These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

2350 related articles for article (PubMed ID: 12576463)

  • 1. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
    Park MT; Kang JA; Choi JA; Kang CM; Kim TH; Bae S; Kang S; Kim S; Choi WI; Cho CK; Chung HY; Lee YS; Lee SJ
    Clin Cancer Res; 2003 Feb; 9(2):878-85. PubMed ID: 12576463
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM; Choi YJ; Han Y; Yun YS; Hong SH
    Toxicol Appl Pharmacol; 2009 Aug; 239(1):87-97. PubMed ID: 19481559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.
    Huisman C; Ferreira CG; Bröker LE; Rodriguez JA; Smit EF; Postmus PE; Kruyt FA; Giaccone G
    Clin Cancer Res; 2002 Feb; 8(2):596-606. PubMed ID: 11839682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW; Chong SY; Kim JY; Eom JI; Jeung HK; Maeng HY; Lee ST; Min YH
    Clin Cancer Res; 2003 Oct; 9(13):5018-27. PubMed ID: 14581377
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A; Gillissen B; Müller A; Normand G; Hemmati PG; Schuler M; Dörken B; Daniel PT
    Oncogene; 2004 Jun; 23(26):4523-35. PubMed ID: 15064710
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH; Lee BH; Lim SC
    Biochem Pharmacol; 2004 Nov; 68(9):1845-55. PubMed ID: 15450950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H; Bhalla K; Wang HG
    Cancer Res; 2003 Apr; 63(7):1483-9. PubMed ID: 12670894
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
    Perchellet EM; Wang Y; Weber RL; Sperfslage BJ; Lou K; Crossland J; Hua DH; Perchellet JP
    Biochem Pharmacol; 2004 Feb; 67(3):523-37. PubMed ID: 15037204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis.
    Gao CF; Ren S; Zhang L; Nakajima T; Ichinose S; Hara T; Koike K; Tsuchida N
    Exp Cell Res; 2001 Apr; 265(1):145-51. PubMed ID: 11281652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.
    Yu W; Sanders BG; Kline K
    Cancer Res; 2003 May; 63(10):2483-91. PubMed ID: 12750270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ; Ng LT; Lin CC
    Eur J Pharmacol; 2005 Aug; 518(2-3):96-106. PubMed ID: 16054126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
    von Haefen C; Wieder T; Gillissen B; Stärck L; Graupner V; Dörken B; Daniel PT
    Oncogene; 2002 Jun; 21(25):4009-19. PubMed ID: 12037683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines.
    Henkels KM; Turchi JJ
    Cancer Res; 1999 Jul; 59(13):3077-83. PubMed ID: 10397248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ponicidin, an ent-kaurane diterpenoid derived from a constituent of the herbal supplement PC-SPES, Rabdosia rubescens, induces apoptosis by activation of caspase-3 and mitochondrial events in lung cancer cells in vitro.
    Liu JJ; Huang RW; Lin DJ; Peng J; Zhang M; Pan X; Hou M; Wu XY; Lin Q; Chen F
    Cancer Invest; 2006 Mar; 24(2):136-48. PubMed ID: 16537182
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of distinct consecutive phases in non-genotoxic p53-induced apoptosis of Ewing tumor cells and the rate-limiting role of caspase 8.
    Kovar H; Jug G; Printz D; Bartl S; Schmid G; Wesierska-Gadek J
    Oncogene; 2000 Aug; 19(36):4096-107. PubMed ID: 10962570
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bax membrane insertion during Fas(CD95)-induced apoptosis precedes cytochrome c release and is inhibited by Bcl-2.
    Murphy KM; Streips UN; Lock RB
    Oncogene; 1999 Oct; 18(44):5991-9. PubMed ID: 10557088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.
    Sawada M; Nakashima S; Banno Y; Yamakawa H; Hayashi K; Takenaka K; Nishimura Y; Sakai N; Nozawa Y
    Cell Death Differ; 2000 Sep; 7(9):761-72. PubMed ID: 11042671
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species.
    Pan MH; Lai CS; Hsu PC; Wang YJ
    J Agric Food Chem; 2005 Feb; 53(3):620-30. PubMed ID: 15686411
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism.
    Shibata MA; Ito Y; Morimoto J; Otsuki Y
    Carcinogenesis; 2004 Oct; 25(10):1887-98. PubMed ID: 15180944
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5.
    Choi SY; Kim MJ; Chung HY; Lee SJ; Jang YJ
    Oncol Rep; 2007 Jan; 17(1):175-84. PubMed ID: 17143496
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 118.