BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 12591922)

  • 1. The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells.
    Wojtanik KM; Liscum L
    J Biol Chem; 2003 Apr; 278(17):14850-6. PubMed ID: 12591922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol.
    Sugii S; Reid PC; Ohgami N; Du H; Chang TY
    J Biol Chem; 2003 Jul; 278(29):27180-9. PubMed ID: 12721287
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.
    Cruz JC; Sugii S; Yu C; Chang TY
    J Biol Chem; 2000 Feb; 275(6):4013-21. PubMed ID: 10660558
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.
    Zhang M; Dwyer NK; Neufeld EB; Love DC; Cooney A; Comly M; Patel S; Watari H; Strauss JF; Pentchev PG; Hanover JA; Blanchette-Mackie EJ
    J Biol Chem; 2001 Feb; 276(5):3417-25. PubMed ID: 11032830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
    Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
    Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1.
    Cianciola NL; Greene DJ; Morton RE; Carlin CR
    Mol Biol Cell; 2013 Nov; 24(21):3309-25. PubMed ID: 24025716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane.
    Lusa S; Blom TS; Eskelinen EL; Kuismanen E; Månsson JE; Simons K; Ikonen E
    J Cell Sci; 2001 May; 114(Pt 10):1893-900. PubMed ID: 11329376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Niemann-Pick type C mutations cause lipid traffic jam.
    Liscum L
    Traffic; 2000 Mar; 1(3):218-25. PubMed ID: 11208105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
    Frolov A; Srivastava K; Daphna-Iken D; Traub LM; Schaffer JE; Ory DS
    J Biol Chem; 2001 Dec; 276(49):46414-21. PubMed ID: 11571306
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Glick JM; Patel S; Neufeld EB; Brady RO; Pentchev PG; Strauss JF
    Proc Natl Acad Sci U S A; 1999 Feb; 96(3):805-10. PubMed ID: 9927649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking.
    Zhang M; Sun M; Dwyer NK; Comly ME; Patel SC; Sundaram R; Hanover JA; Blanchette-Mackie EJ
    Acta Paediatr Suppl; 2003 Dec; 92(443):63-73; discussion 45. PubMed ID: 14989468
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease.
    Zhang M; Dwyer NK; Love DC; Cooney A; Comly M; Neufeld E; Pentchev PG; Blanchette-Mackie EJ; Hanover JA
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4466-71. PubMed ID: 11296289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice.
    Reid PC; Sugii S; Chang TY
    J Lipid Res; 2003 May; 44(5):1010-9. PubMed ID: 12611909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Translocation of both lysosomal LDL-derived cholesterol and plasma membrane cholesterol to the endoplasmic reticulum for esterification may require common cellular factors involved in cholesterol egress from the acidic compartments (lysosomes/endosomes).
    Spillane DM; Reagan JW; Kennedy NJ; Schneider DL; Chang TY
    Biochim Biophys Acta; 1995 Feb; 1254(3):283-94. PubMed ID: 7857968
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.
    Goldman SD; Krise JP
    J Biol Chem; 2010 Feb; 285(7):4983-94. PubMed ID: 20007703
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.
    Cheruku SR; Xu Z; Dutia R; Lobel P; Storch J
    J Biol Chem; 2006 Oct; 281(42):31594-604. PubMed ID: 16606609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex.
    Urano Y; Watanabe H; Murphy SR; Shibuya Y; Geng Y; Peden AA; Chang CC; Chang TY
    Proc Natl Acad Sci U S A; 2008 Oct; 105(43):16513-8. PubMed ID: 18946045
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.
    Millard EE; Srivastava K; Traub LM; Schaffer JE; Ory DS
    J Biol Chem; 2000 Dec; 275(49):38445-51. PubMed ID: 10964915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events.
    Ko DC; Gordon MD; Jin JY; Scott MP
    Mol Biol Cell; 2001 Mar; 12(3):601-14. PubMed ID: 11251074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.
    Abi-Mosleh L; Infante RE; Radhakrishnan A; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19316-21. PubMed ID: 19884502
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.