BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 12531919)

  • 1. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice.
    Akamatsu Y; Monroe R; Dudley DD; Elkin SK; Gartner F; Talukder SR; Takahama Y; Alt FW; Bassing CH; Oettinger MA
    Proc Natl Acad Sci U S A; 2003 Feb; 100(3):1209-14. PubMed ID: 12531919
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development.
    Liang HE; Hsu LY; Cado D; Cowell LG; Kelsoe G; Schlissel MS
    Immunity; 2002 Nov; 17(5):639-51. PubMed ID: 12433370
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.
    Dudley DD; Sekiguchi J; Zhu C; Sadofsky MJ; Whitlow S; DeVido J; Monroe RJ; Bassing CH; Alt FW
    J Exp Med; 2003 Nov; 198(9):1439-50. PubMed ID: 14581608
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly.
    Kirch SA; Rathbun GA; Oettinger MA
    EMBO J; 1998 Aug; 17(16):4881-6. PubMed ID: 9707447
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex.
    Byrum JN; Zhao S; Rahman NS; Gwyn LM; Rodgers W; Rodgers KK
    Protein Sci; 2015 May; 24(5):861-73. PubMed ID: 25676158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination.
    West KL; Singha NC; De Ioannes P; Lacomis L; Erdjument-Bromage H; Tempst P; Cortes P
    Immunity; 2005 Aug; 23(2):203-12. PubMed ID: 16111638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAG1 and RAG2 in V(D)J recombination and transposition.
    Fugmann SD
    Immunol Res; 2001; 23(1):23-39. PubMed ID: 11417858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination.
    Landree MA; Wibbenmeyer JA; Roth DB
    Genes Dev; 1999 Dec; 13(23):3059-69. PubMed ID: 10601032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination.
    Qiu JX; Kale SB; Yarnell Schultz H; Roth DB
    Mol Cell; 2001 Jan; 7(1):77-87. PubMed ID: 11172713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Three-dimensional clustering of human RAG2 gene mutations in severe combined immune deficiency.
    Corneo B; Moshous D; Callebaut I; de Chasseval R; Fischer A; de Villartay JP
    J Biol Chem; 2000 Apr; 275(17):12672-5. PubMed ID: 10777560
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Partial reconstitution of V(D)J rearrangement and lymphocyte development in RAG-deficient mice expressing inducible, tetracycline-regulated RAG transgenes.
    Shockett PE; Zhou S; Hong X; Schatz DG
    Mol Immunol; 2004 Jan; 40(11):813-29. PubMed ID: 14687938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Function and control of recombination-activating gene activity.
    Alt FW; Rathbun G; Oltz E; Taccioli G; Shinkai Y
    Ann N Y Acad Sci; 1992 May; 651():277-94. PubMed ID: 1599127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. V(D)J recombinase activity in a subset of germinal center B lymphocytes.
    Han S; Dillon SR; Zheng B; Shimoda M; Schlissel MS; Kelsoe G
    Science; 1997 Oct; 278(5336):301-5. PubMed ID: 9323211
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The roles of the RAG1 and RAG2 "non-core" regions in V(D)J recombination and lymphocyte development.
    Jones JM; Simkus C
    Arch Immunol Ther Exp (Warsz); 2009; 57(2):105-16. PubMed ID: 19333736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immature Lymphocytes Inhibit
    Fisher MR; Rivera-Reyes A; Bloch NB; Schatz DG; Bassing CH
    J Immunol; 2017 Apr; 198(7):2943-2956. PubMed ID: 28213501
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex.
    Aidinis V; Dias DC; Gomez CA; Bhattacharyya D; Spanopoulou E; Santagata S
    J Immunol; 2000 Jun; 164(11):5826-32. PubMed ID: 10820261
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells.
    Han S; Zheng B; Schatz DG; Spanopoulou E; Kelsoe G
    Science; 1996 Dec; 274(5295):2094-7. PubMed ID: 8953043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The RAG2 C terminus suppresses genomic instability and lymphomagenesis.
    Deriano L; Chaumeil J; Coussens M; Multani A; Chou Y; Alekseyenko AV; Chang S; Skok JA; Roth DB
    Nature; 2011 Mar; 471(7336):119-23. PubMed ID: 21368836
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency.
    Pavel-Dinu M; Gardner CL; Nakauchi Y; Kawai T; Delmonte OM; Palterer B; Bosticardo M; Pala F; Viel S; Malech HL; Ghanim HY; Bode NM; Kurgan GL; Detweiler AM; Vakulskas CA; Neff NF; Sheikali A; Menezes ST; Chrobok J; Hernández González EM; Majeti R; Notarangelo LD; Porteus MH
    Blood Adv; 2024 Apr; 8(7):1820-1833. PubMed ID: 38096800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice.
    Talukder SR; Dudley DD; Alt FW; Takahama Y; Akamatsu Y
    Nucleic Acids Res; 2004; 32(15):4539-49. PubMed ID: 15328366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.