk PG; Prévost G; Bigg DC
    Cancer Res; 2004 Jul; 64(14):4942-9. PubMed ID: 15256467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequence-specific potentiation of topoisomerase II inhibitors by the histone deacetylase inhibitor suberoylanilide hydroxamic acid.
    Marchion DC; Bicaku E; Daud AI; Richon V; Sullivan DM; Munster PN
    J Cell Biochem; 2004 May; 92(2):223-37. PubMed ID: 15108350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer.
    Wang SJ; Peyrollier K; Bourguignon LY
    Arch Otolaryngol Head Neck Surg; 2007 Mar; 133(3):281-8. PubMed ID: 17372087
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suramin inhibits the phosphorylation and catalytic activity of DNA topoisomerase II in human lung cancer cells.
    Funayama Y; Nishio K; Takeda Y; Kubota N; Ohira T; Ohmori T; Ohta S; Ogasawara H; Hasegawa S; Saijo N
    Anticancer Res; 1993; 13(6A):1981-8. PubMed ID: 8297104
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells.
    Kao YH; Hsieh HP; Chitlimalla SK; Pan WY; Kuo CC; Tsai YC; Lin WH; Chuang SE; Chang JY
    Anticancer Drugs; 2008 Feb; 19(2):151-8. PubMed ID: 18176111
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors.
    Onda T; Toyoda E; Miyazaki O; Seno C; Kagaya S; Okamoto K; Nishikawa K
    Cancer Lett; 2008 Jan; 259(1):99-110. PubMed ID: 17998154
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II.
    Adjei AA; Charron M; Rowinsky EK; Svingen PA; Miller J; Reid JM; Sebolt-Leopold J; Ames MM; Kaufmann SH
    Clin Cancer Res; 1998 Mar; 4(3):683-91. PubMed ID: 9533538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel use for the comet assay: detection of topoisomerase II inhibitors.
    Salti GI; Das Gupta TK; Constantinou AI
    Anticancer Res; 2000; 20(5A):3189-93. PubMed ID: 11062742
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of eukaryotic DNA topoisomerase I and II activities by indoloquinolinedione derivatives.
    Riou JF; Helissey P; Grondard L; Giorgi-Renault S
    Mol Pharmacol; 1991 Nov; 40(5):699-706. PubMed ID: 1658605
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of anthracenyl-dipeptide conjugates as novel topoisomerase I and II inhibitors and their evaluation as potential anticancer drugs.
    Meikle I; Cummings J; Macpherson JS; Smyth JF
    Anticancer Drug Des; 1995 Oct; 10(7):515-27. PubMed ID: 7495476
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.
    Marchion DC; Bicaku E; Turner JG; Daud AI; Sullivan DM; Munster PN
    Clin Cancer Res; 2005 Dec; 11(23):8467-75. PubMed ID: 16322310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of catalytic topoisomerase II inhibitors to probe mechanisms of chemical-induced clastogenicity in Chinese hamster V79 cells.
    Snyder RD
    Environ Mol Mutagen; 2000; 35(1):13-21. PubMed ID: 10692223
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation of cytotoxicity and protein-associated DNA strand breaks for 2-(arylmethylamino)-1,3-propanediols.
    Dorr RT; Bellamy W; Liddil JD; Baker A; Bair KW
    Anticancer Drug Des; 1998 Oct; 13(7):825-35. PubMed ID: 9807165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.