BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

466 related articles for article (PubMed ID: 12565873)

  • 1. Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability.
    Morimoto M; Nishida T; Nagayama Y; Yasuda H
    Biochem Biophys Res Commun; 2003 Feb; 301(2):392-8. PubMed ID: 12565873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization.
    Wu K; Chen A; Pan ZQ
    J Biol Chem; 2000 Oct; 275(41):32317-24. PubMed ID: 10921923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.
    Wu K; Fuchs SY; Chen A; Tan P; Gomez C; Ronai Z; Pan ZQ
    Mol Cell Biol; 2000 Feb; 20(4):1382-93. PubMed ID: 10648623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
    Liu J; Furukawa M; Matsumoto T; Xiong Y
    Mol Cell; 2002 Dec; 10(6):1511-8. PubMed ID: 12504025
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
    Furukawa M; Zhang Y; McCarville J; Ohta T; Xiong Y
    Mol Cell Biol; 2000 Nov; 20(21):8185-97. PubMed ID: 11027288
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
    Kim AY; Bommeljé CC; Lee BE; Yonekawa Y; Choi L; Morris LG; Huang G; Kaufman A; Ryan RJ; Hao B; Ramanathan Y; Singh B
    J Biol Chem; 2008 Nov; 283(48):33211-20. PubMed ID: 18826954
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NEDD8 recruits E2-ubiquitin to SCF E3 ligase.
    Kawakami T; Chiba T; Suzuki T; Iwai K; Yamanaka K; Minato N; Suzuki H; Shimbara N; Hidaka Y; Osaka F; Omata M; Tanaka K
    EMBO J; 2001 Aug; 20(15):4003-12. PubMed ID: 11483504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G; Ganoth D; Hershko A
    Proc Natl Acad Sci U S A; 2006 Aug; 103(31):11515-20. PubMed ID: 16861300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.
    Chew EH; Poobalasingam T; Hawkey CJ; Hagen T
    Cell Signal; 2007 May; 19(5):1071-80. PubMed ID: 17254749
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts.
    Wirbelauer C; Sutterlüty H; Blondel M; Gstaiger M; Peter M; Reymond F; Krek W
    EMBO J; 2000 Oct; 19(20):5362-75. PubMed ID: 11032804
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.
    Dias DC; Dolios G; Wang R; Pan ZQ
    Proc Natl Acad Sci U S A; 2002 Dec; 99(26):16601-6. PubMed ID: 12481031
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TIP120A associates with unneddylated cullin 1 and regulates its neddylation.
    Hwang JW; Min KW; Tamura TA; Yoon JB
    FEBS Lett; 2003 Apr; 541(1-3):102-8. PubMed ID: 12706828
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
    Zheng N; Schulman BA; Song L; Miller JJ; Jeffrey PD; Wang P; Chu C; Koepp DM; Elledge SJ; Pagano M; Conaway RC; Conaway JW; Harper JW; Pavletich NP
    Nature; 2002 Apr; 416(6882):703-9. PubMed ID: 11961546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.
    Ohh M; Kim WY; Moslehi JJ; Chen Y; Chau V; Read MA; Kaelin WG
    EMBO Rep; 2002 Feb; 3(2):177-82. PubMed ID: 11818338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases.
    Goldenberg SJ; Cascio TC; Shumway SD; Garbutt KC; Liu J; Xiong Y; Zheng N
    Cell; 2004 Nov; 119(4):517-28. PubMed ID: 15537541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation.
    Chen A; Wu K; Fuchs SY; Tan P; Gomez C; Pan ZQ
    J Biol Chem; 2000 May; 275(20):15432-9. PubMed ID: 10748083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation- and Skp1-independent in vitro ubiquitination of E2F1 by multiple ROC-cullin ligases.
    Ohta T; Xiong Y
    Cancer Res; 2001 Feb; 61(4):1347-53. PubMed ID: 11245432
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle.
    Freed E; Lacey KR; Huie P; Lyapina SA; Deshaies RJ; Stearns T; Jackson PK
    Genes Dev; 1999 Sep; 13(17):2242-57. PubMed ID: 10485847
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.
    Zheng J; Yang X; Harrell JM; Ryzhikov S; Shim EH; Lykke-Andersen K; Wei N; Sun H; Kobayashi R; Zhang H
    Mol Cell; 2002 Dec; 10(6):1519-26. PubMed ID: 12504026
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.
    Emberley ED; Mosadeghi R; Deshaies RJ
    J Biol Chem; 2012 Aug; 287(35):29679-89. PubMed ID: 22767593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.