143 related articles for article (PubMed ID: 12585893)
1. Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue.
Bunch L; Liljefors T; Greenwood JR; Frydenvang K; Bräuner-Osborne H; Krogsgaard-Larsen P; Madsen U
J Org Chem; 2003 Feb; 68(4):1489-95. PubMed ID: 12585893
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.
Brehm L; Greenwood JR; Sløk FA; Holm MM; Nielsen B; Geneser U; Stensbøl TB; Bräuner-Osborne H; Begtrup M; Egebjerg J; Krogsgaard-Larsen P
Chirality; 2004 Aug; 16(7):452-66. PubMed ID: 15236343
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors--focus on subtypes iGlu(5-7).
Bunch L; Gefflaut T; Alaux S; Sagot E; Nielsen B; Pickering DS
Eur J Pharmacol; 2009 May; 609(1-3):1-4. PubMed ID: 19285062
[TBL] [Abstract][Full Text] [Related]
4. Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.
Sagot E; Pickering DS; Pu X; Umberti M; Stensbøl TB; Nielsen B; Chapelet M; Bolte J; Gefflaut T; Bunch L
J Med Chem; 2008 Jul; 51(14):4093-103. PubMed ID: 18578478
[TBL] [Abstract][Full Text] [Related]
5. Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3.
Bunch L; Nielsen B; Jensen AA; Bräuner-Osborne H
J Med Chem; 2006 Jan; 49(1):172-8. PubMed ID: 16392801
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid.
Conti P; Caligiuri A; Pinto A; Roda G; Tamborini L; Nielsen B; Madsen U; Frydenvang K; Colombo A; De Micheli C
Eur J Med Chem; 2007 Aug; 42(8):1059-68. PubMed ID: 17346858
[TBL] [Abstract][Full Text] [Related]
7. Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors.
Johansen TN; Greenwood JR; Frydenvang K; Madsen U; Krogsgaard-Larsen P
Chirality; 2003 Feb; 15(2):167-79. PubMed ID: 12520509
[TBL] [Abstract][Full Text] [Related]
8. Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology.
Frølund B; Greenwood JR; Holm MM; Egebjerg J; Madsen U; Nielsen B; Bräuner-Osborne H; Stensbøl TB; Krogsgaard-Larsen P
Bioorg Med Chem; 2005 Sep; 13(18):5391-8. PubMed ID: 16043357
[TBL] [Abstract][Full Text] [Related]
9. Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.
Johansen TN; Stensbøl TB; Nielsen B; Vogensen SB; Frydenvang K; Sløk FA; Bräüner-Osborne H; Madsen U; Krogsgaard-Larsen P
Chirality; 2001; 13(9):523-32. PubMed ID: 11579444
[TBL] [Abstract][Full Text] [Related]
10. The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Clausen RP; Hansen KB; Calí P; Nielsen B; Greenwood JR; Begtrup M; Egebjerg J; Bräuner-Osborne H
Eur J Pharmacol; 2004 Sep; 499(1-2):35-44. PubMed ID: 15363949
[TBL] [Abstract][Full Text] [Related]
11. Rational design, synthesis and pharmacological evaluation of the (2R)- and (2S)-stereoisomers of 3-(2-carboxypyrrolidinyl)-2-methyl acetic acid as ligands for the ionotropic glutamate receptors.
Rasmussen JL; Storgaard M; Pickering DS; Bunch L
ChemMedChem; 2011 Mar; 6(3):498-504. PubMed ID: 21268287
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors.
Conti P; di Ventimiglia SJ; Pinto A; Tamborini L; Menniti FS; Lazzaro JT; De Micheli C
Chem Biodivers; 2008 Apr; 5(4):657-63. PubMed ID: 18421758
[TBL] [Abstract][Full Text] [Related]
13. Rigid nonproteinogenic cyclic amino acids as ligands for glutamate receptors: trans-tris(homoglutamic) acids.
Meyer U; Bisel P; Bräuner-Osborne H; Madsen U; Höfner G; Wanner KT; Frahm AW
Chirality; 2005 Feb; 17(2):99-107. PubMed ID: 15660439
[TBL] [Abstract][Full Text] [Related]
14. Enantioselective total synthesis of (1R,3S,4R,5R)-1-amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic acid. A full-aldol access to carbaketose derivatives.
Battistini L; Curti C; Zanardi F; Rassu G; Auzzas L; Casiraghi G
J Org Chem; 2004 Apr; 69(7):2611-3. PubMed ID: 15049672
[TBL] [Abstract][Full Text] [Related]
15. Aminobicyclo[2.2.1.]heptane dicarboxylic acids (ABHD), rigid analogs of ACPD and glutamic acid: synthesis and pharmacological activity on metabotropic receptors mGluR1 and mGluR2.
Tellier F; Acher F; Brabet I; Pin JP; Azerad R
Bioorg Med Chem; 1998 Feb; 6(2):195-208. PubMed ID: 9547943
[TBL] [Abstract][Full Text] [Related]
16. Spiro[2.2]pentane as a dissymmetric scaffold for conformationally constrained analogues of glutamic acid: focus on racemic 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids.
Pellicciari R; Marinozzi M; Camaioni E; del Carmen Nùnez M; Costantino G; Gasparini F; Giorgi G; Macchiarulo A; Subramanian N
J Org Chem; 2002 Aug; 67(16):5497-507. PubMed ID: 12153247
[TBL] [Abstract][Full Text] [Related]
17. Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology.
Stensbøl TB; Uhlmann P; Morel S; Eriksen BL; Felding J; Kromann H; Hermit MB; Greenwood JR; Braüner-Osborne H; Madsen U; Junager F; Krogsgaard-Larsen P; Begtrup M; Vedsø P
J Med Chem; 2002 Jan; 45(1):19-31. PubMed ID: 11754576
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids.
Conti P; De Amici M; Joppolo Di Ventimiglia S; Stensbøl TB; Madsen U; Bräuner-Osborne H; Russo E; De Sarro G; Bruno G; De Micheli C
J Med Chem; 2003 Jul; 46(14):3102-8. PubMed ID: 12825948
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and nicotinic binding studies on enantiopure pinnamine variants with an 8-azabicyclo[3.2.1]octane moiety.
Schwarz S; Kämpchen T; Tilotta MC; Gündisch D; Seitz G
Pharmazie; 2003 May; 58(5):295-9. PubMed ID: 12779043
[TBL] [Abstract][Full Text] [Related]
20. Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA.
Jensen AA; Christesen T; Bølcho U; Greenwood JR; Postorino G; Vogensen SB; Johansen TN; Egebjerg J; Bräuner-Osborne H; Clausen RP
J Med Chem; 2007 Aug; 50(17):4177-85. PubMed ID: 17672447
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]