These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 12589819)

  • 1. Functional significance of the thyrotropin receptor germline polymorphism D727E.
    Sykiotis GP; Neumann S; Georgopoulos NA; Sgourou A; Papachatzopoulou A; Markou KB; Kyriazopoulou V; Paschke R; Vagenakis AG; Papavassiliou AG
    Biochem Biophys Res Commun; 2003 Feb; 301(4):1051-6. PubMed ID: 12589819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I; Lima L; Seoane R; Lado-Abeal J
    Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
    Agretti P; De Marco G; Collecchi P; Chiovato L; Vitti P; Pinchera A; Tonacchera M
    Eur J Biochem; 2003 Sep; 270(18):3839-47. PubMed ID: 12950268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization of five constitutively activating thyrotrophin receptor mutations.
    Wonerow P; Chey S; Führer D; Holzapfel HP; Paschke R
    Clin Endocrinol (Oxf); 2000 Oct; 53(4):461-8. PubMed ID: 11012571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not?
    Mueller S; Gozu HI; Bircan R; Jaeschke H; Eszlinger M; Lueblinghoff J; Krohn K; Paschke R
    Thyroid; 2009 Jul; 19(7):765-73. PubMed ID: 19583488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Constitutive activation of the thyroid-stimulating hormone receptor (TSHR) by mutating Ile691 in the cytoplasmic tail segment.
    Liu Z; Fan F; Xiao X; Sun Y
    PLoS One; 2011 Jan; 6(1):e16335. PubMed ID: 21283701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Germline polymorphism of codon 727 of human thyroid-stimulating hormone receptor is associated with toxic multinodular goiter.
    Gabriel EM; Bergert ER; Grant CS; van Heerden JA; Thompson GB; Morris JC
    J Clin Endocrinol Metab; 1999 Sep; 84(9):3328-35. PubMed ID: 10487707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Is the TSHR D727E polymorphism a genetic predisposition for multinodular goiter in the Turkish population?
    Gözü HI; Özçelik S; Aloğlu M; Şahin A; Temiz S; Dayan A; Cengiz H; Tütüncü Y; Bircan R
    Genet Mol Res; 2016 Aug; 15(3):. PubMed ID: 27525921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of the cAMP and MAPK pathways in the transformation of mouse 3T3 fibroblasts by a TSHR gene constitutively activated by point mutation.
    Du Villard JA; Wicker R; Crespo P; Russo D; Filetti S; Gutkind JS; Sarasin A; Suárez HG
    Oncogene; 2000 Oct; 19(42):4896-905. PubMed ID: 11039907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.
    Lueblinghoff J; Eszlinger M; Jaeschke H; Mueller S; Bircan R; Gozu H; Sancak S; Akalin S; Paschke R
    Thyroid; 2011 Mar; 21(3):221-9. PubMed ID: 21190443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.
    Tonacchera M; Chiovato L; Pinchera A; Agretti P; Fiore E; Cetani F; Rocchi R; Viacava P; Miccoli P; Vitti P
    J Clin Endocrinol Metab; 1998 Feb; 83(2):492-8. PubMed ID: 9467563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis.
    Esapa CT; Duprez L; Ludgate M; Mustafa MS; Kendall-Taylor P; Vassart G; Harris PE
    Thyroid; 1999 Oct; 9(10):1005-10. PubMed ID: 10560955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
    Parma J; Duprez L; Van Sande J; Cochaux P; Gervy C; Mockel J; Dumont J; Vassart G
    Nature; 1993 Oct; 365(6447):649-51. PubMed ID: 8413627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells.
    Porcellini A; Ruggiano G; Pannain S; Ciullo I; Amabile G; Fenzi G; Avvedimento EV
    Oncogene; 1997 Aug; 15(7):781-9. PubMed ID: 9266964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors.
    Cetani F; Tonacchera M; Vassart G
    FEBS Lett; 1996 Jan; 378(1):27-31. PubMed ID: 8549796
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
    Paschke R; Tonacchera M; Van Sande J; Parma J; Vassart G
    J Clin Endocrinol Metab; 1994 Dec; 79(6):1785-9. PubMed ID: 7989485
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thyrotropin receptor mutations in hyperfunctioning thyroid adenomas from Brazil.
    Nogueira CR; Kopp P; Arseven OK; Santos CL; Jameson JL; Medeiros-Neto G
    Thyroid; 1999 Nov; 9(11):1063-8. PubMed ID: 10595453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.
    Parma J; Duprez L; Van Sande J; Hermans J; Rocmans P; Van Vliet G; Costagliola S; Rodien P; Dumont JE; Vassart G
    J Clin Endocrinol Metab; 1997 Aug; 82(8):2695-701. PubMed ID: 9253356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of thyrotropin receptor residue Asp403 in a hyperfunctioning thyroid nodule provides insight into the role of the ectodomain in ligand-induced receptor activation.
    Nishihara E; Chen CR; Mizutori-Sasai Y; Ito M; Kubota S; Amino N; Miyauchi A; Rapoport B
    J Endocrinol Invest; 2012 Jan; 35(1):49-53. PubMed ID: 21597314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.