184 related articles for article (PubMed ID: 12568609)
1. Designing protein dimerizers: the importance of ligand conformational equilibria.
Carlson JC; Kanter A; Thuduppathy GR; Cody V; Pineda PE; McIvor RS; Wagner CR
J Am Chem Soc; 2003 Feb; 125(6):1501-7. PubMed ID: 12568609
[TBL] [Abstract][Full Text] [Related]
2. Towards understanding the mechanisms of molecular recognition by computer simulations of ligand-protein interactions.
Verkhivker GM; Rejto PA; Bouzida D; Arthurs S; Colson AB; Freer ST; Gehlhaar DK; Larson V; Luty BA; Marrone T; Rose PW
J Mol Recognit; 1999; 12(6):371-89. PubMed ID: 10611647
[TBL] [Abstract][Full Text] [Related]
3. Chemically induced dimerization of dihydrofolate reductase by a homobifunctional dimer of methotrexate.
Kopytek SJ; Standaert RF; Dyer JC; Hu JC
Chem Biol; 2000 May; 7(5):313-21. PubMed ID: 10801470
[TBL] [Abstract][Full Text] [Related]
4. Complementation between dimeric mutants as a probe of dimer-dimer interactions in tetrameric dihydrofolate reductase encoded by R67 plasmid of E. coli.
Dam J; Rose T; Goldberg ME; Blondel A
J Mol Biol; 2000 Sep; 302(1):235-50. PubMed ID: 10964572
[TBL] [Abstract][Full Text] [Related]
5. Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.
Cody V; Luft JR; Pangborn W
Acta Crystallogr D Biol Crystallogr; 2005 Feb; 61(Pt 2):147-55. PubMed ID: 15681865
[TBL] [Abstract][Full Text] [Related]
6. High-mannose-type glycan modifications of dihydrofolate reductase using glycan-methotrexate conjugates.
Totani K; Matsuo I; Ihara Y; Ito Y
Bioorg Med Chem; 2006 Aug; 14(15):5220-9. PubMed ID: 16647263
[TBL] [Abstract][Full Text] [Related]
7. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
Senkovich O; Schormann N; Chattopadhyay D
Acta Crystallogr D Biol Crystallogr; 2009 Jul; 65(Pt 7):704-16. PubMed ID: 19564691
[TBL] [Abstract][Full Text] [Related]
8. Incorporating dynamics in E. coli dihydrofolate reductase enhances structure-based drug discovery.
Lerner MG; Bowman AL; Carlson HA
J Chem Inf Model; 2007; 47(6):2358-65. PubMed ID: 17877338
[TBL] [Abstract][Full Text] [Related]
9. Conformational analysis of the lipophilic antifolate trimetrexate.
Hoffman VA; Welsh WJ
Cancer Biochem Biophys; 1995 Jan; 14(4):281-95. PubMed ID: 7767902
[TBL] [Abstract][Full Text] [Related]
10. Cyclophilin-promoted folding of mouse dihydrofolate reductase does not include the slow conversion of the late-folding intermediate to the active enzyme.
von Ahsen O; Lim JH; Caspers P; Martin F; Schönfeld HJ; Rassow J; Pfanner N
J Mol Biol; 2000 Mar; 297(3):809-18. PubMed ID: 10731431
[TBL] [Abstract][Full Text] [Related]
11. Neutron diffraction studies of Escherichia coli dihydrofolate reductase complexed with methotrexate.
Bennett B; Langan P; Coates L; Mustyakimov M; Schoenborn B; Howell EE; Dealwis C
Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18493-8. PubMed ID: 17130456
[TBL] [Abstract][Full Text] [Related]
12. Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.
Hicks SN; Smiley RD; Hamilton JB; Howell EE
Biochemistry; 2003 Sep; 42(36):10569-78. PubMed ID: 12962480
[TBL] [Abstract][Full Text] [Related]
13. Theory and normal-mode analysis of change in protein vibrational dynamics on ligand binding.
Moritsugu K; Njunda BM; Smith JC
J Phys Chem B; 2010 Jan; 114(3):1479-85. PubMed ID: 20043649
[TBL] [Abstract][Full Text] [Related]
14. Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry.
Cammarata MB; Thyer R; Rosenberg J; Ellington A; Brodbelt JS
J Am Chem Soc; 2015 Jul; 137(28):9128-35. PubMed ID: 26125523
[TBL] [Abstract][Full Text] [Related]
15. NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase.
Johnson JM; Meiering EM; Wright JE; Pardo J; Rosowsky A; Wagner G
Biochemistry; 1997 Apr; 36(15):4399-411. PubMed ID: 9109647
[TBL] [Abstract][Full Text] [Related]
16. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region.
Summerfield RL; Daigle DM; Mayer S; Mallik D; Hughes DW; Jackson SG; Sulek M; Organ MG; Brown ED; Junop MS
J Med Chem; 2006 Nov; 49(24):6977-86. PubMed ID: 17125251
[TBL] [Abstract][Full Text] [Related]
17. Chemically controlled self-assembly of protein nanorings.
Carlson JC; Jena SS; Flenniken M; Chou TF; Siegel RA; Wagner CR
J Am Chem Soc; 2006 Jun; 128(23):7630-8. PubMed ID: 16756320
[TBL] [Abstract][Full Text] [Related]
18. Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima.
Maglia G; Javed MH; Allemann RK
Biochem J; 2003 Sep; 374(Pt 2):529-35. PubMed ID: 12765545
[TBL] [Abstract][Full Text] [Related]
19. The coordination of the isomerization of a conserved non-prolyl cis peptide bond with the rate-limiting steps in the folding of dihydrofolate reductase.
Svensson AK; O'Neill JC; Matthews CR
J Mol Biol; 2003 Feb; 326(2):569-83. PubMed ID: 12559923
[TBL] [Abstract][Full Text] [Related]
20. Ligand binding to a high-energy partially unfolded protein.
Kasper JR; Park C
Protein Sci; 2015 Jan; 24(1):129-37. PubMed ID: 25367157
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
