BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 12552344)

  • 1. Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5.
    Ziemer LS; Evans SM; Kachur AV; Shuman AL; Cardi CA; Jenkins WT; Karp JS; Alavi A; Dolbier WR; Koch CJ
    Eur J Nucl Med Mol Imaging; 2003 Feb; 30(2):259-66. PubMed ID: 12552344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 18F-EF5: a new PET tracer for imaging hypoxia in head and neck cancer.
    Komar G; Seppänen M; Eskola O; Lindholm P; Grönroos TJ; Forsback S; Sipilä H; Evans SM; Solin O; Minn H
    J Nucl Med; 2008 Dec; 49(12):1944-51. PubMed ID: 18997048
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1.
    Evans SM; Kachur AV; Shiue CY; Hustinx R; Jenkins WT; Shive GG; Karp JS; Alavi A; Lord EM; Dolbier WR; Koch CJ
    J Nucl Med; 2000 Feb; 41(2):327-36. PubMed ID: 10688119
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft model.
    Chitneni SK; Bida GT; Yuan H; Palmer GM; Hay MP; Melcher T; Wilson WR; Zalutsky MR; Dewhirst MW
    J Nucl Med; 2013 Aug; 54(8):1339-46. PubMed ID: 23740105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models.
    Chitneni SK; Bida GT; Zalutsky MR; Dewhirst MW
    J Nucl Med; 2014 Jul; 55(7):1192-7. PubMed ID: 24854792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: comparative measurements using EF5 binding and the Eppendorf needle electrode.
    Jenkins WT; Evans SM; Koch CJ
    Int J Radiat Oncol Biol Phys; 2000 Mar; 46(4):1005-17. PubMed ID: 10705024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biodistribution and dosimetry of (18)F-EF5 in cancer patients with preliminary comparison of (18)F-EF5 uptake versus EF5 binding in human glioblastoma.
    Koch CJ; Scheuermann JS; Divgi C; Judy KD; Kachur AV; Freifelder R; Reddin JS; Karp J; Stubbs JB; Hahn SM; Driesbaugh J; Smith D; Prendergast S; Evans SM
    Eur J Nucl Med Mol Imaging; 2010 Nov; 37(11):2048-59. PubMed ID: 20585774
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.
    Silvola JM; Saraste A; Forsback S; Laine VJ; Saukko P; Heinonen SE; Ylä-Herttuala S; Roivainen A; Knuuti J
    Arterioscler Thromb Vasc Biol; 2011 May; 31(5):1011-5. PubMed ID: 21372297
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.
    Koch CJ; Hahn SM; Rockwell K; Covey JM; McKenna WG; Evans SM
    Cancer Chemother Pharmacol; 2001 Sep; 48(3):177-87. PubMed ID: 11592338
    [TBL] [Abstract][Full Text] [Related]  

  • 10.
    Qian Y; Von Eyben R; Liu Y; Chin FT; Miao Z; Apte S; Carter JN; Binkley MS; Pollom EL; Harris JP; Prionas ND; Kissel M; Simmons A; Diehn M; Shultz DB; Brown JM; Maxim PG; Koong AC; Graves EE; Loo BW
    Int J Radiat Oncol Biol Phys; 2018 Nov; 102(4):1183-1192. PubMed ID: 29859786
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors.
    Laughlin KM; Evans SM; Jenkins WT; Tracy M; Chan CY; Lord EM; Koch CJ
    J Pharmacol Exp Ther; 1996 May; 277(2):1049-57. PubMed ID: 8627516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure.
    Dolbier WR; Li AR; Koch CJ; Shiue CY; Kachur AV
    Appl Radiat Isot; 2001 Jan; 54(1):73-80. PubMed ID: 11144255
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 18F-EF5 PET Is Predictive of Response to Fractionated Radiotherapy in Preclinical Tumor Models.
    Ali R; Apte S; Vilalta M; Subbarayan M; Miao Z; Chin FT; Graves EE
    PLoS One; 2015; 10(10):e0139425. PubMed ID: 26431331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tracer level electrophilic synthesis and pharmacokinetics of the hypoxia tracer [(18)F]EF5.
    Eskola O; Grönroos TJ; Forsback S; Tuomela J; Komar G; Bergman J; Härkönen P; Haaparanta M; Minn H; Solin O
    Mol Imaging Biol; 2012 Apr; 14(2):205-12. PubMed ID: 21448777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients.
    Lin LL; Silvoniemi A; Stubbs JB; Rengan R; Suilamo S; Solin O; Divgi C; Eskola O; Sorger JM; Stabin MG; Kachur A; Hahn SM; Grönroos TJ; Forsback S; Evans SM; Koch CJ; Minn H
    Cancer Biother Radiopharm; 2012 Sep; 27(7):412-9. PubMed ID: 22897720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide].
    Evans SM; Joiner B; Jenkins WT; Laughlin KM; Lord EM; Koch CJ
    Br J Cancer; 1995 Oct; 72(4):875-82. PubMed ID: 7547234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors.
    Evans SM; Jenkins WT; Joiner B; Lord EM; Koch CJ
    Cancer Res; 1996 Jan; 56(2):405-11. PubMed ID: 8542599
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imaging of Tumor Hypoxia With 18F-EF5 PET/MRI in Cervical Cancer.
    Narva SI; Seppänen MP; Raiko JRH; Forsback SJ; Orte KJ; Virtanen JM; Hynninen J; Hietanen S
    Clin Nucl Med; 2021 Dec; 46(12):952-957. PubMed ID: 34619699
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Utility of 19F MRS detection of the hypoxic cell marker EF5 to assess cellular hypoxia in solid tumors.
    Salmon HW; Siemann DW
    Radiother Oncol; 2004 Dec; 73(3):359-66. PubMed ID: 15588883
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia.
    Bergeron M; Evans SM; Sharp FR; Koch CJ; Lord EM; Ferriero DM
    Neuroscience; 1999; 89(4):1357-66. PubMed ID: 10362320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.