BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 12551923)

  • 1. Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition.
    Tran NH; Frost JA
    J Biol Chem; 2003 Mar; 278(13):11221-6. PubMed ID: 12551923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338.
    King AJ; Sun H; Diaz B; Barnard D; Miao W; Bagrodia S; Marshall MS
    Nature; 1998 Nov; 396(6707):180-3. PubMed ID: 9823899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms.
    Tran NH; Wu X; Frost JA
    J Biol Chem; 2005 Apr; 280(16):16244-53. PubMed ID: 15710605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.
    Yip-Schneider MT; Miao W; Lin A; Barnard DS; Tzivion G; Marshall MS
    Biochem J; 2000 Oct; 351(Pt 1):151-9. PubMed ID: 10998357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
    Coles LC; Shaw PE
    Oncogene; 2002 Mar; 21(14):2236-44. PubMed ID: 11948406
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association.
    Jin S; Zhuo Y; Guo W; Field J
    J Biol Chem; 2005 Jul; 280(26):24698-705. PubMed ID: 15849194
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak.
    Sun H; King AJ; Diaz HB; Marshall MS
    Curr Biol; 2000 Mar; 10(5):281-4. PubMed ID: 10712905
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src.
    Zimmermann S; Rommel C; Ziogas A; Lovric J; Moelling K; Radziwill G
    Oncogene; 1997 Sep; 15(13):1503-11. PubMed ID: 9380402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1.
    Zang M; Hayne C; Luo Z
    J Biol Chem; 2002 Feb; 277(6):4395-405. PubMed ID: 11733498
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins.
    Frost JA; Steen H; Shapiro P; Lewis T; Ahn N; Shaw PE; Cobb MH
    EMBO J; 1997 Nov; 16(21):6426-38. PubMed ID: 9351825
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.
    Zhang BH; Tang ED; Zhu T; Greenberg ME; Vojtek AB; Guan KL
    J Biol Chem; 2001 Aug; 276(34):31620-6. PubMed ID: 11410590
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Negative regulation of the serine/threonine kinase B-Raf by Akt.
    Guan KL; Figueroa C; Brtva TR; Zhu T; Taylor J; Barber TD; Vojtek AB
    J Biol Chem; 2000 Sep; 275(35):27354-9. PubMed ID: 10869359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase.
    Fabian JR; Daar IO; Morrison DK
    Mol Cell Biol; 1993 Nov; 13(11):7170-9. PubMed ID: 7692235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation.
    Hekman M; Fischer A; Wennogle LP; Wang YK; Campbell SL; Rapp UR
    FEBS Lett; 2005 Jan; 579(2):464-8. PubMed ID: 15642359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autoregulation of the Raf-1 serine/threonine kinase.
    Cutler RE; Stephens RM; Saracino MR; Morrison DK
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9214-9. PubMed ID: 9689060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Raf in vascular protection from distinct apoptotic stimuli.
    Alavi A; Hood JD; Frausto R; Stupack DG; Cheresh DA
    Science; 2003 Jul; 301(5629):94-6. PubMed ID: 12843393
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src.
    King AJ; Wireman RS; Hamilton M; Marshall MS
    FEBS Lett; 2001 May; 497(1):6-14. PubMed ID: 11376654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338.
    Chaudhary A; King WG; Mattaliano MD; Frost JA; Diaz B; Morrison DK; Cobb MH; Marshall MS; Brugge JS
    Curr Biol; 2000 May; 10(9):551-4. PubMed ID: 10801448
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway.
    Chie L; Amar S; Kung HF; Lin MC; Chen H; Chung DL; Adler V; Ronai Z; Friedman FK; Robinson RC; Kovac C; Brandt-Rauf PW; Yamaizumi Z; Michl J; Pincus MR
    Cancer Chemother Pharmacol; 2000; 45(6):441-9. PubMed ID: 10854130
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of Raf through phosphorylation and N terminus-C terminus interaction.
    Chong H; Guan KL
    J Biol Chem; 2003 Sep; 278(38):36269-76. PubMed ID: 12865432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.