BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 12586360)

  • 1. Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation.
    Haendeler J; Hoffmann J; Rahman S; Zeiher AM; Dimmeler S
    FEBS Lett; 2003 Feb; 536(1-3):180-6. PubMed ID: 12586360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of HSP90-dependent telomerase activity in amyloid β-induced apoptosis of cerebral endothelial cells.
    Chiu WT; Shen SC; Yang LY; Chow JM; Wu CY; Chen YC
    J Cell Physiol; 2011 Aug; 226(8):2041-51. PubMed ID: 21520056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation.
    Yun BG; Matts RL
    Cell Signal; 2005 Dec; 17(12):1477-85. PubMed ID: 15935620
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
    Fujiwara H; Yamakuni T; Ueno M; Ishizuka M; Shinkawa T; Isobe T; Ohizumi Y
    J Pharmacol Exp Ther; 2004 Sep; 310(3):1288-95. PubMed ID: 15161934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.
    Liu W; Akhand AA; Takeda K; Kawamoto Y; Itoigawa M; Kato M; Suzuki H; Ishikawa N; Nakashima I
    Cell Death Differ; 2003 Jul; 10(7):772-81. PubMed ID: 12815460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.
    Kawauchi K; Ihjima K; Yamada O
    J Immunol; 2005 May; 174(9):5261-9. PubMed ID: 15843522
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of Oryza sativa telomerase reverse transcriptase and possible role of its phosphorylation in the control of telomerase activity.
    Oguchi K; Tamura K; Takahashi H
    Gene; 2004 Nov; 342(1):57-66. PubMed ID: 15527966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of Akt kinase activity by binding to Hsp90.
    Sato S; Fujita N; Tsuruo T
    Proc Natl Acad Sci U S A; 2000 Sep; 97(20):10832-7. PubMed ID: 10995457
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis.
    Zhang R; Luo D; Miao R; Bai L; Ge Q; Sessa WC; Min W
    Oncogene; 2005 Jun; 24(24):3954-63. PubMed ID: 15782121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down-regulation of telomerase activity via protein phosphatase 2A activation in salvicine-induced human leukemia HL-60 cell apoptosis.
    Liu WJ; Jiang JF; Xiao D; Ding J
    Biochem Pharmacol; 2002 Dec; 64(12):1677-87. PubMed ID: 12445857
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.
    Xu W; Yuan X; Jung YJ; Yang Y; Basso A; Rosen N; Chung EJ; Trepel J; Neckers L
    Cancer Res; 2003 Nov; 63(22):7777-84. PubMed ID: 14633703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
    Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate.
    Cazzolli R; Carpenter L; Biden TJ; Schmitz-Peiffer C
    Diabetes; 2001 Oct; 50(10):2210-8. PubMed ID: 11574400
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
    Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Both estrogen and raloxifene protect against beta-amyloid-induced neurotoxicity in estrogen receptor alpha-transfected PC12 cells by activation of telomerase activity via Akt cascade.
    Du B; Ohmichi M; Takahashi K; Kawagoe J; Ohshima C; Igarashi H; Mori-Abe A; Saitoh M; Ohta T; Ohishi A; Doshida M; Tezuka N; Takahashi T; Kurachi H
    J Endocrinol; 2004 Dec; 183(3):605-15. PubMed ID: 15590986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT; Conrad DM; Hoskin DW
    Cell Signal; 2007 Jan; 19(1):139-51. PubMed ID: 16844342
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HSP90 and Akt modulate Ang-1-induced angiogenesis via NO in coronary artery endothelium.
    Chen JX; Lawrence ML; Cunningham G; Christman BW; Meyrick B
    J Appl Physiol (1985); 2004 Feb; 96(2):612-20. PubMed ID: 14555685
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Up-regulation of the association between heat shock protein 90 and endothelial nitric oxide synthase prevents high glucose-induced apoptosis in human endothelial cells.
    Lin LY; Lin CY; Ho FM; Liau CS
    J Cell Biochem; 2005 Jan; 94(1):194-201. PubMed ID: 15526284
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells.
    Di Maira G; Brustolon F; Pinna LA; Ruzzene M
    Cell Mol Life Sci; 2009 Oct; 66(20):3363-73. PubMed ID: 19662498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.
    Kupatt C; Dessy C; Hinkel R; Raake P; Daneau G; Bouzin C; Boekstegers P; Feron O
    Arterioscler Thromb Vasc Biol; 2004 Aug; 24(8):1435-41. PubMed ID: 15178564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.