545 related articles for article (PubMed ID: 12571232)
1. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
[TBL] [Abstract][Full Text] [Related]
2. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
[TBL] [Abstract][Full Text] [Related]
3. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
[TBL] [Abstract][Full Text] [Related]
4. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
5. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
6. The role of constitutive androstane receptor in oxazaphosphorine-mediated induction of drug-metabolizing enzymes in human hepatocytes.
Wang D; Li L; Fuhrman J; Ferguson S; Wang H
Pharm Res; 2011 Aug; 28(8):2034-44. PubMed ID: 21487929
[TBL] [Abstract][Full Text] [Related]
7. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
[TBL] [Abstract][Full Text] [Related]
8. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
[TBL] [Abstract][Full Text] [Related]
9. Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors.
Mäkinen J; Frank C; Jyrkkärinne J; Gynther J; Carlberg C; Honkakoski P
Mol Pharmacol; 2002 Aug; 62(2):366-78. PubMed ID: 12130690
[TBL] [Abstract][Full Text] [Related]
10. Synergistically enhanced CYP2B6 inducibility between a polymorphic mutation in CYP2B6 promoter and pregnane X receptor activation.
Li H; Ferguson SS; Wang H
Mol Pharmacol; 2010 Oct; 78(4):704-13. PubMed ID: 20624854
[TBL] [Abstract][Full Text] [Related]
11. Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics.
Inoue K; Borchers CH; Negishi M
Biochem J; 2006 Aug; 398(1):125-33. PubMed ID: 16623664
[TBL] [Abstract][Full Text] [Related]
12. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
13. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
14. AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.
Rencurel F; Stenhouse A; Hawley SA; Friedberg T; Hardie DG; Sutherland C; Wolf CR
J Biol Chem; 2005 Feb; 280(6):4367-73. PubMed ID: 15572372
[TBL] [Abstract][Full Text] [Related]
15. Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells.
Swales K; Kakizaki S; Yamamoto Y; Inoue K; Kobayashi K; Negishi M
J Biol Chem; 2005 Feb; 280(5):3458-66. PubMed ID: 15563456
[TBL] [Abstract][Full Text] [Related]
16. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.
Li L; Hassan HE; Tolson AH; Ferguson SS; Eddington ND; Wang H
J Pharmacol Exp Ther; 2010 Dec; 335(3):562-71. PubMed ID: 20829393
[TBL] [Abstract][Full Text] [Related]
17. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors.
Wang H; Negishi M
Curr Drug Metab; 2003 Dec; 4(6):515-25. PubMed ID: 14683479
[TBL] [Abstract][Full Text] [Related]
19. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
[TBL] [Abstract][Full Text] [Related]
20. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
