BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 12538021)

  • 1. Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell line.
    Stefańska B; Arciemiuk M; Bontemps-Gracz MM; Dzieduszycka M; Kupiec A; Martelli S; Borowski E
    Bioorg Med Chem; 2003 Feb; 11(4):561-72. PubMed ID: 12538021
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation.
    Stefańska B; Dzieduszycka M; Bontemps-Gracz MM; Borowski E; Martelli S; Supino R; Pratesi G; De Cesare M; Zunino F; Kuśnierczyk H; Radzikowski C
    J Med Chem; 1999 Sep; 42(18):3494-501. PubMed ID: 10479282
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of (dialkylamino)alkyl-disubstituted pyrimido[5,6,1- de]acridines, a novel group of anticancer agents active on a multidrug resistant cell line.
    Antonini I; Cola D; Polucci P; Bontemps-Gracz M; Borowski E; Martelli S
    J Med Chem; 1995 Aug; 38(17):3282-6. PubMed ID: 7650682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor evaluation of 2,5-disubstituted-indazolo[4, 3-gh]isoquinolin-6(2H)-ones (9-aza-anthrapyrazoles).
    Krapcho AP; Menta E; Oliva A; Di Domenico R; Fiocchi L; Maresch ME; Gallagher CE; Hacker MP; Beggiolin G; Giuliani FC; Pezzoni G; Spinelli S
    J Med Chem; 1998 Dec; 41(27):5429-44. PubMed ID: 9876113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship.
    Sami SM; Dorr RT; Sólyom AM; Alberts DS; Remers WA
    J Med Chem; 1995 Mar; 38(6):983-93. PubMed ID: 7699715
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 6,9-Bis[(aminoalkyl)amino]benzo[g]isoquinoline-5,10-diones. A novel class of chromophore-modified antitumor anthracene-9,10-diones: synthesis and antitumor evaluations.
    Krapcho AP; Petry ME; Getahun Z; Landi JJ; Stallman J; Polsenberg JF; Gallagher CE; Maresch MJ; Hacker MP; Giuliani FC
    J Med Chem; 1994 Mar; 37(6):828-37. PubMed ID: 8145234
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents.
    Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S
    J Med Chem; 2002 Jan; 45(3):696-702. PubMed ID: 11806721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2,7-Dihydro-3H-pyridazino[5,4,3-kl]acridin-3-one derivatives, novel type of cytotoxic agents active on multidrug-resistant cell lines. Synthesis and biological evaluation.
    Stefańska B; Bontemps-Gracz MM; Antonini I; Martelli S; Arciemiuk M; Piwkowska A; Rogacka D; Borowski E
    Bioorg Med Chem; 2005 Mar; 13(6):1969-75. PubMed ID: 15727851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA topoisomerase II-mediated interaction of doxorubicin and daunorubicin congeners with DNA.
    Bodley A; Liu LF; Israel M; Seshadri R; Koseki Y; Giuliani FC; Kirschenbaum S; Silber R; Potmesil M
    Cancer Res; 1989 Nov; 49(21):5969-78. PubMed ID: 2551497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
    Vanhuyse M; Kluza J; Tardy C; Otero G; Cuevas C; Bailly C; Lansiaux A
    Cancer Lett; 2005 Apr; 221(2):165-75. PubMed ID: 15808402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of 6-(9-hydroxy-5-methyl (and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazol-1-yl)picolinic amides as new olivacine derivatives.
    Landras C; Jasztold-Howorko R; Pierré A; Léonce S; Guilbaud N; Kraus-Berthier L; Guillonneau C; Rolland Y; Atassi G; Bisagni E
    Chem Pharm Bull (Tokyo); 1996 Nov; 44(11):2169-72. PubMed ID: 8945783
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines.
    Dzieduszycka M; Bontemps-Gracz MM; Stefańska B; Martelli S; Piwkowska A; Arciemiuk M; Borowski E
    Bioorg Med Chem; 2006 May; 14(9):2880-6. PubMed ID: 16458007
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2-[2'-(Dimethylamino)ethyl]-1,2-dihydro- 3H-dibenz[de,h]isoquinoline-1,3-diones with substituents at positions 4, 8, 9, 10, and 11. Synthesis, antitumor activity, and quantitative structure-activity relationships.
    Sami SM; Dorr RT; Alberts DS; Sólyom AM; Remers WA
    J Med Chem; 1996 Dec; 39(25):4978-87. PubMed ID: 8960558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anthrapyrazole anticancer agents. Synthesis and structure-activity relationships against murine leukemias.
    Showalter HD; Johnson JL; Hoftiezer JM; Turner WR; Werbel LM; Leopold WR; Shillis JL; Jackson RC; Elslager EF
    J Med Chem; 1987 Jan; 30(1):121-31. PubMed ID: 3806589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bbr 2778, an aza-anthracenedione endowed with preclinical anticancer activity and lack of delayed cardiotoxicity.
    Beggiolin G; Crippa L; Menta E; Manzotti C; Cavalletti E; Pezzoni G; Torriani D; Randisi E; Cavagnoli R; Sala F; Giuliani FC; Spinelli S
    Tumori; 2001; 87(6):407-16. PubMed ID: 11989596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
    Tardy C; Facompré M; Laine W; Baldeyrou B; García-Gravalos D; Francesch A; Mateo C; Pastor A; Jiménez JA; Manzanares I; Cuevas C; Bailly C
    Bioorg Med Chem; 2004 Apr; 12(7):1697-712. PubMed ID: 15028262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversal of multidrug resistance by a novel quinoline derivative, MS-209.
    Sato W; Fukazawa N; Nakanishi O; Baba M; Suzuki T; Yano O; Naito M; Tsuruo T
    Cancer Chemother Pharmacol; 1995; 35(4):271-7. PubMed ID: 7828268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. (R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
    Kirshenbaum MR; Chen SF; Behrens CH; Papp LM; Stafford MM; Sun JH; Behrens DL; Fredericks JR; Polkus ST; Sipple P
    Cancer Res; 1994 Apr; 54(8):2199-206. PubMed ID: 8174127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones.
    Kwak JH; Namgoong K; Jung JK; Han SB; Cho J; Kim HM; Park SG; Lee K; Kang JS; Lee H
    Arch Pharm Res; 2010 May; 33(5):663-7. PubMed ID: 20512462
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2,3-Dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione derivatives, a class of cytotoxic agents active on multidrug-resistant cell lines: synthesis, biological evaluation, and structure-activity relationships.
    Antonini I; Polucci P; Kelland LR; Menta E; Pescalli N; Martelli S
    J Med Chem; 1999 Jul; 42(14):2535-41. PubMed ID: 10411474
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.