196 related articles for article (PubMed ID: 12569552)
1. Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Suzuki M; Kobayashi H; Tanaka Y; Hirashima Y; Kanayama N; Takei Y; Saga Y; Suzuki M; Itoh H; Terao T
Int J Cancer; 2003 Apr; 104(3):289-302. PubMed ID: 12569552
[TBL] [Abstract][Full Text] [Related]
2. Suppression of urokinase expression and tumor metastasis by bikunin overexpression [mini-review].
Kobayashi H
Hum Cell; 2001 Sep; 14(3):233-6. PubMed ID: 11774742
[TBL] [Abstract][Full Text] [Related]
3. Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis.
Tanaka Y; Kobayashi H; Suzuki M; Hirashima Y; Kanayama N; Terao T
Int J Cancer; 2004 Apr; 109(3):336-47. PubMed ID: 14961570
[TBL] [Abstract][Full Text] [Related]
4. Transforming growth factor-beta1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells.
Hirashima Y; Kobayashi H; Suzuki M; Tanaka Y; Kanayama N; Terao T
J Biol Chem; 2003 Jul; 278(29):26793-802. PubMed ID: 12743121
[TBL] [Abstract][Full Text] [Related]
5. Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade.
Kobayashi H; Suzuki M; Kanayama N; Nishida T; Takigawa M; Terao T
Eur J Biochem; 2002 Aug; 269(16):3945-57. PubMed ID: 12180971
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro.
Takei Y; Mizukami H; Saga Y; Kobayashi H; Suzuki M; Matsushita T; Ozawa K; Suzuki M
Int J Cancer; 2005 Jan; 113(1):54-8. PubMed ID: 15386422
[TBL] [Abstract][Full Text] [Related]
7. Genetic down-regulation of phosphoinositide 3-kinase by bikunin correlates with suppression of invasion and metastasis in human ovarian cancer HRA cells.
Kobayashi H; Suzuki M; Kanayama N; Terao T
J Biol Chem; 2004 Feb; 279(8):6371-9. PubMed ID: 14597629
[TBL] [Abstract][Full Text] [Related]
8. A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Kobayashi H; Suzuki M; Kanayama N; Terao T
Clin Exp Metastasis; 2004; 21(2):159-66. PubMed ID: 15168733
[TBL] [Abstract][Full Text] [Related]
9. A kunitz-type protease inhibitor bikunin disrupts ligand-induced oligomerization of receptors for transforming growth factor (TGF)-beta and subsequently suppresses TGF-beta signalings.
Yagyu T; Kobayashi H; Wakahara K; Matsuzaki H; Kondo T; Kurita N; Sekino H; Inagaki K; Suzuki M; Kanayama N; Terao T
FEBS Lett; 2004 Oct; 576(3):408-16. PubMed ID: 15498571
[TBL] [Abstract][Full Text] [Related]
10. A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
Kobayashi H; Suzuki M; Tanaka Y; Kanayama N; Terao T
J Biol Chem; 2003 Mar; 278(10):7790-9. PubMed ID: 12496270
[TBL] [Abstract][Full Text] [Related]
11. Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Kobayashi H; Fukuda Y; Yoshida R; Kanada Y; Nishiyama S; Suzuki M; Kanayama N; Terao T
Int J Cancer; 2004 Nov; 112(3):519-24. PubMed ID: 15382080
[TBL] [Abstract][Full Text] [Related]
12. Enhanced spontaneous metastasis in bikunin-deficient mice.
Yagyu T; Kobayashi H; Matsuzaki H; Wakahara K; Kondo T; Kurita N; Sekino H; Inagaki K
Int J Cancer; 2006 May; 118(9):2322-8. PubMed ID: 16331631
[TBL] [Abstract][Full Text] [Related]
13. Reduced syndecan-1 expression stimulates heparin-binding growth factor-mediated invasion in ovarian cancer cells in a urokinase-independent mechanism.
Matsuzaki H; Kobayashi H; Yagyu T; Wakahara K; Kondo T; Kurita N; Sekino H; Inagaki K; Suzuki M; Kanayama N; Terao T
Oncol Rep; 2005 Aug; 14(2):449-57. PubMed ID: 16012729
[TBL] [Abstract][Full Text] [Related]
14. Calcitonin inhibits invasion of breast cancer cells: involvement of urokinase-type plasminogen activator (uPA) and uPA receptor.
Han B; Nakamura M; Zhou G; Ishii A; Nakamura A; Bai Y; Mori I; Kakudo K
Int J Oncol; 2006 Apr; 28(4):807-14. PubMed ID: 16525628
[TBL] [Abstract][Full Text] [Related]
15. A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
Kobayashi H; Sugino D; She MY; Ohi H; Hirashima Y; Shinohara H; Fujie M; Shibata K; Terao T
Eur J Biochem; 1998 May; 253(3):817-26. PubMed ID: 9654084
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.
Suzuki M; Kobayashi H; Kanayama N; Saga Y; Suzuki M; Lin CY; Dickson RB; Terao T
J Biol Chem; 2004 Apr; 279(15):14899-908. PubMed ID: 14747469
[TBL] [Abstract][Full Text] [Related]
17. Bikunin target genes in ovarian cancer cells identified by microarray analysis.
Suzuki M; Kobayashi H; Tanaka Y; Hirashima Y; Kanayama N; Takei Y; Saga Y; Suzuki M; Itoh H; Terao T
J Biol Chem; 2003 Apr; 278(17):14640-6. PubMed ID: 12571229
[TBL] [Abstract][Full Text] [Related]
18. Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: implication for anti-invasive role of HAI-2/PB in glioblastoma cells.
Hamasuna R; Kataoka H; Meng JY; Itoh H; Moriyama T; Wakisaka S; Koono M
Int J Cancer; 2001 Aug; 93(3):339-45. PubMed ID: 11433397
[TBL] [Abstract][Full Text] [Related]
19. Kunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells.
Suzuki M; Kobayashi H; Fujie M; Nishida T; Takigawa M; Kanayama N; Terao T
J Biol Chem; 2002 Mar; 277(10):8022-32. PubMed ID: 11777908
[TBL] [Abstract][Full Text] [Related]
20. Bikunin plus paclitaxel markedly reduces tumor burden and ascites in mouse model of ovarian cancer.
Kobayashi H; Yagyu T; Inagaki K; Kondo T; Suzuki M; Kanayama N; Terao T
Int J Cancer; 2004 May; 110(1):134-9. PubMed ID: 15054878
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
