BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 12538054)

  • 1. Intrinsic tryptophan fluorescence as a probe of metal and alpha-ketoglutarate binding to TfdA, a mononuclear non-heme iron dioxygenase.
    Dunning Hotopp JC; Auchtung TA; Hogan DA; Hausinger RP
    J Inorg Biochem; 2003 Jan; 93(1-2):66-70. PubMed ID: 12538054
    [TBL] [Abstract][Full Text] [Related]  

  • 2. X-ray absorption spectroscopic analysis of Fe(II) and Cu(II) forms of a herbicide-degrading alpha-ketoglutarate dioxygenase.
    Cosper NJ; Stålhandske CM; Saari RE; Hausinger RP; Scott RA
    J Biol Inorg Chem; 1999 Feb; 4(1):122-9. PubMed ID: 10499109
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Herbicide-degrading alpha-keto acid-dependent enzyme TfdA: metal coordination environment and mechanistic insights.
    Hegg EL; Whiting AK; Saari RE; McCracken J; Hausinger RP; Que L
    Biochemistry; 1999 Dec; 38(50):16714-26. PubMed ID: 10600135
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stopped-flow kinetic analysis of Escherichia coli taurine/alpha-ketoglutarate dioxygenase: interactions with alpha-ketoglutarate, taurine, and oxygen.
    Ryle MJ; Padmakumar R; Hausinger RP
    Biochemistry; 1999 Nov; 38(46):15278-86. PubMed ID: 10563813
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates.
    Elkins JM; Ryle MJ; Clifton IJ; Dunning Hotopp JC; Lloyd JS; Burzlaff NI; Baldwin JE; Hausinger RP; Roach PL
    Biochemistry; 2002 Apr; 41(16):5185-92. PubMed ID: 11955067
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate.
    Grzyska PK; Ryle MJ; Monterosso GR; Liu J; Ballou DP; Hausinger RP
    Biochemistry; 2005 Mar; 44(10):3845-55. PubMed ID: 15751960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Site-directed mutagenesis of 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase. Identification of residues involved in metallocenter formation and substrate binding.
    Hogan DA; Smith SR; Saari EA; McCracken J; Hausinger RP
    J Biol Chem; 2000 Apr; 275(17):12400-9. PubMed ID: 10777523
    [TBL] [Abstract][Full Text] [Related]  

  • 8. O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase.
    Ryle MJ; Liu A; Muthukumaran RB; Ho RY; Koehntop KD; McCracken J; Que L; Hausinger RP
    Biochemistry; 2003 Feb; 42(7):1854-62. PubMed ID: 12590572
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interconversion of two oxidized forms of taurine/alpha-ketoglutarate dioxygenase, a non-heme iron hydroxylase: evidence for bicarbonate binding.
    Ryle MJ; Koehntop KD; Liu A; Que L; Hausinger RP
    Proc Natl Acad Sci U S A; 2003 Apr; 100(7):3790-5. PubMed ID: 12642663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the 2,4-dichlorophenoxyacetate/alpha-ketoglutarate dioxygenase substrate-binding site by site-directed mutagenesis and mechanism-based inactivation.
    Dunning Hotopp JC; Hausinger RP
    Biochemistry; 2002 Aug; 41(31):9787-94. PubMed ID: 12146944
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism.
    Koehntop KD; Marimanikkuppam S; Ryle MJ; Hausinger RP; Que L
    J Biol Inorg Chem; 2006 Jan; 11(1):63-72. PubMed ID: 16320009
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli.
    Price JC; Barr EW; Tirupati B; Bollinger JM; Krebs C
    Biochemistry; 2003 Jun; 42(24):7497-508. PubMed ID: 12809506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).
    Chaplin VD; Valliere MA; Hangasky JA; Knapp MJ
    J Inorg Biochem; 2018 Jan; 178():63-69. PubMed ID: 29078149
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.
    Hangasky JA; Taabazuing CY; Valliere MA; Knapp MJ
    Metallomics; 2013 Apr; 5(4):287-301. PubMed ID: 23446356
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aziridine Formation by a Fe
    Bunno R; Awakawa T; Mori T; Abe I
    Angew Chem Int Ed Engl; 2021 Jul; 60(29):15827-15831. PubMed ID: 33973699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site.
    Bleijlevens B; Shivarattan T; Sedgwick B; Rigby SE; Matthews SJ
    J Inorg Biochem; 2007 Jul; 101(7):1043-8. PubMed ID: 17553567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein Flexibility of the α-Ketoglutarate-Dependent Oxygenase Factor-Inhibiting HIF-1: Implications for Substrate Binding, Catalysis, and Regulation.
    Martin CB; Chaplin VD; Eyles SJ; Knapp MJ
    Biochemistry; 2019 Oct; 58(39):4047-4057. PubMed ID: 31499004
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Global stability of an α-ketoglutarate-dependent dioxygenase (TauD) and its related complexes.
    Henderson KL; Li M; Martinez S; Lewis EA; Hausinger RP; Emerson JP
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt A):987-994. PubMed ID: 28214548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase.
    Grzyska PK; Müller TA; Campbell MG; Hausinger RP
    J Inorg Biochem; 2007 May; 101(5):797-808. PubMed ID: 17350690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Variations of the 2-His-1-carboxylate theme in mononuclear non-heme FeII oxygenases.
    Straganz GD; Nidetzky B
    Chembiochem; 2006 Oct; 7(10):1536-48. PubMed ID: 16858718
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.