124 related articles for article (PubMed ID: 12578370)
1. Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies.
Blaszczyk J; Li Y; Shi G; Yan H; Ji X
Biochemistry; 2003 Feb; 42(6):1573-80. PubMed ID: 12578370
[TBL] [Abstract][Full Text] [Related]
2. Catalytic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: site-directed mutagenesis and biochemical studies.
Li Y; Wu Y; Blaszczyk J; Ji X; Yan H
Biochemistry; 2003 Feb; 42(6):1581-8. PubMed ID: 12578371
[TBL] [Abstract][Full Text] [Related]
3. Essential roles of a dynamic loop in the catalysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Blaszczyk J; Li Y; Wu Y; Shi G; Ji X; Yan H
Biochemistry; 2004 Feb; 43(6):1469-77. PubMed ID: 14769023
[TBL] [Abstract][Full Text] [Related]
4. Is the critical role of loop 3 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase in catalysis due to loop-3 residues arginine-84 and tryptophan-89? Site-directed mutagenesis, biochemical, and crystallographic studies.
Li Y; Blaszczyk J; Wu Y; Shi G; Ji X; Yan H
Biochemistry; 2005 Jun; 44(24):8590-9. PubMed ID: 15952765
[TBL] [Abstract][Full Text] [Related]
5. Dynamics of the conformational transitions in the assembling of the Michaelis complex of a bisubstrate enzyme: a (15)N relaxation study of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Lescop E; Lu Z; Liu Q; Xu H; Li G; Xia B; Yan H; Jin C
Biochemistry; 2009 Jan; 48(2):302-12. PubMed ID: 19108643
[TBL] [Abstract][Full Text] [Related]
6. An enhanced molecular dynamics study of HPPK-ATP conformation space exploration and ATP binding to HPPK.
Su L; Cukier RI
J Phys Chem A; 2009 Mar; 113(10):2025-35. PubMed ID: 19191740
[TBL] [Abstract][Full Text] [Related]
7. Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Blaszczyk J; Shi G; Li Y; Yan H; Ji X
Structure; 2004 Mar; 12(3):467-75. PubMed ID: 15016362
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of the conformational transitions in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by NMR spectroscopy.
Li G; Felczak K; Shi G; Yan H
Biochemistry; 2006 Oct; 45(41):12573-81. PubMed ID: 17029412
[TBL] [Abstract][Full Text] [Related]
9. Kinetic and structural characterization of a product complex of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.
Garçon A; Bermingham A; Lian LY; Derrick JP
Biochem J; 2004 Jun; 380(Pt 3):867-73. PubMed ID: 15018613
[TBL] [Abstract][Full Text] [Related]
10. The structure and mechanism of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Derrick JP
Vitam Horm; 2008; 79():411-33. PubMed ID: 18804704
[TBL] [Abstract][Full Text] [Related]
11. Hamiltonian replica exchange method study of Escherichia coli and Yersinia pestis HPPK.
Su L; Cukier RI
J Phys Chem B; 2009 Dec; 113(50):16197-208. PubMed ID: 19924845
[TBL] [Abstract][Full Text] [Related]
12. Structure and dynamics of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Yan H; Blaszczyk J; Xiao B; Shi G; Ji X
J Mol Graph Model; 2001; 19(1):70-7. PubMed ID: 11381532
[TBL] [Abstract][Full Text] [Related]
13. Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.
Blaszczyk J; Li Y; Cherry S; Alexandratos J; Wu Y; Shaw G; Tropea JE; Waugh DS; Yan H; Ji X
Acta Crystallogr D Biol Crystallogr; 2007 Nov; 63(Pt 11):1169-77. PubMed ID: 18007032
[TBL] [Abstract][Full Text] [Related]
14. Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution.
Blaszczyk J; Shi G; Yan H; Ji X
Structure; 2000 Oct; 8(10):1049-58. PubMed ID: 11080626
[TBL] [Abstract][Full Text] [Related]
15. The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae.
Hennig M; Dale GE; D'arcy A; Danel F; Fischer S; Gray CP; Jolidon S; Müller F; Page MG; Pattison P; Oefner C
J Mol Biol; 1999 Mar; 287(2):211-9. PubMed ID: 10080886
[TBL] [Abstract][Full Text] [Related]
16. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Sandmark J; Eliot AC; Famm K; Schneider G; Kirsch JF
Biochemistry; 2004 Feb; 43(5):1213-22. PubMed ID: 14756557
[TBL] [Abstract][Full Text] [Related]
17. Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.
Dennis ML; Chhabra S; Wang ZC; Debono A; Dolezal O; Newman J; Pitcher NP; Rahmani R; Cleary B; Barlow N; Hattarki M; Graham B; Peat TS; Baell JB; Swarbrick JD
J Med Chem; 2014 Nov; 57(22):9612-26. PubMed ID: 25357262
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of the bifunctional dihydroneopterin aldolase/6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Streptococcus pneumoniae.
Garçon A; Levy C; Derrick JP
J Mol Biol; 2006 Jul; 360(3):644-53. PubMed ID: 16781731
[TBL] [Abstract][Full Text] [Related]
19. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies.
Shi G; Blaszczyk J; Ji X; Yan H
J Med Chem; 2001 Apr; 44(9):1364-71. PubMed ID: 11311059
[TBL] [Abstract][Full Text] [Related]
20. Molecular motions and conformational changes of HPPK.
Keskin O; Ji X; Blaszcyk J; Covell DG
Proteins; 2002 Nov; 49(2):191-205. PubMed ID: 12211000
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
