These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. A phase II multicenter, randomized, double-blind, safety trial assessing the pharmacokinetics, pharmacodynamics, and efficacy of oral 2-methoxyestradiol capsules in hormone-refractory prostate cancer. Sweeney C; Liu G; Yiannoutsos C; Kolesar J; Horvath D; Staab MJ; Fife K; Armstrong V; Treston A; Sidor C; Wilding G Clin Cancer Res; 2005 Sep; 11(18):6625-33. PubMed ID: 16166441 [TBL] [Abstract][Full Text] [Related]
3. 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta. LaVallee TM; Zhan XH; Herbstritt CJ; Kough EC; Green SJ; Pribluda VS Cancer Res; 2002 Jul; 62(13):3691-7. PubMed ID: 12097276 [TBL] [Abstract][Full Text] [Related]
4. 2-Methoxymethylestradiol: a new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics. Brueggemeier RW; Bhat AS; Lovely CJ; Coughenour HD; Joomprabutra S; Weitzel DH; Vandre DD; Yusuf F; Burak WE J Steroid Biochem Mol Biol; 2001 Aug; 78(2):145-56. PubMed ID: 11566439 [TBL] [Abstract][Full Text] [Related]
5. Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Dubey RK; Jackson EK; Keller PJ; Imthurn B; Rosselli M Hypertension; 2001 Feb; 37(2 Pt 2):640-4. PubMed ID: 11230349 [TBL] [Abstract][Full Text] [Related]
6. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Zhu BT; Conney AH Cancer Res; 1998 Jun; 58(11):2269-77. PubMed ID: 9622057 [TBL] [Abstract][Full Text] [Related]
7. A phase II study of 2-methoxyestradiol (2ME2) NanoCrystal® dispersion (NCD) in patients with taxane-refractory, metastatic castrate-resistant prostate cancer (CRPC). Harrison MR; Hahn NM; Pili R; Oh WK; Hammers H; Sweeney C; Kim K; Perlman S; Arnott J; Sidor C; Wilding G; Liu G Invest New Drugs; 2011 Dec; 29(6):1465-74. PubMed ID: 20499131 [TBL] [Abstract][Full Text] [Related]
8. Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells. Zacharia LC; Jackson EK; Gillespie DG; Dubey RK Hypertension; 2001 Feb; 37(2 Pt 2):658-62. PubMed ID: 11230352 [TBL] [Abstract][Full Text] [Related]
9. In vitro model of mammary estrogen metabolism: structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol. Dawling S; Hachey DL; Roodi N; Parl FF Chem Res Toxicol; 2004 Sep; 17(9):1258-64. PubMed ID: 15377160 [TBL] [Abstract][Full Text] [Related]
10. Pharmacogenetics of estrogen metabolism and transport in relation to cancer. Lakhani NJ; Venitz J; Figg WD; Sparreboom A Curr Drug Metab; 2003 Dec; 4(6):505-13. PubMed ID: 14683478 [TBL] [Abstract][Full Text] [Related]
11. 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6. Garcia GE; Wisniewski HG; Lucia MS; Arevalo N; Slaga TJ; Kraft SL; Strange R; Kumar AP Clin Cancer Res; 2006 Feb; 12(3 Pt 1):980-8. PubMed ID: 16467113 [TBL] [Abstract][Full Text] [Related]
13. Role of 2-methoxyestradiol, an Endogenous Estrogen Metabolite, in Health and Disease. Parada-Bustamante A; Valencia C; Reuquen P; Diaz P; Rincion-Rodriguez R; Orihuela PA Mini Rev Med Chem; 2015; 15(5):427-38. PubMed ID: 25723461 [TBL] [Abstract][Full Text] [Related]
14. The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors. Schumacher G; Neuhaus P J Cancer Res Clin Oncol; 2001 Jul; 127(7):405-10. PubMed ID: 11469676 [TBL] [Abstract][Full Text] [Related]
15. Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice. Ehteda A; Galettis P; Pillai K; Morris DL BMC Cancer; 2013 Feb; 13():86. PubMed ID: 23432760 [TBL] [Abstract][Full Text] [Related]
16. 2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer. Qadan LR; Perez-Stable CM; Anderson C; D'Ippolito G; Herron A; Howard GA; Roos BA Biochem Biophys Res Commun; 2001 Aug; 285(5):1259-66. PubMed ID: 11478793 [TBL] [Abstract][Full Text] [Related]
17. 2-Methoxyestradiol--biology and mechanism of action. Mueck AO; Seeger H Steroids; 2010 Oct; 75(10):625-31. PubMed ID: 20214913 [TBL] [Abstract][Full Text] [Related]
18. Effects of estradiol and its metabolites on glomerular endothelial nitric oxide synthesis and mesangial cell growth. Xiao S; Gillespie DG; Baylis C; Jackson EK; Dubey RK Hypertension; 2001 Feb; 37(2 Pt 2):645-50. PubMed ID: 11230350 [TBL] [Abstract][Full Text] [Related]
19. Synergism between the anticancer actions of 2-methoxyestradiol and microtubule-disrupting agents in human breast cancer. Han GZ; Liu ZJ; Shimoi K; Zhu BT Cancer Res; 2005 Jan; 65(2):387-93. PubMed ID: 15695378 [TBL] [Abstract][Full Text] [Related]
20. Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo. Sato F; Fukuhara H; Basilion JP Neoplasia; 2005 Sep; 7(9):838-46. PubMed ID: 16229806 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]