BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

516 related articles for article (PubMed ID: 12538834)

  • 1. Interactions of the dipeptide ester prodrugs of acyclovir with the intestinal oligopeptide transporter: competitive inhibition of glycylsarcosine transport in human intestinal cell line-Caco-2.
    Anand BS; Patel J; Mitra AK
    J Pharmacol Exp Ther; 2003 Feb; 304(2):781-91. PubMed ID: 12538834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacokinetics of novel dipeptide ester prodrugs of acyclovir after oral administration: intestinal absorption and liver metabolism.
    Anand BS; Katragadda S; Mitra AK
    J Pharmacol Exp Ther; 2004 Nov; 311(2):659-67. PubMed ID: 15226381
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter.
    Han HK; Oh DM; Amidon GL
    Pharm Res; 1998 Sep; 15(9):1382-6. PubMed ID: 9755889
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.
    Han H; de Vrueh RL; Rhie JK; Covitz KM; Smith PL; Lee CP; Oh DM; Sadée W; Amidon GL
    Pharm Res; 1998 Aug; 15(8):1154-9. PubMed ID: 9706043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity.
    Santos C; Morais J; Gouveia L; de Clercq E; Pannecouque C; Nielsen CU; Steffansen B; Moreira R; Gomes P
    ChemMedChem; 2008 Jun; 3(6):970-8. PubMed ID: 18389514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
    Ganapathy ME; Huang W; Wang H; Ganapathy V; Leibach FH
    Biochem Biophys Res Commun; 1998 May; 246(2):470-5. PubMed ID: 9610386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dipeptide monoester ganciclovir prodrugs for transscleral drug delivery: targeting the oligopeptide transporter on rabbit retina.
    Kansara V; Hao Y; Mitra AK
    J Ocul Pharmacol Ther; 2007 Aug; 23(4):321-34. PubMed ID: 17803430
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recognition of L-amino acid ester compounds by rat peptide transporters PEPT1 and PEPT2.
    Sawada K; Terada T; Saito H; Hashimoto Y; Inui KI
    J Pharmacol Exp Ther; 1999 Nov; 291(2):705-9. PubMed ID: 10525090
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2.
    de Vrueh RL; Smith PL; Lee CP
    J Pharmacol Exp Ther; 1998 Sep; 286(3):1166-70. PubMed ID: 9732374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid prodrugs of acyclovir as possible antiviral agents against ocular HSV-1 infections: interactions with the neutral and cationic amino acid transporter on the corneal epithelium.
    Anand BS; Katragadda S; Nashed YE; Mitra AK
    Curr Eye Res; 2004; 29(2-3):153-66. PubMed ID: 15512962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel dipeptide prodrugs of acyclovir for ocular herpes infections: Bioreversion, antiviral activity and transport across rabbit cornea.
    Anand B; Nashed Y; Mitra A
    Curr Eye Res; 2003; 26(3-4):151-63. PubMed ID: 12815543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conjugation of dipeptide to fluorescent dyes enhances its affinity for a dipeptide transporter (PEPT1) in human intestinal Caco-2 cells.
    Abe H; Satoh M; Miyauchi S; Shuto S; Matsuda A; Kamo N
    Bioconjug Chem; 1999; 10(1):24-31. PubMed ID: 9893960
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.
    Song X; Vig BS; Lorenzi PL; Drach JC; Townsend LB; Amidon GL
    J Med Chem; 2005 Feb; 48(4):1274-7. PubMed ID: 15715497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.
    Guo A; Hu P; Balimane PV; Leibach FH; Sinko PJ
    J Pharmacol Exp Ther; 1999 Apr; 289(1):448-54. PubMed ID: 10087037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir.
    Balimane PV; Tamai I; Guo A; Nakanishi T; Kitada H; Leibach FH; Tsuji A; Sinko PJ
    Biochem Biophys Res Commun; 1998 Sep; 250(2):246-51. PubMed ID: 9753615
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Uptake of cyclic dipeptide by PEPT1 in Caco-2 cells: phenolic hydroxyl group of substrate enhances affinity for PEPT1.
    Mizuma T; Narasaka T; Awazu S
    J Pharm Pharmacol; 2002 Sep; 54(9):1293-6. PubMed ID: 12356285
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of corneal permeation of L-valyl ester of acyclovir: targeting the oligopeptide transporter on the rabbit cornea.
    Anand BS; Mitra AK
    Pharm Res; 2002 Aug; 19(8):1194-202. PubMed ID: 12240946
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Propylene glycol-linked amino acid/dipeptide diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability, and pharmacokinetics.
    Cao F; Gao Y; Wang M; Fang L; Ping Q
    Mol Pharm; 2013 Apr; 10(4):1378-87. PubMed ID: 23339520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
    Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
    Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simultaneous modulation of transport and metabolism of acyclovir prodrugs across rabbit cornea: An approach involving enzyme inhibitors.
    Katragadda S; Talluri RS; Mitra AK
    Int J Pharm; 2006 Aug; 320(1-2):104-13. PubMed ID: 16720085
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.