These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1903 related articles for article (PubMed ID: 12543789)

  • 1. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN; Easton J; Huang S; Veverka KA; Germain GS; Harwood FC; Houghton PJ
    Cancer Res; 2003 Jan; 63(2):364-74. PubMed ID: 12543789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling.
    Thimmaiah KN; Easton JB; Houghton PJ
    Cancer Res; 2010 Mar; 70(5):2000-9. PubMed ID: 20179209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB; Müller FU; Bergmann MW; Li P; Wang Y; Schmitz W; Dietz R; von Harsdorf R
    Circulation; 2001 Oct; 104(17):2088-94. PubMed ID: 11673351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.
    Sivaprasad U; Fleming J; Verma PS; Hogan KA; Desury G; Cohick WS
    Endocrinology; 2004 Sep; 145(9):4213-21. PubMed ID: 15192040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C; Rahmani M; Dai Y; Conrad D; Krystal G; Dent P; Grant S
    Cancer Res; 2003 Apr; 63(8):1822-33. PubMed ID: 12702569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
    Chaudhary LR; Hruska KA
    J Cell Biochem; 2001 Mar; 81(2):304-11. PubMed ID: 11241670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M; Morelli C; Mauro L; Andò S; Surmacz E
    Cancer Res; 2001 Sep; 61(18):6747-54. PubMed ID: 11559546
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anchorage-independent activation of mitogen-activated protein kinase through phosphatidylinositol-3 kinase by insulin-like growth factor I.
    Suzuki K; Takahashi K
    Biochem Biophys Res Commun; 2000 May; 272(1):111-5. PubMed ID: 10872812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells.
    Tsakiridis T; Tsiani E; Lekas P; Bergman A; Cherepanov V; Whiteside C; Downey GP
    Biochem Biophys Res Commun; 2001 Oct; 288(1):205-11. PubMed ID: 11594774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
    Kurihara S; Hakuno F; Takahashi S
    Endocr J; 2000 Dec; 47(6):739-51. PubMed ID: 11228049
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell cycle progression and activation of Akt kinase are required for insulin-like growth factor I-mediated suppression of apoptosis in granulosa cells.
    Hu CL; Cowan RG; Harman RM; Quirk SM
    Mol Endocrinol; 2004 Feb; 18(2):326-38. PubMed ID: 14593075
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.
    Tognon C; Garnett M; Kenward E; Kay R; Morrison K; Sorensen PH
    Cancer Res; 2001 Dec; 61(24):8909-16. PubMed ID: 11751416
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line.
    Sautin YY; Crawford JM; Svetlov SI
    Am J Physiol Cell Physiol; 2001 Dec; 281(6):C2010-9. PubMed ID: 11698260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor I-mediated inhibition of pancreatic beta-cell death.
    Liu W; Chin-Chance C; Lee EJ; Lowe WL
    Endocrinology; 2002 Oct; 143(10):3802-12. PubMed ID: 12239091
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downstream effectors of oncogenic ras in multiple myeloma cells.
    Hu L; Shi Y; Hsu JH; Gera J; Van Ness B; Lichtenstein A
    Blood; 2003 Apr; 101(8):3126-35. PubMed ID: 12515720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
    Campbell M; Allen WE; Sawyer C; Vanhaesebroeck B; Trimble ER
    Circ Res; 2004 Aug; 95(4):380-8. PubMed ID: 15242975
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene.
    Agazie Y; Ischenko I; Hayman M
    Oncogene; 2002 Jan; 21(5):697-707. PubMed ID: 11850798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O; Cantley LC
    Exp Cell Res; 2004 Jul; 297(1):224-34. PubMed ID: 15194438
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK; Graab U; Fulda S
    Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Up-regulation of urokinase-type plasminogen activator by insulin-like growth factor-I depends upon phosphatidylinositol-3 kinase and mitogen-activated protein kinase kinase.
    Dunn SE; Torres JV; Oh JS; Cykert DM; Barrett JC
    Cancer Res; 2001 Feb; 61(4):1367-74. PubMed ID: 11245436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 96.