228 related articles for article (PubMed ID: 12543662)
1. Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.
Mann PA; Parmegiani RM; Wei SQ; Mendrick CA; Li X; Loebenberg D; DiDomenico B; Hare RS; Walker SS; McNicholas PM
Antimicrob Agents Chemother; 2003 Feb; 47(2):577-81. PubMed ID: 12543662
[TBL] [Abstract][Full Text] [Related]
2. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.
Mellado E; Garcia-Effron G; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2004 Jul; 48(7):2747-50. PubMed ID: 15215142
[TBL] [Abstract][Full Text] [Related]
3. Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms.
Garcia-Rubio R; Alcazar-Fuoli L; Monteiro MC; Monzon S; Cuesta I; Pelaez T; Mellado E
Antimicrob Agents Chemother; 2018 Jun; 62(6):. PubMed ID: 29632011
[TBL] [Abstract][Full Text] [Related]
4. A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus.
Diaz-Guerra TM; Mellado E; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2003 Mar; 47(3):1120-4. PubMed ID: 12604551
[TBL] [Abstract][Full Text] [Related]
5. Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds.
Munayyer HK; Mann PA; Chau AS; Yarosh-Tomaine T; Greene JR; Hare RS; Heimark L; Palermo RE; Loebenberg D; McNicholas PM
Antimicrob Agents Chemother; 2004 Oct; 48(10):3690-6. PubMed ID: 15388421
[TBL] [Abstract][Full Text] [Related]
6. Genomic perspective of triazole resistance in clinical and environmental Aspergillus fumigatus isolates without cyp51A mutations.
Sharma C; Nelson-Sathi S; Singh A; Radhakrishna Pillai M; Chowdhary A
Fungal Genet Biol; 2019 Nov; 132():103265. PubMed ID: 31465846
[TBL] [Abstract][Full Text] [Related]
7. Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus.
Krishnan-Natesan S; Chandrasekar PH; Alangaden GJ; Manavathu EK
Int J Antimicrob Agents; 2008 Dec; 32(6):519-24. PubMed ID: 18775650
[TBL] [Abstract][Full Text] [Related]
8. Point Mutation or Overexpression of Aspergillus fumigatus
Handelman M; Meir Z; Scott J; Shadkchan Y; Liu W; Ben-Ami R; Amich J; Osherov N
Antimicrob Agents Chemother; 2021 Sep; 65(10):e0125221. PubMed ID: 34310208
[TBL] [Abstract][Full Text] [Related]
9. Molecular typing and in-vitro activity of azoles against clinical isolates of Aspergillus fumigatus and A. niger in Japan.
Asano M; Kano R; Makimura K; Hasegawa A; Kamata H
J Infect Chemother; 2011 Aug; 17(4):483-6. PubMed ID: 21203794
[TBL] [Abstract][Full Text] [Related]
10. Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India.
Chowdhary A; Kathuria S; Randhawa HS; Gaur SN; Klaassen CH; Meis JF
J Antimicrob Chemother; 2012 Feb; 67(2):362-6. PubMed ID: 22028200
[TBL] [Abstract][Full Text] [Related]
11. Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.
Mellado E; Garcia-Effron G; Buitrago MJ; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2005 Jun; 49(6):2536-8. PubMed ID: 15917566
[TBL] [Abstract][Full Text] [Related]
12. Mutations in
Rybak JM; Ge W; Wiederhold NP; Parker JE; Kelly SL; Rogers PD; Fortwendel JR
mBio; 2019 Apr; 10(2):. PubMed ID: 30940706
[No Abstract] [Full Text] [Related]
13. First determination of azole resistance in Aspergillus fumigatus strains carrying the TR34/L98H mutations in Turkey.
Özmerdiven GE; Ak S; Ener B; Ağca H; Cilo BD; Tunca B; Akalın H
J Infect Chemother; 2015 Aug; 21(8):581-6. PubMed ID: 26048062
[TBL] [Abstract][Full Text] [Related]
14. Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma.
Chen J; Li H; Li R; Bu D; Wan Z
J Antimicrob Chemother; 2005 Jan; 55(1):31-7. PubMed ID: 15563516
[TBL] [Abstract][Full Text] [Related]
15. Investigation of Azole Resistance Involving
Ghorbel D; Amouri I; Khemekhem N; Neji S; Trabelsi H; Elloumi M; Sellami H; Makni F; Ayadi A; Hadrich I
Pol J Microbiol; 2024 Jun; 73(2):131-142. PubMed ID: 38700908
[TBL] [Abstract][Full Text] [Related]
16. Azole resistant Aspergillus fumigatus: an emerging problem.
Lelièvre L; Groh M; Angebault C; Maherault AC; Didier E; Bougnoux ME
Med Mal Infect; 2013 Apr; 43(4):139-45. PubMed ID: 23562488
[TBL] [Abstract][Full Text] [Related]
17. Elevated MIC Values of Imidazole Drugs against Aspergillus fumigatus Isolates with TR
Chen Y; Li Z; Han X; Tian S; Zhao J; Chen F; Su X; Zhao J; Zou Z; Gong Y; Qu F; Qiu G; Wang S; Jia X; Lu Z; Hu M; Huang L; Verweij PE; Han L
Antimicrob Agents Chemother; 2018 May; 62(5):. PubMed ID: 29507067
[TBL] [Abstract][Full Text] [Related]
18. In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus.
Warrilow AG; Parker JE; Price CL; Nes WD; Kelly SL; Kelly DE
Antimicrob Agents Chemother; 2015 Dec; 59(12):7771-8. PubMed ID: 26459890
[TBL] [Abstract][Full Text] [Related]
19. In vitro resistance of Aspergillus fumigatus to azole farm fungicide.
Kano R; Sobukawa H; Murayama SY; Hirose D; Tanaka Y; Kosuge Y; Hasegawa A; Kamata H
J Infect Chemother; 2016 Mar; 22(3):133-6. PubMed ID: 26711232
[TBL] [Abstract][Full Text] [Related]
20. Genotype-phenotype complexity of the TR46/Y121F/T289A cyp51A azole resistance mechanism in Aspergillus fumigatus.
Snelders E; Camps SM; Karawajczyk A; Rijs AJ; Zoll J; Verweij PE; Melchers WJ
Fungal Genet Biol; 2015 Sep; 82():129-35. PubMed ID: 26092193
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]