BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 12586772)

  • 1. Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes.
    Kanoh Y; Sajan MP; Bandyopadhyay G; Miura A; Standaert ML; Farese RV
    Endocrinology; 2003 Mar; 144(3):947-54. PubMed ID: 12586772
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.
    Beeson M; Sajan MP; Dizon M; Grebenev D; Gomez-Daspet J; Miura A; Kanoh Y; Powe J; Bandyopadhyay G; Standaert ML; Farese RV
    Diabetes; 2003 Aug; 52(8):1926-34. PubMed ID: 12882907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota.
    Standaert ML; Ortmeyer HK; Sajan MP; Kanoh Y; Bandyopadhyay G; Hansen BC; Farese RV
    Diabetes; 2002 Oct; 51(10):2936-43. PubMed ID: 12351430
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats.
    Kanoh Y; Bandyopadhyay G; Sajan MP; Standaert ML; Farese RV
    Endocrinology; 2001 Apr; 142(4):1595-605. PubMed ID: 11250941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.
    Herr HJ; Bernard JR; Reeder DW; Rivas DA; Limon JJ; Yaspelkis BB
    J Physiol; 2005 Jun; 565(Pt 2):627-36. PubMed ID: 15802290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects.
    Luna V; Casauban L; Sajan MP; Gomez-Daspet J; Powe JL; Miura A; Rivas J; Standaert ML; Farese RV
    Diabetologia; 2006 Feb; 49(2):375-82. PubMed ID: 16395615
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.
    Tremblay F; Lavigne C; Jacques H; Marette A
    Diabetes; 2001 Aug; 50(8):1901-10. PubMed ID: 11473054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects.
    Sajan MP; Standaert ML; Miura A; Bandyopadhyay G; Vollenweider P; Franklin DM; Lea-Currie R; Farese RV
    J Clin Endocrinol Metab; 2004 Aug; 89(8):3994-8. PubMed ID: 15292339
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.
    Kim YB; Kotani K; Ciaraldi TP; Henry RR; Kahn BB
    Diabetes; 2003 Aug; 52(8):1935-42. PubMed ID: 12882908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats.
    Tremblay F; Lavigne C; Jacques H; Marette A
    Diabetes; 2003 Jan; 52(1):29-37. PubMed ID: 12502490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin and PIP3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites.
    Standaert ML; Bandyopadhyay G; Kanoh Y; Sajan MP; Farese RV
    Biochemistry; 2001 Jan; 40(1):249-55. PubMed ID: 11141077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.
    Standaert ML; Sajan MP; Miura A; Kanoh Y; Chen HC; Farese RV; Farese RV
    J Biol Chem; 2004 Jun; 279(24):24929-34. PubMed ID: 15069067
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle.
    Temofonte N; Sajan MP; Nimal S; Pastoor T; Fumero C; Casaubon L; Powe JL; Standaert ML; Farese RV
    Diabetologia; 2009 Jan; 52(1):60-4. PubMed ID: 18972094
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
    Miura A; Sajan MP; Standaert ML; Bandyopadhyay G; Kahn CR; Farese RV
    Biochemistry; 2004 Dec; 43(49):15503-9. PubMed ID: 15581362
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta.
    Bandyopadhyay G; Standaert ML; Sajan MP; Karnitz LM; Cong L; Quon MJ; Farese RV
    Mol Endocrinol; 1999 Oct; 13(10):1766-72. PubMed ID: 10517677
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.
    Steiler TL; Galuska D; Leng Y; Chibalin AV; Gilbert M; Zierath JR
    Endocrinology; 2003 Dec; 144(12):5259-67. PubMed ID: 12960081
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Atypical protein kinase C in insulin action and insulin resistance.
    Farese RV; Sajan MP; Standaert ML
    Biochem Soc Trans; 2005 Apr; 33(Pt 2):350-3. PubMed ID: 15787604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular depletion of atypical PKC{lambda} is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells.
    Stretton C; Evans A; Hundal HS
    Am J Physiol Endocrinol Metab; 2010 Sep; 299(3):E402-12. PubMed ID: 20530734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes.
    Farese RV; Sajan MP; Standaert ML
    Exp Biol Med (Maywood); 2005 Oct; 230(9):593-605. PubMed ID: 16179727
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport.
    Singh MK; Krisan AD; Crain AM; Collins DE; Yaspelkis BB
    Metabolism; 2003 Sep; 52(9):1196-205. PubMed ID: 14506627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.