These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 12540638)

  • 1. The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.
    Nielsen EM; Hansen L; Carstensen B; Echwald SM; Drivsholm T; Glümer C; Thorsteinsson B; Borch-Johnsen K; Hansen T; Pedersen O
    Diabetes; 2003 Feb; 52(2):573-7. PubMed ID: 12540638
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
    Villareal DT; Koster JC; Robertson H; Akrouh A; Miyake K; Bell GI; Patterson BW; Nichols CG; Polonsky KS
    Diabetes; 2009 Aug; 58(8):1869-78. PubMed ID: 19491206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The E23K variant in the Kir6.2 subunit of the ATP-sensitive K+ channel does not augment impaired glucose tolerance in Caribbean subjects with a family history of type 2 diabetes.
    Ezenwaka C; Kalloo R; Uhlig M; Schwenk R; Eckel J
    J Endocrinol; 2005 Jun; 185(3):439-44. PubMed ID: 15930170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study.
    Doi Y; Kubo M; Ninomiya T; Yonemoto K; Iwase M; Arima H; Hata J; Tanizaki Y; Iida M; Kiyohara Y
    Diabetes; 2007 Nov; 56(11):2829-33. PubMed ID: 17965318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.
    Gloyn AL; Weedon MN; Owen KR; Turner MJ; Knight BA; Hitman G; Walker M; Levy JC; Sampson M; Halford S; McCarthy MI; Hattersley AT; Frayling TM
    Diabetes; 2003 Feb; 52(2):568-72. PubMed ID: 12540637
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.
    Florez JC; Jablonski KA; Kahn SE; Franks PW; Dabelea D; Hamman RF; Knowler WC; Nathan DM; Altshuler D
    Diabetes; 2007 Feb; 56(2):531-6. PubMed ID: 17259403
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.
    Sesti G; Laratta E; Cardellini M; Andreozzi F; Del Guerra S; Irace C; Gnasso A; Grupillo M; Lauro R; Hribal ML; Perticone F; Marchetti P
    J Clin Endocrinol Metab; 2006 Jun; 91(6):2334-9. PubMed ID: 16595597
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.
    Florez JC; Burtt N; de Bakker PI; Almgren P; Tuomi T; Holmkvist J; Gaudet D; Hudson TJ; Schaffner SF; Daly MJ; Hirschhorn JN; Groop L; Altshuler D
    Diabetes; 2004 May; 53(5):1360-8. PubMed ID: 15111507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population-based studies and meta-analyses.
    van Dam RM; Hoebee B; Seidell JC; Schaap MM; de Bruin TW; Feskens EJ
    Diabet Med; 2005 May; 22(5):590-8. PubMed ID: 15842514
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of genetic susceptibility of KCNJ11 E23K polymorphism with risk of type 2 diabetes in an Iranian population.
    Keshavarz P; Habibipour R; Ghasemi M; Kazemnezhad E; Alizadeh M; Omami MH
    Endocr Res; 2014; 39(3):120-5. PubMed ID: 24460047
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of single nucleotide polymorphisms in K(ATP) channel genes on type 2 diabetes in a Turkish population.
    Gonen MS; Arikoglu H; Erkoc Kaya D; Ozdemir H; Ipekci SH; Arslan A; Kayis SA; Gogebakan B
    Arch Med Res; 2012 May; 43(4):317-23. PubMed ID: 22704848
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K(+) channel in the beta-cell.
    't Hart LM; van Haeften TW; Dekker JM; Bot M; Heine RJ; Maassen JA
    Diabetes; 2002 Oct; 51(10):3135-8. PubMed ID: 12351459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association between KCNJ11 E23K genotype and cardiovascular and glucose metabolism phenotypes in older men and women.
    Yi Y; Dongmei L; Phares DA; Weiss EP; Brandauer J; Hagberg JM
    Exp Physiol; 2008 Jan; 93(1):95-103. PubMed ID: 17720745
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes.
    Chistiakov DA; Potapov VA; Khodirev DC; Shamkhalova MS; Shestakova MV; Nosikov VV
    Acta Diabetol; 2009 Mar; 46(1):43-9. PubMed ID: 18758683
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polymorphism E23K (rs5219) in the KCNJ11 gene in Euro-Brazilian subjects with type 1 and 2 diabetes.
    Souza SW; Alcazar LP; Arakaki PA; Santos-Weiss IC; Alberton D; Picheth G; Rego FG
    Genet Mol Res; 2017 Apr; 16(2):. PubMed ID: 28387875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians.
    Hani EH; Boutin P; Durand E; Inoue H; Permutt MA; Velho G; Froguel P
    Diabetologia; 1998 Dec; 41(12):1511-5. PubMed ID: 9867219
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prediabetes is associated with genetic variations in the gene encoding the Kir6.2 subunit of the pancreatic ATP-sensitive potassium channel (KCNJ11): A case-control study in a Han Chinese youth population.
    Xu M; Hu H; Deng D; Chen M; Xu Z; Wang Y
    J Diabetes; 2018 Feb; 10(2):121-129. PubMed ID: 28449408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus.
    Shaat N; Ekelund M; Lernmark A; Ivarsson S; Almgren P; Berntorp K; Groop L
    Diabetologia; 2005 Dec; 48(12):2544-51. PubMed ID: 16320083
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E23K variant in KCNJ11 gene is associated with susceptibility to type 2 diabetes in the Mauritanian population.
    Abdelhamid I; Lasram K; Meiloud G; Ben Halim N; Kefi R; Samb A; Abdelhak S; Houmeida A
    Prim Care Diabetes; 2014 Jul; 8(2):171-5. PubMed ID: 24332549
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.
    Barber TM; Bennett AJ; Gloyn AL; Groves CJ; Sovio U; Ruokonen A; Martikainen H; Pouta A; Taponen S; Weedon MN; Hartikainen AL; Wass JA; Järvelin MR; Zeggini E; Franks S; McCarthy MI
    Eur J Hum Genet; 2007 Jun; 15(6):679-84. PubMed ID: 17342155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.