284 related articles for article (PubMed ID: 12543805)
1. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability.
Piboonniyom SO; Duensing S; Swilling NW; Hasskarl J; Hinds PW; Münger K
Cancer Res; 2003 Jan; 63(2):476-83. PubMed ID: 12543805
[TBL] [Abstract][Full Text] [Related]
2. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Ramirez RD; Sheridan S; Girard L; Sato M; Kim Y; Pollack J; Peyton M; Zou Y; Kurie JM; Dimaio JM; Milchgrub S; Smith AL; Souza RF; Gilbey L; Zhang X; Gandia K; Vaughan MB; Wright WE; Gazdar AF; Shay JW; Minna JD
Cancer Res; 2004 Dec; 64(24):9027-34. PubMed ID: 15604268
[TBL] [Abstract][Full Text] [Related]
3. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
Kiyono T; Foster SA; Koop JI; McDougall JK; Galloway DA; Klingelhutz AJ
Nature; 1998 Nov; 396(6706):84-8. PubMed ID: 9817205
[TBL] [Abstract][Full Text] [Related]
4. Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Zhang H; Jin Y; Chen X; Jin C; Law S; Tsao SW; Kwong YL
Cancer Lett; 2007 Jan; 245(1-2):184-94. PubMed ID: 16488074
[TBL] [Abstract][Full Text] [Related]
5. Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.
Harada H; Nakagawa H; Oyama K; Takaoka M; Andl CD; Jacobmeier B; von Werder A; Enders GH; Opitz OG; Rustgi AK
Mol Cancer Res; 2003 Aug; 1(10):729-38. PubMed ID: 12939398
[TBL] [Abstract][Full Text] [Related]
6. Keratinocyte growth conditions modulate telomerase expression, senescence, and immortalization by human papillomavirus type 16 E6 and E7 oncogenes.
Fu B; Quintero J; Baker CC
Cancer Res; 2003 Nov; 63(22):7815-24. PubMed ID: 14633708
[TBL] [Abstract][Full Text] [Related]
7. Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.
Morris M; Hepburn P; Wynford-Thomas D
Oncogene; 2002 Jun; 21(27):4277-88. PubMed ID: 12082615
[TBL] [Abstract][Full Text] [Related]
8. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
[TBL] [Abstract][Full Text] [Related]
9. Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.
Takaoka M; Harada H; Deramaudt TB; Oyama K; Andl CD; Johnstone CN; Rhoades B; Enders GH; Opitz OG; Nakagawa H
Oncogene; 2004 Sep; 23(40):6760-8. PubMed ID: 15273725
[TBL] [Abstract][Full Text] [Related]
10. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.
Bartkova J; Lukas J; Guldberg P; Alsner J; Kirkin AF; Zeuthen J; Bartek J
Cancer Res; 1996 Dec; 56(23):5475-83. PubMed ID: 8968104
[TBL] [Abstract][Full Text] [Related]
11. Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7.
Sdek P; Zhang ZY; Cao J; Pan HY; Chen WT; Zheng JW
Int J Oral Maxillofac Surg; 2006 Jul; 35(7):653-7. PubMed ID: 16513324
[TBL] [Abstract][Full Text] [Related]
12. Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38.
Gabet AS; Accardi R; Bellopede A; Popp S; Boukamp P; Sylla BS; Londoño-Vallejo JA; Tommasino M
FASEB J; 2008 Feb; 22(2):622-32. PubMed ID: 17898088
[TBL] [Abstract][Full Text] [Related]
13. Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.
Fuxe J; Akusjärvi G; Goike HM; Roos G; Collins VP; Pettersson RF
Cell Growth Differ; 2000 Jul; 11(7):373-84. PubMed ID: 10939591
[TBL] [Abstract][Full Text] [Related]
14. p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells.
Jarrard DF; Sarkar S; Shi Y; Yeager TR; Magrane G; Kinoshita H; Nassif N; Meisner L; Newton MA; Waldman FM; Reznikoff CA
Cancer Res; 1999 Jun; 59(12):2957-64. PubMed ID: 10383161
[TBL] [Abstract][Full Text] [Related]
15. Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells.
Zhuang ZH; Tsao SW; Deng W; Wang JD; Xia HH; He H; Feng HC; Wang LD; Gu Q; Lam SK; Lin MC; Kung HF; Wong BC
J Gastroenterol Hepatol; 2008 Oct; 23(10):1613-20. PubMed ID: 18717758
[TBL] [Abstract][Full Text] [Related]
16. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Rheinwald JG; Hahn WC; Ramsey MR; Wu JY; Guo Z; Tsao H; De Luca M; Catricalà C; O'Toole KM
Mol Cell Biol; 2002 Jul; 22(14):5157-72. PubMed ID: 12077343
[TBL] [Abstract][Full Text] [Related]
17. Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
Wadhwa R; Takano S; Taira K; Kaul SC
J Gene Med; 2004 Apr; 6(4):439-44. PubMed ID: 15079818
[TBL] [Abstract][Full Text] [Related]
18. Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine.
McGregor F; Muntoni A; Fleming J; Brown J; Felix DH; MacDonald DG; Parkinson EK; Harrison PR
Cancer Res; 2002 Aug; 62(16):4757-66. PubMed ID: 12183435
[TBL] [Abstract][Full Text] [Related]
19. Analysis of p53, p16(INK4a), pRb and Cyclin D1 expression and human papillomavirus in primary ovarian serous carcinomas.
Bilyk OO; Pande NT; Buchynska LG
Exp Oncol; 2011 Sep; 33(3):150-6. PubMed ID: 21956468
[TBL] [Abstract][Full Text] [Related]
20. Association of p16(INK4a) and pRb inactivation with immortalization of human cells.
Tsutsui T; Kumakura S; Yamamoto A; Kanai H; Tamura Y; Kato T; Anpo M; Tahara H; Barrett JC
Carcinogenesis; 2002 Dec; 23(12):2111-7. PubMed ID: 12507935
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]